Radiation-induced apoptosis in thymocytes: Inhibition by diethyldithiocarbamate and zinc

Radiation Research

Volumn 146, Issue 6, 1996, Pages 652-659

  Mathieu, Jacques ^a   Ferlat, Sylvie ^a   Ballester, Bruno ^a   Platel, Sandrine ^a   Herodin, Francis ^a   Chancerelle, Yves ^a   Mestries, Jean Claude ^a   Kergonou, Jean François ^a  

^a CENTRE DE RECHERCHES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DIETHYLDITHIOCARBAMIC ACID; MEROCYANINE; RHODAMINE 123; ZINC;

ADOLESCENT; ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ETIOLOGY; FEMALE; GAMMA IRRADIATION; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PREVENTION; PRIORITY JOURNAL; RADIATION INJURY; THYMOCYTE;

ANIMALIA;

EID: 0029803272     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579381     Document Type: Article

References (54)

1. J. F. R. Kerr, A. H. Wyllie and A. R. Currie, Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257 (1972).
2. G. B. Bulkley, The role of oxygen free radicals in human disease processes. Surgery 94, 407-411 (1983).
3. T. M. Buttke and P. A. Sandstrom, Oxidative stress as a mediator of apoptosis. Immunol. Today 15, 7-10 (1994).
4. J. D. Ashwell, R. H. Schwartz, J. B. Mitchell and A. Russ, Effect of γ radiation on resting B lymphocytes. J. Immunol. 136, 3649-3656 (1986).
5. N. Ramakrishnan, D. E. McClain and G. N. Catravas, Membranes as sensitive targets in thymocyte apoptosis. Int. J. Radiat. Biol. 63, 693-701 (1993).
6. V. F. Forrest, Y. H. Kang, D. E. McClain, D. H. Robinson and N. Ramakrishnan, Oxidative stress-induced apoptosis prevented by trolox. Free Radicals Biol. Med. 16, 675-684 (1994).
7. R. A. Schlegel, M. Stevens, K. Lumley-Sapansli and P. Williamson, Altered lipid packing identifies apoptotic thymocytes. Immunol. Lett. 36, 283-288 (1993).
8. L. McEvoy, P. Williamson and R. A. Schlegel, Membrane phospholipid asymmetry as a determinant of erythrocyte recognition by macrophages. Proc. Natl. Acad. Sci. USA 83, 3311-3314 (1986).
9. P. Williamson, K. Mattocks and R. A. Schlegel, MC540, a fluorescent probe sensitive to lipid packing. Biochim. Biophys. Acta 732, 387-391 (1983).
10. S. Vukmanovic and R. Zamoyska, Anti-CD3-induced cell death in T cell hybridomas: mitochondrial failure and DNA fragmentation are distinct events. Eur. J. Immunol. 21, 419-424 (1991).
11. J. P. Zoeteweij, B. Van de Water, H. J. G. M. De Bont, G. J. Mulder and J. F. Nagelkerke, Calcium-induced cytotoxicity in hepatocytes after exposure to extracellular ATP is dependent on inorganic phosphate. Effects on mitochondrial calcium. J. Biol. Chem. 268, 3384-3388 (1993).
12. J. L. Vayssiere, P. X. Petit, Y. Risler and B. Mignotte, Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc. Natl. Acad. Sci. USA 91, 11752-11756 (1994).
13. L. V. Johnson, M. L. Walsh and L. B. Chen, Localization of mitochondria in living cells with rhodamine 123. Proc. Natl. Acad. Sci. USA 77, 990-994 (1980).
14. N. Ramakrishnan and G. N. Catravas, N-(2-Mercaptoethyl)-1,3-propanediamine (WR-1065) protects thymocytes from programmed cell death. J. Immunol. 148, 1817-1821 (1992).
15. G. Renoux, Immunopharmacologie et pharmacologie du diéthyldithiocarbamate (DTC). J. Pharmacol. 13, 95-134 (1982).
16. S. H. Kim, C. K. Cho, S. Y. Yoo, K. H. Koh, H. G. Yun and T. H. Kim, In vivo radioprotective activity of Panax ginseng and diethyldithiocarbamate. In Vivo 7, 467-470 (1993).
17. H. P. Misra, Reaction of copper-zinc superoxide dismutase with diethyldithiocarbamate, J. Biol. Chem. 254, 11623-11628 (1979).
18. E. M. Walker, M. A. Fazekas-May, K. W. Heard, S. Yee, D. Montague and M. M. Jones, Prevention of cisplatin-induced toxicity by selected dithiocarbamates. Ann. Clin. Lab. Sci. 24, 121-133 (1994).
19. A. Mulsch, B. Schray-Utz, P. I. Mordvintcev, S. Hauschildt and R. Busse, Diethyldithiocarbamate inhibits induction of macrophage NO synthase. FEBS Lett. 321, 215-218 (1993).
20. C. W. Broner, J. L. Shenep, D. C. Stokes, D. Fairclough, W. K. Hildner, S. A. Storgion and J. E. Regh, Reversal of dopamine-refractory septic shock by diethyldithiocarbamate, an inhibitor of endotheliumderived relaxing factor. J. Infect. Dis. 167, 141-147 (1993).
21. M. I. Walton, D. Whysong, P. M. O'Connor, D. Hockenbery, S. J. Korsmeyer and K. W. Kohn, Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis. Cancer Res. 53, 1853-1861 (1993).
22. W. J. Bettger. Zinc and selenium, site-specific versus general antioxidation. Can. J. Physiol. Pharmacol. 71, 721-724 (1993).
23. M. G. Ormerod, M. K. I. Collins, G. Rodriguez-Tarduchy and D. Robertson, Apoptosis in interleukin-3-dependent haemopoietic cells. J. Immunol. Methods 153, 57-65 (1992).
24. I. Nicoletti, G. Migliorati, M. C. Pagliacci, F. Grignani and C. A. Riccardi, A rapid and simple method for measuring thymocyte apoptosis by PI staining and flow cytometry. J. Immunol. Methods 139, 271-279 (1992).
25. W. Gorczyca, J. Gong and Z. Darzynkiewicz, Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res. 53, 1945-1951 (1993).
26. K. S. Sellins and J. J. Cohen, Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes. J. Immunol. 139, 3199-3206 (1987).
27. J. J. Cohen and R. C. Duke, Glucocorticoid activation of a calciumdependent endonuclease in thymocyte nuclei leads to cell death. J. Immunol. 132, 38-42 (1984).
28. K. Burton, A study of the conditions and mechanism of the DPA reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem. J. 62, 315-323 (1956).
29. W. G. Telford, L. E. King and P. J. Fraker, Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry. Cytometry 13, 137-143 (1992).
30. F. Ojeda, M. I. Guarda, C. Maldonado and H. Folch, A flow-cytometric method to study DNA fragmentation in lymphocytes. J. Immunol. Methods 152, 171-176 (1992).
31. M. A. Hotz, F. Traganos and Z. Darzynkiewicz, Changes in nuclear chromatin related to apoptosis or necrosis induced by the DNA topoisomerase II inhibitor fostriecin in MOLT-4 and HL-60 cells are revealed by altered DNA sensitivity to denaturation. Exp. Cell Res. 201, 184-191 (1992).
32. Z. Darzynkiewicz, S. Bruno, G. Del Bino, W. Gorczyca, M. A. Hotz, P. Lassota and F. Traganos, Features of apoptotic cells measured by flow cytometry. Cytometry 13, 795-808 (1992).
33. N. V. Afanasyev, B. A. Korol, N. P. Matylevitch, V. A. Pechatnikov and S. R. Umansky, The use of flow cytometry for the investigation of cell death. Cytometry 14, 603-609 (1993).
34. T. W. McCloskey, N. Oyaizu, M. Coronesi and S. Pahwa, Use of a flow cytometric assay to quantitate apoptosis in human lymphocytes. Clin. Immunol. Immunopathol. 71, 14-18 (1994).
35. D. A. Mower, D. W. Peckham, V. A. Illera, J. K. Fishbaugh, L. L. Stunz and R. F. Ashman, Decreased membrane phospholipid packing and decreased cell size precede DNA cleavage in mature mouse B cell apoptosis. J. Immunol. 152, 4832-4842 (1994).
36. F. Oberhammer, G. Fritsch, M. Schmied, M. Pavelka, D. Printz, T. Purchio, H. Lassmann and R. Schulte-Hermann, Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease. J. Cell Sci. 104, 317-326 (1993).
37. D. Y. Sun, S. Jiang, L. M. Zheng, D. M. Ojcius and J. D. E. Young, Separate metabolic pathways leading to DNA fragmentation and apoptotic chromatin condensation. J. Exp. Med. 179, 559-568 (1994).
38. D. M. Hockenbery, G. Nunez, C. Milliman, R. D. Schreiber and S. J. Korsmeyer, Bcl-2 is an inner mitochondrial membrane protein that blocks PCD. Nature 348, 334-336 (1990).
39. M. D. Jacobson, J. F. Burne, M. P. King, T. Miyashita, J. C. Reed and M. C. Raff, Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA. Nature 348, 334-336 (1990).
40. P. Skowronek, O. Haferkamp and G. Rodel, A fluorescence microscopic and flow-cytometric study of HeLa cells with an experimentally induced respiratory deficiency. Biochem. Biophys. Res. Commun. 187, 991-998 (1992).
41. D. M. Hockenbery, Z. N. Oltvai, X. M. Yin, C. L. Milliman and S. J. Korsmeyer, Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75, 241-251 (1993).
42. D. J. Kane, T. A. Sarafian, R. Anton, H. Hahn, E. B. Gralla, J. S. Valentine, T. Ord and D. E. Bredesen, Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science 262, 1274-1277 (1993).
43. 2+, homeostasis, cell death, proliferation and differentiation. Chem. Biol. Interact. 77, 1-23 (1991).
44. T. E. Gunter, K. K. Gunter, S. S. Sheu and C. E. Gavin, Mitochondrial calcium transport: physiological and pathological relevance. Am. J. Physiol. 267, C313-C339 (1994).
45. G. Baffy, T. Miyashita, J. R. Williamson and J. C. Reed, Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced bcl-2 oncoprotein production. J. Biol. Chem. 268, 6511-6519 (1993).
46. T. Buttke and P. Sandstrom, Redox regulation of programmed cell death in lymphocytes. Free Radical Res. 22, 389-397 (1995).
47. 2+-mediated endonuclease activation. Science 242, 256-258 (1988).
48. 2+-dependent endonuclease in apoptosis. Biochem. Biophys. Res. Commun. 190, 1097-1103 (1993).
49. P. Brennan and L. O'Neil, Effects of oxidants and antioxidants on nuclear factor KB activation in three different cell lines. Biochim. Biophys. Acta 1260, 167-175 (1995).
50. D. J. Chang, G. M. Ringold and R. A. Heller, Cell killing and induction of manganese Superoxide dismutase by TNFα is mediated by lipoxygenase metabolites of arachidonic acid. Biochem. Biophys. Res. Commun. 188, 538-546 (1992).
51. A. Cossariza, G. Kalshinikova, E. Grassilli, F. Chiapelli, S. Salvioli, M. Capri, D. Barbieri, L. Troiano, D. Monti and C. Franceschi, Mitochondrial modifications during rat thymocyte apoptosis: a study at the single cell level. Exp. Cell Res. 214, 4832-4842 (1994).
52. A. Cossariza, C. Franceschi and D. Monti, Protective effect of N-actylcysteine in tumor necrosis factor-alpha-induced apoptosis in U937 cells: the role of mitochondria. Exp. Cell Res. 220, 232-240 (1995).
53. M. Mayer and M. Noble, N-Actyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro. Proc. Natl. Acad. Sci. USA 91, 7696-7500 (1994).
54. K. S. Sellins and J. J, Cohen, Hyperthermia induces apoptosis in thymocytes. Radiat Res. 126, 88-95 (1991).