Efficient two-step synthesis of sulfonylguanidines from sulfonamides

Synthetic Communications

Volumn 26, Issue 23, 1996, Pages 4299-4310

  Deprez, Pierre ^a   Vevert, Jean Paul ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GUANIDINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; INFRARED SPECTROPHOTOMETRY; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS;

EID: 0029803979     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919608003832     Document Type: Article

References (30)

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30. 1. If they proved to be 5 to 10-fold less potent than the corresponding sulfonylurea HR 720, their in vitro potency was in similar range (2-5 nmol) to that of DuP 753, the only AII antagonist on the market at the moment.