Identification and characterization of metallothionein III (growth inhibitory factor) from porcine brain

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology

Volumn 115, Issue 1, 1996, Pages 27-32

  Chen, Chian Feng ^a   Wang, Sue Hong ^a   Lin, Lih Yuan ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

brain; cDNA sequence; characterization; gene expression; growth inhibitory factor; isolation; metallothionein III; porcine

Indexed keywords

METALLOTHIONEIN;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; GEL FILTRATION; GENE AMPLIFICATION; GENE EXPRESSION; ION EXCHANGE CHROMATOGRAPHY; LIVER; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ISOLATION; SWINE;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0029804668     PISSN: 03050491     EISSN: None     Source Type: Journal    
DOI: 10.1016/0305-0491(96)00080-6     Document Type: Article

References (20)

1. Ausubel, F.M.; Brent, R.; Kingston, R.E.; Moore, D.D.; Seidman, J.G.; Smith, J.A.; Struhl, K. Current Protocols in Molecular Biology. New York: John Wiley and Sons, Inc. 1989.
2. Choudhuri, S.; Kramer, K.K.; Berman, N.E.J.; Dalton, T.P. Constitutive expression of metallothionein. Toxicol. Appl. Pharmacol. 131:144-154;1995.
3. Dunn, M.A.; Blalock, T.L.; Cousins, R.J. Metallothionein. Proc. Soc. Exp. Biol. Med. 185:107-119;1987.
4. Erickson, J.C.; Sewell, A.K.; Jensen, LT.; Winge, D.R.; Palmiter, R.D. Enhance neurotrophic activity in Alzheimer's disease associated with down-regulation of metallothionein III (GIF). Brain Res. 649:297-304;1994.
5. Hamer, D.H. Metallothionen. Ann. Rev. Biochem. 55:913-951;1986.
6. Karin, M. Metallothioneins: Protein in research of functions. Cell 41:9-10;1985.
7. Kille, P.; Hemmings, A.; Lunney, E.A. Memories of metallothionein. Biochem. Biophys. Acta 1205:151-161;1994.
8. Kobayashi, H.; Uchida, Y.; Ihara, Y.; Nakajima, K.; Kohsaka, S.; Miyatake, T.; Tsuji, S. Molecular cloning of rat growth inhibitory factor cDNA and the expression in the central nervous system. Mol. Brain Res. 19:188-194;1993.
9. Masters, B.A.; Kelly, E.J.; Quaife, C.L.; Brinster, R.L; Palmiter, R.D. Targeted disruption of metallothionien I and II genes increases sensitivity to cadmium. Proc. Natl. Acad. Sci. USA 91:584-588;1994.
10. Michalsku, A.E.; Choo, K.H.A. Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse. Proc. Natl. Acad. Sci. USA 90:8088-8092; 1993.
11. Norberg, M. Ioselectric focusing of mammalian metallothioneins. Methods in Enzymol. 205:247-252;1991.
12. Palmiter, R.D.; Findley, S.D.; Whitmore, T.E.; Durman, D.M. MT-III, a brain-specific member of the metallothionein gene family. Proc. Natl. Acad. Sci. USA 89:6333-6337;1992.
13. Pountney, D.L.; Fundel, S.M.; Faller, P.; Brichler, N.E.; Hunziker, P.; Vasak, M. Isolation, primary structure and metal binding properties of neuron growth inhibitory factor (GIF) from bovine and equine brain. FEBS Lett. 345:193-197;1994.
14. Quaife, C.J.; Findley, S.D.; Erickson, J.C.; Froelick, G.J.; Kelley, E.J.; Zambrowicz, B.P.; Palmiter, R.D. Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia. Biochemistry 33:7250-7259;1994.
15. Sanger, F.; Nicklen, S.; Coulson, A.R. DNA sequencing with chain termination inhibitors. Proc. Natl. Acad. Sci. USA 74: 5463-5467;1977.
16. Tsuji, S.; Kobayashi, H.; Uchida, Y.; Miyatake, T. Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzhemer's disease. EMBO J. 11:4843-4850;1992.
17. Uchida, Y.; Ihara, Y. The N-terminal protein of growth inhibitory factor is sufficient fur biological activity. J. Biol. Chem. 270:3365-3369;1995.
18. Uchida, Y.; Takio, K.; Titani, K.; Ihara, Y.; Tomonaga, M. The growth inhibitory factor that is deficient in the Alzheimer's disease brain is 68 amino acid metallothionein-like protein. Neuron 7:337-347;1991.
19. Vasak, M. Standard isolation procedure for metallothionein. Methods in Enzymol. 205:41-44;1991.
20. Yuguchi, T.; Kohmura, E.; Yamada, K.; Sakaki, T.; Yamashida, T.; Otsuki, H.; Wanaka, A.; Tohyama, M.; Tsuji, S.; Hayakawa, T. Changes in growth inhibitory factor mRNA expression following facial nerve transections. Mol. Brain Res. 28: 181-185;1995.