Regulation of sucrase-isomaltase and hexose transporters in Caco-2 cells: A role for cytochrome P-4501A1?

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 270, Issue 6 33-6, 1996, Pages

  Carrière, Véronique ^a   Barbat, Alain ^b   Rousset, Monique ^b   Brot Laroche, Edith ^b   Dussaulx, Elisabeth ^b   Cambier, Danièle ^b   De Waziers, Isabelle ^b   Beaune, Philippe ^b   Zweibaum, Alain ^b  

^a INSERM   (France)

^b NONE

Author keywords

Caco 2 clones; glucose consumption; GLUT 1; GLUT 2; GLUT 3; GLUT 5; SGLT 1

Indexed keywords

CYTOCHROME P450; SUCRASE ISOMALTASE;

ANIMAL CELL; ARTICLE; CELL GROWTH; GENE EXPRESSION REGULATION; GLUCOSE INTAKE; GLUCOSE UTILIZATION; HEXOSE TRANSPORT; INTESTINE ABSORPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

EID: 0029803284     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1996.270.6.g976     Document Type: Article

References (36)

1. +-dependent sugar transport in Caco-2 cells and human fetal colon. J. Membr. Biol. 99: 113-125, 1987.
2. Boulenc, X., M. Bourrie, I. Fabre, C. Roque, H. Joyeux, Y. Berger, and G. Fabre. Regulation of cytochrome P-450IA1 gene expression in a human intestinal cell line, Caco-2. J. Pharmacol. Exp. Ther. 263: 1471-1478, 1992.
3. Caro, I., X. Boulenc, M. Rousset, V. Meunier, M. Bourrié, B. Julian, H. Joyeux, C. Roques, Y. Berger, A. Zweibaum, and G. Fabre. Characterization of a newly isolated Caco-2 clone (TC-7), as a model of transport processes and biotransformation of drugs. Int. J. Pharm. 116: 147-158, 1995.
4. Chantret, I., M. Lacasa, G. Chevalier, J. Ruf, I. Islam, N. Mantei, Y. Edwards, D. Swallow, and M. Rousset. Sequence of the complete cDNA and the 5′ structure of the human sucrase-isomaltase gene. Possible homology with a yeast glucoamylase. Biochem. J. 285: 915-923, 1992.
5. Chantret, I., M. Lacasa, G. Chevalier, D. Swallow, and M. Rousset. Monensin and forskolin inhibit the transcription rate of sucrase-isomaltase but not the stability of its mRNA in Caco-2 cells. FEBS Lett. 328: 55-58, 1993.
6. Chantret, I., A. Rodolosse, A. Barbat, E. Dussaulx, E. Brot-Laroche, A. Zweibaum, and M. Rousset. Differential expression of sucrase-isomaltase in clones isolated from early and late passages of the cell line Caco-2: evidence for a glucose-dependent negative regulation. J. Cell Sci. 107: 213-225, 1994.
7. Charrasse, S., I. Fabre, M. Daujat, P. Maurel, and C. Larroque. Cytochrome P4501A1 expression during the differentiation process in the Caco-2 cell line. In: Cytochrome P450, edited by M. C. Lechner. Montrouge, France: John Libbey Eurotext, 1994, 8th International Conference, p. 825-829.
8. Chirgwin, J. M., A. E. Przybyla, R. J. MacDonald, and W. J. Rutter. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18: 5294-5299, 1979.
9. Curi-Pedrosa, R., M. Daujat, L. Pichard, J. C. Ourlin, P. Clair, L. Gervot, P. Lesca, J. Domergue, H. Joyeux, G. Fourtanier, and P. Maurel. Omeprazole and lansoprazole are mixed inducers of CYP1A and CYP3A in human hepatocytes in primary culture. J. Pharmacol. Exp. Ther. 269: 384-392, 1994.
10. Darmoul, D., M. Lacasa, I. Chantret, D. Swallow, and G. Trugnan. Isolation of cDNA probe for the human intestinal dipetidylpeptidase IV and assignment of the gene locus DPPIV to chromosome 2. Ann. Hum. Genet. 54: 191-197, 1990.
11. Diaz, D., I. Fabre, M. Daujat, B. Saint Aubert, P. Bories, H. Michel, and P. Maurel. Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450. Gastroenterology 99: 737-747, 1990.
12. Fernandez-Salguero, P., T. Pineau, D. M. Hilbert, T. McPhail, S. S. T. Lee, S. Kimura, D. W. Nebert, S. Rudikoff, J. M. Ward, and F. J. Gonzalez. Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science Wash. DC 268: 722-726, 1995.
13. Gautier, J. C., P. Urban, P. Beaune, and D. Pompon. Engineered yeast cells as a model to study coupling between human xenobiotic metabolizing enzyme. Simulation of the two first steps of berizo [a] pyrene activation. Eur. J. Biochem. 211: 63-72, 1993.
14. Gonzalez, F. J., S. Y. Liu, and M. Yano. Regulation of cytochrome P450 genes: molecular mechanisms. Pharmacogenetics 3: 51-57, 1993.
15. Green, F., Y. Edwards, H. P. Hauri, S. Povey, M. W. Ho, M. Pinto, and D. Swallow. Isolation of a cDNA probe for a human jejunal brush border hydrolase, sucrase-isomaltase, and assignment of the gene locus to chromosome 3. Gene 57: 101-110, 1987.
16. Harris, D. S., J. W. Slot, H. J. Geuze, and D. E. James. Polarized distribution of glucose transporter isoforms in Caco-2 cells. Proc. Natl. Acad. Sci. USA 89: 7556-7560, 1992.
17. Hauri, H. P., E. E. Sterchi, D. Bienz, M. A. Fransen, and A. Marxer. Expression of intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells. J. Cell Biol. 101, 838-851, 1985.
18. Hediger, M., M. J. Coady, T. S. Ikeda, and E. M. Wright. Expression cloning and cDNA sequencing of the Na/glucose co-transporter. Nature Lond. 330: 379-381, 1987.
19. Lesuffleur, T., A. Barbat, E. Dussaulx, and A. Zweibaum. Growth adaptation to methotrexate of HT-29 human colon carcinoma cells is associated with their ability to differentiate into columnar absorptive and mucus-secreting cells. Cancer Res. 50: 6334-6343, 1990.
20. Mahraoui, L., A. Rodolosse, A. Barbat, E. Dussaulx, A. Zweibaum, M. Rousset, and E. Brot-Laroche. Presence and differential expression of SGLT1, GLUT1, GLUT2, GLUT3, and GLUT5 hexose-transporter mRNAs in Caco-2 cell clones in relation to cell growth and glucose consumption. Biochem. J. 298: 629-633, 1994.
21. Mahraoui, L., M. Rousset, E. Dussaulx, D. Darmoul, A. Zweibaum, and E. Brot-Laroche. Expression and localization of GLUT-5 in Caco-2 cells, human small intestine and colon. Am. J. Physiol. 263 (Gastrointest. Liver Physiol. 26): G312-G318, 1992.
22. McDonnell, W. M., J. M. Scheiman, and P. G. Traber. Induction of cytochrome P450IA genes (CYP1A) by omeprazole in the human alimentary tract. Gastroenterology 103: 1509-1516, 1992.
23. Nebert, D. W. Proposed role of drug-metabolizing enzymes: regulation of steady state levels of the ligands that effect growth, homeostasis, differentiation, and neuroendocrine functions. Mol. Endocrinol. 5: 1203-1214, 1991.
24. Nelson, D. R., T. Kamataki, D. J. Waxman, F. P. Guengerich, R. W. Estabrook, R. Feyereisen, F. J. Gonzalez, M. J. Coon, I. C. Gunsalus, O. Gotoh, K. Okuda, and D. W. Nebert. The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA Cell Biol. 12: 1-51, 1993.
25. Noll, F. Determination of lactate with LDH, GPT and NAD. In: Methods of Enzymatic Analysis. New York: Academic, 1974, p. 1475-1477.
26. Okey, A. B. Enzyme induction in the cytochrome P-450 system. Pharmacol. Ther. 45: 241-298, 1990.
27. Pinto, M., S. Robine-Léon, M. D. Appay, M. Kedinger, N. Triadou, E. Dussaulx, B. Lacroix, P. Simon-Assmann, K. Haffen, J. Fogh, and A. Zweibaum. Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture. Biol. Cell. 47: 323-330, 1983.
28. Pringault, E., M. Arpin, A. Garcia, J. Finidori, and D. Louvard. A human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo and in culture. EMBO J. 5: 3119-3124, 1986.
29. Robine, S., C. Huet, R. Moll, C. Sahuquillo-Merino, E. Coudrier, A. Zweibaum, and D. Louvard. Can villin be used to identify malignant and undifferentiated normal digestive epithelial cells? Proc. Natl. Acad. Sci. USA 82: 8488-8492, 1985.
30. Rosenberg, D. W., and T. Leff. Regulation of cytochrome P450 in cultured human colonic cells. Arch. Biochem. Biophys. 300. 186-192, 1993.
31. Rousset, M., I. Chantret, D. Darmoul, G. Trugnan, C. Sapin, F. Green, D. Swallow, and A. Zweibaum. Reversible forskolin-induced impairment of sucrase-isomaltase mRNA levels, biosynthesis and transport to the brush border membrane in Caco-2 cells. J. Cell. Physiol. 141: 627-635, 1989.
32. Sadek, C. M., and B. L. Allen-Hoffmann. Cytochrome P-450IA1 is rapidly induced in normal human keratinocytes in the absence of xenobiotics. J. Biol. Chem. 269: 16067-16074, 1994.
33. Thomas, P. S. Hybridization of denatured mRNA and small DNA fragments transferred to nitrocellulose. Proc. Natl. Acad. Sci. USA 77: 5201-5205, 1980.
34. Traber, P. G., W. Wang, and L. Yu. Differential regulation of cytochrome P-450 genes along rat intestinal crypt-villus axis. Am. J. Physiol. 263 (Gastrointest. Liver Physiol. 26): G215-G223, 1992.
35. Yamamoto, T., Y. Seino, H. Fukumoto, G. Koh, G. Yano, N. Inagaki, Y. Yamada, K. Inoue, T. Manabe, and H. Imura. Over-expression of facilitative glucose transporter genes in human cancer. Biochem. Biophys. Res. Commun. 170: 223-230, 1990.
36. Zweibaum, A., M. Laburthe, E. Grasset, and D. Louvard. Use of cultured cell lines in studies of intestinal cell differentiation and function. In: Handbook of Physiology. The Gastrointestinal System. Intestinal Absorption and Secretion. Bethesda, MD: Am. Physiol. Soc., 1991, sect. 6, vol. IV, chapt. 7, p. 223-255.