Protein C activation on endothelial cells by prothrombin activation products generated in situ: Meizothrombin is a better protein C activator than α-thrombin

Biochemical Journal

Volumn 319, Issue 2, 1996, Pages 399-405

  Hackeng, Tilman M ^a,c   Tans, Guido ^b   Koppelman, Stefan J ^a   De Groot, Philip G ^a   Rosing, Jan ^b   Bouma, Bonno N ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A; INTERLEUKIN 1; MEIZOTHROMBIN; PROTEIN C; PROTEIN S; PROTHROMBIN; THROMBIN; THROMBOMODULIN; TUMOR NECROSIS FACTOR;

ARTICLE; BLOOD CLOTTING; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; NEGATIVE FEEDBACK; PRIORITY JOURNAL;

EID: 0029803229     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3190399     Document Type: Article

References (54)

1. Esmon, C. T. (1993) Thromb. Haemost. 70, 29-35
2. Kisiel, W., Canfield, W. M., Ericsson, L. H. and Davie, E. W. (1977) Biochemistry 16, 5824-5331
3. Kisiel, W. (1979) J. Clin. Invest. 64, 761-769
4. Walker, F. J., Sexton, P. W. and Esmon, C. T. (1979) Biochim. Biophys. Acta 571, 333-342
5. Venar, G. A. and Davie, E. W. (1980) Biochemistry 19, 401-410
6. Marlar, R. A., Kleiss, A. J. and Griffin, J. H. (1982) Blood 59, 1067-1072
7. Fulcher, C. A., Gardiner, J. H., Griffin, J. H. and Zimmerman, T. S. (1984) Blood 63, 486-489
8. Kalafatis, M., Rand, M. D. and Mann, K. G. (1994) J. Biol. Chem. 269, 31869-31880
9. Kalafatis, M., Bertina, R. M., Rand, M. D. and Mann, K. G. (1995) J. Biol. Chem. 270, 4053-4057
10. Nicolaes, G. A. F., Tans, G., Thomassen, M. C. L. G.D., Hemker, H. C., Pabringer, I., Varadi, K., Schwarz, H. P. and Rosing, J. (1995) J. Biol. Chem. 270, 21158-21166
11. Eaton, D., Rodriguez, H. and Vehar, G. A. (1986) Biochemistry 25, 505-512
12. Fay, P. J., Smudzin, T. M. and Walker, F. J. (1992) J. Biol. Chem. 266, 20139-20145
13. Walker, F. J. (1981) J. Biol. Chem. 256, 11128-11131
14. Rosing, J., Hoekema, L., Nicolaes, G., Thomassen, M. C. L. G.D., Hemker, H. C., Varadi, K., Schwarz, H. P. and Tans, G. (1995) J. Biol. Chem. 270, 27852-27858
15. Heeb, M. J., Westers, R. M., Tans, G., Rosing, J. and Griffin, J. H. (1993) J. Biol. Chem. 268, 2872-2877
16. Heeb, M. J., Rosing, J., Bakker, H. M., Fernandez, J. A., Tans, G. and Griffin, J. H. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 2728-2732
17. Hackeng, T. M., van 't Veer, C., Meijers, J. C. M. and Bouma, B. N. (1994) J. Biol. Chem. 269, 21051-21058
18. van 't Veer, C., Hackeng, T. M., Biesbroek, D., Sixma, J. J. and Bouma, B. N. (1994) Blood 85, 1815-1821
19. Gladson, C. L., Scharrer, I., Hach, V., Beck, K. H. and Griffin, J. H. (1988) Thromb. Haemost. 59, 18-22
20. Nawroth, P. P. and Stern, D. M. (1986) J. Exp. Med. 163, 740-745
21. Nawroth, P. P., Handley, D. A., Esmon, C. T. and Stern, D. M. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 3460-3464
22. Moore, K. L., Andreoli, S. P., Esmon, N. L., Esmon, C. T. and Bang, N. U. (1987) J. Clin. Invest 79, 124-130
23. Moore, K. L., Esmon, C. T. and Esmon, N. L. (1989) Blood 73, 159-165
24. Conway, E. M. and Rosenberg, R. D. (1988) Mol. Cell. Biol. 8, 5588-5592
25. Scarpati, E. M. and Sadler, E. M. (1989) J. Biol. Chem. 264, 20705-20713
26. Taylor, F. B., Chang, A. C. K., Esmon, C. T., D'Angelo, A., Vigano-D'Angelo, S. and Blick, K. (1987) J. Clin. Invest. 79, 918-925
27. Esmon, C. T., Taylor, F. B. and Snow, T. R. (1991) Thromb. Haemost. 66, 160-165
28. Taylor, F. B., Chang, A. C. K., Ferrell, G., Mather, T., Catlett, R., Blick, K. and Esmon, C. T. (1991) Blood 78, 357-363
29. Coalson, J. J., Benjamin, B., Archer, L. T., Beller, B., Gilliam, C. L., Taylor, F. B. and Hinshaw, L. B. (1978) Circ. Shock 5, 423-137
30. Warr, T. A., Rao, V. M. and Rapaport, S. I. (1990) Blood 75, 1481-1489
31. Taylor, F. B., Chang, A. C. K., Peer, G. T., Mather, T., Blick, K., Catlett, R., Lockhart, M. S. and Esmon, C. T. (1991) Blood 78, 364-368
32. Fukudome, K. and Esmon, C. T. (1994) J. Biol. Chem. 269, 26486-26491
33. Koedam, J. A., Meijers, J. C. M., Sixma, J. J. and Bouma, B. N. (1988) J. Clin. Invest. 82, 1236-1243
34. Hackeng, T. M., Hessing, M., van 't Veer, C., Meijer-Huizinga, F., Meijers, J. C. M., de Groot, P. G., van Mourik, J. A. and Bouma, B. N. (1993) J. Biol. Chem. 268, 3993-4000
35. Hessing, M., Kanters, D., Hackeng, T. M. and Bouma, B. N. (1990) Thromb. Haemost. 64, 245-250
36. Kane, W. H. and Majerus, P. W. (1981) J. Biol. Chem. 256, 1002-1007
37. van 't Veer, C., Hackeng, T. M., Delahaye, C., Sixma, J. J. and Bouma, B. N. (1994) Blood 84, 1132-1142
38. Tans, G., Nicolaes, G. A. F., Thomassen, M. C. L. G. D., Hemker, H. C., Zonneveld, A. J., Pannekoek, H. and Rosing, J. (1994) J. Biol. Chem. 269, 15969-15972
39. Jaffe, E. A., Nachman, R. L., Becker, C. G. and Minick, R. (1973) J. Clin. Invest. 52, 2745-2756
40. Willems, C., Astaldi, G. C. B., de Groot, P. G., Janssen, M. C., Gonsalvez, M. D., Zeijlemaker, W. P., van Mourik, J. A. and van Aken, W. G. (1982) Exp. Cell. Res. 139, 191-200
41. Rosing, J., Zwaal, R. F. A. and Tans, G. (1986) J. Biol. Chem. 261, 4224-4228
42. Haley, P. E., Doyle, M. E. and Mann, K. G. (1989) J. Biol. Chem. 264, 16303-16310
43. Solymoss, S., Tucker, M. M. and Tracy, P. B. (1988) J. Biol. Chem. 263, 14884-14890
44. Tans, G., Rosing, J., Thomassen, M. C. L. G. D., Heeb, M. J., Zwaal, R. F. A. and Griffin, J. H. (1991) Blood 77, 2641-2648
45. Bakker, H. M., Tans, G., Janssen-Claessen, T., Thomassen, M. C. L. G. D., Hemker, H. C., Griffin, J. H. and Rosing, J. (1992) Eur. J. Biochem. 208, 171-178
46. Comp, P. C. and Esmon, C. T. (1979) Blood 54, 1272-1281
47. Dahlbäck, B. and Stenflo, J. (1980) Eur. J. Biochem. 107, 331-335
48. Nesheim, M. E., Canfield, W. M., Kisiel, W. and Mann, K. G. (1982) J. Biol. Chem. 257, 1443-1447
49. Hirokawa, K. and Aoki, N. (1990) Biochem. J. 108, 839-845
50. Kapiotis, S., Besemer, J., Bevec, D., Valent, P., Bettelheim, P., Lechner, K. and Speiser, W. (1991) Blood 78, 410-415
51. Tijburg, P. N. M., van Heerde, W. L., Leenhouts, H. M., Hessing, M., Bouma, B. N. and de Groot, P. G. (1990) J. Biol. Chem. 266, 4017-4022
52. Doyle, M. F. and Mann, K. G. (1990) J. Biol. Chem. 265, 10693-10701
53. Wu, Q., Tsiang, M., Lentz, S. R. and Sadler, J. E. (1992) J. Biol. Chem. 267, 7083-7088
54. Côté. H. C. F., Bajzar, L., Stevens, W. K., Samis, J. A., Morser, J., Nesheim, M. E. and MacGillivray, R. T. A. (1995) Blood 86, 72a