Influence of the antineoplastic agent cyclophosphamide on dental development in rat molars

Acta Odontologica Scandinavica

Volumn 54, Issue 5, 1996, Pages 287-294

  Näsman, Margareta ^a   Hammarström, Lars ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

dental pulp; dentin; developmental disturbances; osteodentin

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DENTIN; DRUG EFFECT; ENAMEL; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; RAT; TOOTH DEVELOPMENT; TOOTH DISEASE; TOOTH PULP;

EID: 0029804345     PISSN: 00016357     EISSN: None     Source Type: Journal    
DOI: 10.3109/00016359609003540     Document Type: Article

References (25)

1. Gustafsson G, Garwicz S, Hertz H. A population-based study of childhood acute lymphoblastic leukemia diagnosed from July 1981 through June 1985 in the five Nordic countries. Acta Paediatr Scand 1987;76:781-7.
2. Byrd R. Late effects of treatment of cancer in children. Pediatr Clin North Am 1985;32:840-56.
3. Jaffe N, Toth BB, Haer RE, Ried HL, Sullivan MP, McNeese MD. Dental and maxillofacial abnormalities in long-term survivors of childhood cancer. Effects of treatment with chemotherapy and radiation of the head and neck. Pediatrics 1984;73:816-23.
4. Maguire A, Murray JJ, Craft AW, Kernahan J, Wclbury R. Radiological features of the long-term effects from treatment of malignant disease in childhood. Br Dent J 1987;162:99-102.
5. Koppang HS. Dental damage after radiotherapy for malignant lesions in the head and neck region. Nor Tannlaegeforen Tid 1975;85:159-65.
6. Dahllöf G, Barr M, Bolme P. Disturbances in dental development after total body irradiation in bone marrow transplant recipients. Oral Surg Oral Med Oral Pathol 1988;65:41-41.
7. Rosenberg SW, Kolodney II, Wong GY. Altered dental root development in long-term survivors of pediatric acute lymphoblastic leukemia. A review of 17 cases. Cancer 1987;59:1640-8.
8. Nàsman M, Bjork O, Soderhall S, Ringdén O, Dahllöf G. Disturbances in the oral cavity in pediatric long-term survivors after different forms of antineoplastic therapy. Pediatr Dent 1994;16:217-23.
9. Calabresi P, Parks RE, Alkylating agents, antimetabolites, hormones and other antiproliferative agents. In: Goodman LS, Gilman A, editors. The pharmacologic basis of therapeutics, 4th ed. New York: Macmillan 1962:1348-95.
10. Nordlinder H. Malformations in newborn rats treated with a single dose of cyclophosphamide. Acta Soc Med Upsal 1971; 76:90-7.
11. Koppang HS. Histomorphologic investigations on the effect of cyclophosphamide on dentinogenesis of the rat incisors. Scand J Dent Res 1973;81:383-96.
12. Adatia AK. The effects of cyclophosphamide on odonogenesis in the rat. Arch Oral Biol 1975;20:141-4.
13. Vahlsing HL, Sun-Kee K, Feringa ER. Cyclophosphamide-induced abnormalities in the incisors of the rat. J Dent Res 1977;56:809-16.
14. Adaria AK. Cytotoxity of cyclophosphamide in the rat incisor. Br J Cancer 1975;32:208-18.
15. Vahlsing HL, Ferringa ER, Britten AG, Kinning WK. Dental abnormalities in rats after a singre large dose of cyclophosphamide. Cancer 1975;35:2199-202.
16. Koppang HS. Histomorphologic investigations of dentinogenesis in incisors of off-spring of cyclophosphamide-treated pregnant rats. Scand J Dent Res 1978;86:444-58.
17. Adaua AK, Berkovitz BKB. The effects of cyclophosphamide on eruption of the continuously growing mandibular incisor of the rat. Arch Oral Biol 1981;26:607-13.
18. Karim AC, Pylypas SP. Osteodentin formation in rat incisors as visualized by radioautography after 3H-proline administration. Anat Rec 1986;216:19-26.
19. Karim AC, Eddy EL. A light and electron microscopic study of osteodentin formation in the rat incisor after adriamycin administration. Am J Anat 1984;169:207-19.
20. Karim AC, Woltgens JHM, Bervoets TH, Lyaruu DM, Bronckers AL Effect of adriamycin on hamster molar tooth development in vitro. I. Morphological changes. Anat Rec 1989; 225:318-28.
21. Mikkelsen HB. Acute and protracted effects of vinblastine on odontoblasts and dentinogenesis in rat incisors. Scand J Dent Res 1978;86:313-24.
22. Stene T. Vincristine's effect on dentinogenesis in rat incisor. J Dent Res 1979;87:34-9.
23. Noguiera TD, Stene T, Koppang HS. Colchicine's effect on rat incisor odontoblasts and dentinogenesis. Scand J Dent Res 1981; 89:48-58.
24. Kurahashi Y, Nagai N, Wertanabe K, Watanabe H, Yama K. Chronological observation of the odontogenesis of rat molars. Bull Tokyo Med Dent Coll 1968;4:147-59.
25. Koppang H. Effect of cyclophosphamide on dentinogenesis in the rat incisor: fluorescence microscopic and microradiographic investigations. Scand J Dent Res 1981;89:59-70.