Clearance of antitransferrin receptor immunotoxin from the rabbit eye

Current Eye Research

Volumn 15, Issue 10, 1996, Pages 1039-1044

  Handa, James T ^a   Pearson, P Andrew ^b,c   Jaffe, Glenn J ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DUKE UNIVERSITY EYE CENTER   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Antitransferrin receptor immunotoxin; Pharmacokinetics; Proliferative vitreoretinopathy; Rabbit

Indexed keywords

IMMUNOTOXIN; TRANSFERRIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CORNEA DISEASE; CORNEA EPITHELIUM; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG TISSUE LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RABBIT; SCAR FORMATION; TRABECULECTOMY; VITRECTOMY; VITREORETINOPATHY; VITREOUS BODY;

EID: 0029803604     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.3109/02713689609017653     Document Type: Article

References (16)

1. Bjorn, M. J., Ring, D. and Frankel, A. (1985) Evaluation of monoclonal antibodies for the development of breast cancer immunotoxins. Cancer Res. 45, 1214-1221.
2. Jaffe, G. J., Earnest, K., Fulcher, S. F., Lui, G. M. and Houston, L. L. (1990) Antitransferrin receptor immunotoxin inhibits proliferating human retinal pigment epithelial cells. Arch. Ophthalmol. 108, 1163-1168.
3. Fulcher, S., Lui, G., Houston, L. L., Ramakrishnan, S., Burris, T., Polansky, J. and Alvarad, J. (1988) Use of immunotoxin to inhibit proliferating human corneal endothelium. Invest. Ophthalmol. Vis. Sci. 29, 755-759.
4. Ortiz, J. R., Goins, K., Fulcher, S. F. A., Handa, J. T., Jaffe, G. J., Wilkerson, M., Hatchell, D. L., Cobo, M. and Foulks, G. N. (1991) The effect of immunotoxin 454A12-rRA on proliferating human and rhesus monkey corneal epithelium. (Abstract). Invest. Ophthalmol. Vis. Sci. 32 (Suppl.), 843.
5. Lincoff, H., Horowitz, J., Kreissig, I. and Jacobiec, F. (1986) Morphological effects of gas compression on the cortical vitreous. Arch. Ophthalmol. 104, 1212-1215.
6. Lincoff, H., Kreissig, I., Fuchs, W., Jakobiec, F. and Iwamoto, T. (1984) Total displacement of the vitreous by an expanding gas in a rabbit model. Fortsch. Ophthalmol. 81, 95-98.
7. Abel, R., Jr, and Boyle, G. L. (1976) Dissecting ocular tissue for intraocular drug studies. Invest. Ophthalmol. Vis. Sci. 13, 216-219.
8. Frankel, A. E., Ring, D. B., Tringale, F. and Hsieh-Ma, S. T. (1985) Tissue distribution of breast cancer associated antigens defined by monoclonal antibodies. J. Biol. Response Mod. 4, 273-286.
9. Enzyme-Linked Immunosorbent Assays (ELISA). (1991) In Current Protocols in Molecular Biology (Eds. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A. and Struhl, K.). Pp. 11.2.1-11.2.22. John Wiley & Sons, Inc., New York.
10. Maurice, D. M. (1976) Injection of drugs into the vitreous body. In Symposium on Ocular Therapy (Eds. Leopold, J. and Burns, R.). Pp. 59-71. John Wiley & Sons, Inc., New York.
11. Lim, J. I., Maguire, A. M., John, G., Mohler, M. A. and Fiscella, R. G. (1993) Intraocular tissue plasminogen activator concentrations after subconjunctival delivery. Ophthalmology, 100, 373-376.
12. Amlot, P. L., Stone, M. J., Cunningham, D., Fay, J., Newman, J., Collins, R., May, R., McCarthy, M., Richardson, J. and Ghetic, V. (1993) A phase I study of an anti-CD22-deglycosylated ricin A chain immunotoxin in the treatment of B-cell lymphomas resistant to conventional therapy. Blood, 82, 2624-2633.
13. Grossbard, M. L., Freedman, A. S., Ritz, J., Coral, F., Goldmacher, V. S., Eliseo, L., Spector, N., Dean, K., Lambert, J. M. and Blattler, W. A. (1990) Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: a phase I trial of daily bolus infusion. Blood, 79, 576-585.
14. Handa, J. T., Houston, L. L. and Jaffe, G. J. (1993) Monensin enhances the cytotoxic effect of antitransferrin receptor immunotoxin on cultured RPE cells. Curr. Eye Res. 12, 45-53.
15. Baudouin, C., Brignol, F., Fredj-Reygrobellet, D., Negre, F., Bayle, J. and Gastaud, P. (1992) Transferrin receptor expression by retinal pigment epithelial cells in proliferative vitreoretinopathy. Invest. Ophthalmol. Vis. Sci. 33, 2822-2829.
16. Handa, J. T., Keithahn, M. A. and Jaffe, G. J. (1994) Transferrin-ricin A chain toxin prevents the development of experimental proliferative vitreoretinopathy. (Abstract). Invest. Ophthalmol. Vis. Sci. 36 (Suppl.), S748.