Altered integrin expression in rheumatoid synovial lining type B cells: In vitro cytokine regulation of α1β1, α6β1, and αvβ5 integrins

Journal of Rheumatology

Volumn 23, Issue 10, 1996, Pages 1691-1698

  Pirilä, Laura ^a   Heino, Jyrki ^b  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

cytokines; integrins; synovial intima

Indexed keywords

INTEGRIN; INTERLEUKIN 1BETA; RECOMBINANT GAMMA INTERFERON; RECOMBINANT INTERLEUKIN 1BETA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CASE REPORT; CONTROLLED STUDY; FEMALE; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIUM;

ADULT; ANTIGENS, CD29; ARTHRITIS, RHEUMATOID; BLOTTING, NORTHERN; CELLS, CULTURED; CYTOKINES; FEMALE; FIBROBLASTS; HUMANS; INTEGRIN ALPHA1BETA1; INTEGRIN ALPHA6BETA1; INTEGRINS; INTERFERON TYPE II; INTERLEUKIN-1; MALE; MIDDLE AGED; MONOCYTES; PRECIPITIN TESTS; RECEPTORS, VITRONECTIN; SYNOVIAL MEMBRANE; TISSUE PLASMINOGEN ACTIVATOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0029804709     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Sack U, Kuhn H, Ermann J, et al.: Synovial tissue implants from patients with rheumatoid arthritis cause cartilage destruction in knee joints of SCID.bg mice. J Rheumatol 1994;21:10-6.
2. Zvaifler NJ, Firestein GS: Pannus and pannocytes, alternative models of joint destruction in rheumatoid arthritis. Arthritis Rheum 1995;37:783-9.
3. Edwards J, Willoughby DA: Demonstration of bone marrow derived cells in synovial lining by means of giant intracellular granules as genetic markers. Ann Rheum Dis 1982;41:177-82.
4. Shiozawa S, Shiozawa K, Fujita T: Presence of HLA-DR antigens on synovial type A and B cells: An immunoelectron microscopic study in rheumatoid arthritis, osteoarthritis, and normal traumatic joints. Immunology 1983;50:587-94.
5. Heino J, Viander M, Peltonen J, Kouri T: Adherent cells from rheumatoid synovia. Identity of HLA-DR positive stellate cells. Ann Rheum Dis 1987;46:114-20.
6. Matsubara T, Spycher MA, Rüttner JR, Fehr K: The localization of fibronectin in rheumatoid arthritis synovium by light and electron microscopic immunohistochemistry. Rheumatol Int 1983;3:153-9.
7. Okada Y, Naka K, Minamoto T, et al.: Localization of type VI collagen in the lining cell layer of normal and rheumatoid synovium. Lab Invest 1990;63:647-56.
8. Henderson B: The contribution made by cytochemistry to the study of the metabolism of the normal and rheumatoid synovial lining cell (synoviocyte). Histochem J 1982;14:527-44.
9. Dreher R: Origin of synovial type A cells during inflammation, an experimental approach. Immunobiol 1982;161:232-45.
10. Nikkari L, Aho H, Yli-Jama T, Larjava H, Jalkanen M, Heino J: Expression of integrin family of cell adhesion receptors in rheumatoid synovium. Am J Pathol 1993;142:1019-27.
11. Pollock LE, Lalor P, Revell PA: Type IV collagen and laminin in the synovial intimal layer: An immunohistochemical study. Rheumatol Int 1990;9:277-80.
12. Cutolo M, Picasso M, Ponassi M, Sun MZ, Balza E: Tenascin and fibronectin distribution in human normal and pathological synovium. J Rheumatol 1992;19:1439-47.
13. Scott DL, Delamere JP, Walton KW: The distribution of fibronectin in the pannus in rheumatoid arthritis. Br J Exp Pathol 1981;62:362-8.
14. Vartio T, Vaheri A, von Essen R, Isomäki H, Stenman S: Fibronectin in synovial fluid and tissue in rheumatoid arthritis. Eur J Clin Invest 1981;11:207-12.
15. Nikkari L, Haapasalmi K, Aho H, et al.: Localization of the alpha v subfamily of integrins and their putative ligands in synovial lining cell layer. J Rheumatol 1995;22:16-23.
16. Hynes RO, Lander AD: Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons. Cell 1992;68:303-22.
17. Ruoslahti E: Integrins. J Clin Invest 1991;87:1-5.
18. Hynes RO: Integrins: Versatility, modulation, and signalling in cell adhesion. Cell 1992;69:11-25.
19. Werb Z, Tremble PM, Behrendtsen O, Crawley E, Damsky CH: Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J Cell Biol 1989;109:877-89.
20. Larjava H, Lyons J, Salo T, et al.: Anti-integrin antibodies induce type IV collagenase expression in keratinocytes. J Cell Physiol 1993;157:190-200.
21. Tremble P, Chiquet-Ehrismann R, Werb Z: The extracellular matrix ligands fibronectin and tenascin collaborate in regulating collagenase gene expression in fibroblasts. Mol Biol Cell 1994;5:4390-3.
22. Riikonen T, Westermarck J, Koivisto L, Broberg A, Kähäri VM, Heino J: Integrin α2β1 is a positive regulator of collagenase (MMP-1) and collagen α1(1) gene expression. J Biol Chem 1995;270:13548-52.
23. Eierman DF, Johnson CE, Haskill JS: Human monocyte inflammatory mediator gene expression is selectively regulated by adherence substrates. J Immunol 1989;142:1970-6.
24. Brennan FM, Field M, Chu CQ, Feldmann M, Maini RN: Cytokine expression in rheumatoid arthritis. Br J Rheumatol 1991;30:76-80.
25. Firestein GS, Alvaro-Gracia JM, Maki R, et al. Quantitative analysis of cytokine gene expression in rheumatoid arthritis. J Immunol 1990;144:3347-53.
26. Lipsky P, Davis L, Cush J, Oppenheimer-Marks N: The role of cytokines in the pathogenesis of rheumatoid arthritis. Springer Semin Immunopathol 1989;11:123-62.
27. Siljander P, Hurme M: Continuous presence of phorbol ester is required for its IL-1β mRNA stabilizing effect. Febs Lett 1993;315:81-4.
28. Tsuchiya S, Kobayashi Y, Goto Y, et al.: Induction of maturation in cultured human monocytic leukaemia cells by a phorbol diester. Cancer Res 1982;42:1530-6.
29. Santala P, Heino J: Regulation of integrin-type cell adhesion receptors by cytokines. J Biol Chem 1991;266:23505-9.
30. Alvaro-Gracia JM, Zvaifler NJ, Firestein GS: Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between interferon-gamma and tumor necrosis factor alpha on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes. J Clin Invest 1990;86:1760-98.
31. Santala P, Larjava H, Nissinen L, Riikonen T, Maatta A, Heino J: Suppressed collagen gene expression and induction of α2β1 integrin-type collagen receptor in tumorigenic derivatives of human osteogenic sarcoma (HOS) cell line. J Biol Chem 1994;269:1276-83.
32. Heino J, Ignotz RA, Hemler ME, Crouse C, Massagué J: Regulation of cell adhesion receptors by transforming growth factor-beta. J Biol Chem 1989;264:380-8.
33. Wayner EA, Orlando RA, Cheresh DA: Integrins αvβ3 and αvβ5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. J Cell Biol 1991;113:919-29.
34. Weinacker A, Chen A, Agrez M, et al.: Role of the integrin alpha v beta 6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor. J Biol Chem 1994;269:6940-8.
35. Sonnenberg A, Hogervorst F, Osterop A, Veltman F: Identification and characterization of a novel antigen complex on mouse mammary tumour cells using a monoclonal antibody against glycoprotein Ic. J Biol Chem 1988;263:14030-8.
36. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ: Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979;18:5294-9.
37. Hogervost F, Kuikman I, van Kessel AG, Sonnenberg A: Molecular cloning of the human alpha 6 mRNA integrin subunit. Alternative splicing of alpha 6 and chromosomal localization of the alpha 6 and beta 4 genes. Eur J Biochem 1991;199:425-33.
38. Fort P, Marty L, Piechaczyk M, et al.: Various rat adult tissues express only one major mRNA species from glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res 1985;13:1431-42.
39. Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Stroker W, eds. Current Protocols in Immunology. New York: John Wiley & Sons, 1994.
40. Barland P, Novikoff AB, Hamerman D: Electron microscopy of the human synovial membrane. J Cell Biol 1962;14:207-20.
41. Bromley M, Woolley DE: Histopathology of the rheumatoid lesion. Identification of cell types at sites of cartilage erosion. Arthritis Rheum 1984;27:857-63.
42. Shiozawa S, Shiozawa K, Fujita T: Morphologic observations in the early phase of the cartilage pannus junction. Light and electron microscopic studies of active cellular pannus. Arthritis Rheum 1983;26:412-8.
43. Johnson BA, Haines GK, Harlow LA, Koch AE: Adhesion molecule expression in human synovial tissue. Arthritis Rheum 1993;36:137-46.
44. Arend WP, Dayer JM: Inhibition of the production and effects of interleukin-1 and tumour necrosis factor α in rheumatoid arthritis. Arthritis Rheum 1995;38:151-60.
45. Harris E Jr: Rheumatoid arthritis. Pathophysiology and implications for therapy. N Engl J Med 1990;322:1277-89.
46. Elliott MJ, Maini RN, Feldmann M, et al.: Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;22:1105-10.
47. Elliott M, Maini R, Feldmann M, et al.: Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis. Lancet 1994;22:1125-7.
48. Hogg N, Palmer DG, Revell PA: Mononuclear phagocytes of normal and rheumatoid synovial membrane identified by monoclonal antibodies. Immunology 1985;56:673-81.
49. Allen JB, Manthey CL, Hand AR, Ohura K, Ellingsworth L, Wahl SM: Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta. J Exp Med 1990;171:231-47.
50. Brandes ME, Allen JB, Ogawa Y, Wahl SM: Transforming growth factor β1 suppresses acute and chronic arthritis in experimental animals. J Clin Invest 1991;87:1108-13.
51. Chu CQ, Field M, Feldman M, Maini RN: Localization of tumour necrosis factor a in synovial tissues and at the cartilage/pannus junction in patients with rheumatoid arthritis. Arthritis Rheum 1991;34:1125-32.
52. Chu CQ, Field M, Abney E, et al.: Transforming growth factor β1 in rheumatoid synovial membrane and cartilage/pannus junction. Clin Exp Immunol 1991;86:380-6.
53. Chu CQ, Field M, Allard S, Feldman M, Maini RN: Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: Implications for the role of cytokines in cartilage destruction and repair. Br J Rheumatol 1992;312:653-61.
54. Firestein GS, Zvaifler NJ: Peripheral blood and synovial fluid monocyte activation in inflammatory arthritis. Arthritis Rheum 1987;30:864-71.
55. Boissier MC, Chiocchia G, Bessis N, et al.: Biphasic effect of interferon-gamma in murine collagen-induced arthritis. Eur J Immunol 1995;15:1184-90.
56. Ulfgren AK, Lindblad S, Klareskog L, Andersson J, Andersson U: Detection of cytokine producing cells in the synovial membrane from patients with rheumatoid arthritis. Ann Rheum Dis 1995;54:654-61.
57. Ishikawa H, Ohno O, Saura R, Matsubara T, Kuroda T, Hirohata K: Cytokine enhancement of monocyte/synovial cell attachment to the surface of cartilage: A possible trigger of pannus formation in arthritis. Rheumatol Int 1991;11:31-6.