Effects on acne of two oral contraceptives containing desogestrel and cyproterone acetate

International Journal of Fertility and Menopausal Studies

Volumn 41, Issue 4, 1996, Pages 423-429

  Charoenvisal, Chalermporn ^a   Thaipisuttikul, Yupin ^a  

^a Chalermporn Clinic   (Thailand)

Author keywords

acne; contraceptives; cyproterone acetate; desogestrel; efficacy; sex hormone binding globulin; testosterone

Indexed keywords

CYPROTERONE ACETATE; DESOGESTREL; DESOGESTREL PLUS ETHINYLESTRADIOL; DIANE; ETHINYLESTRADIOL; ORAL CONTRACEPTIVE AGENT;

ACNE; ADOLESCENT; ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG FORMULATION; FEMALE; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VERTIGO; WEIGHT GAIN;

ACNE; ANDROGENS; ASIA; BIOLOGY; COMPARATIVE STUDIES; CONTRACEPTION; CONTRACEPTIVE AGENTS; CONTRACEPTIVE AGENTS, FEMALE; CONTRACEPTIVE AGENTS, PROGESTIN; CONTRACEPTIVE METHODS--THERAPEUTIC USE; CYPROTERONE ACETATE; DERMATITIS; DESOGESTREL; DEVELOPING COUNTRIES; DISEASES; ENDOCRINE SYSTEM; FAMILY PLANNING; HORMONE ANTAGONISTS; HORMONES; ORAL CONTRACEPTIVES, COMBINED--THERAPEUTIC USE; ORAL CONTRACEPTIVES--THERAPEUTIC USE; PHYSIOLOGY; RESEARCH METHODOLOGY; RESEARCH REPORT; SOUTHEASTERN ASIA; STUDIES; TESTOSTERONE; THAILAND; TREATMENT;

ACNE VULGARIS; ADOLESCENT; ADULT; CONTRACEPTIVES, ORAL, SYNTHETIC; CYPROTERONE ACETATE; DESOGESTREL; FEMALE; HUMANS; PATIENT DROPOUTS; PROGESTERONE CONGENERS; SEX HORMONE-BINDING GLOBULIN; TESTOSTERONE;

EID: 0029802976     PISSN: 10693130     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Lever L, Marks R: Current views on the aetiology, pathogenesis and treatment of acne vulgaris. Drugs 39:681-692, 1990.
2. Lemay A, Dodin Dewailly D, Grenier R, et al: Attenuation of mild hyperandrogenic activity in postpuberal acne by a triphasic oral contraceptive containing low doses of ethynyl estradiol and d,l-norgestrel. J Clin Endocrinol Metab 71:8-14, 1990.
3. Wheeler JM, Malinak LR: Complexion changes in oral contraceptive users. /Reprod Med 36:340-344, 1991.
4. Barranco VP, Jones DD: Effect of oral contraceptives on acne. Southern Med J 67:703-706, 1974.
5. Barranco VP: Effect of androgen-dominant and estrogen-dominant oral contraceptives on acne. Cutis 14:384-386, 1974.
6. Kirk J: Norgestrel and acne. Med J Aust 2:396, 1971.
7. Heber KR: Norgestrel and acne. Med J Aust 2:594, 1971.
8. Vange N van der, Blankenstein MA, Kloosterboer HJ, et al: Effects of seven low-dose combined oral contraceptives on sex hormone binding globulin, corticosteroid binding globulin, total and free testosterone. Contraception 41:345-354, 1990.
9. Eeden C van, Hemelrijk J: A test for the equality of probabilities against a class of specified alternative hypotheses, including trend. Proc Ron Ned Acad Wetensch A58:17, 191, 310, 1955.
10. Aizawa H, Niimura M: Adrenal androgen abnormalities in women with late onset and persistent acne. Arch Dermatol Res 284:451-55, 1993.
11. Newton J: Classification and comparison of oral contraceptives containing new generation progestogens. Hum Reprod Update, 1:231-263, 1995.
12. Bilotta P, Favilli S: Clinical evaluation of a monophasic ethinylestradiol/desogestrel-containing oral contraceptive. Arzneimittelforschung 38:932-934.
13. Geissler KH, Ballmer F: Einfluss einer Kombination von Desogestrel und Ethinylestradiol auf Akne vulgaris bei Frauen mit Kontrazeptionswunsch. Gynäkologie 2:321-324, 1989.
14. Venturoli S, Porcu E, Gammi L, et al: The effects of desogestrel and ethinylestradiol combination in normal and hyperandrogenic young girls: speculations on contraception in adolescence. Acta Eur Fertil 19:129-134, 1988.
15. Palatsi R, Hirvensalo E, Liukko P, et al: Serum total and unbound testosterone and sex hormone binding globulin (SFffiG) in female acne patients treated with two different oral contraceptives. Acta Derm Venereol (Stockh) 64:517-523, 1984.
16. Alien BS, Smith G: Various parameters for grading acne vulgaris. Arch Dermatol 118:23-25, 1982.
17. Carlborg L: Cyproterone acetate versus levonorgestrel combined with ethinyl estradiol in the treatment of acne. Acta Obstet Gynecol Scand 134:29-232, 1986.
18. Colver GB, Mortimer PS, Dawber RPR: Cyproterone acetate and two doses of oestrogen in female acne: a double-blind comparison. Br J Dermatol 118:95-99, 1988.
19. Fugère P, Percival-Smith RKL, Lussier-Cacan S, et al: Cyproterone acetate/ethinyl estradiol in the treatment of acne. A comparative dose-response study of the estrogen component. Contraception 42:225-234, 1990.
20. Lévrier M, Degrelle H, Bestaux Y, et al: Efficacité sur l'acné des contraceptifs oraux. Rev Fr Gynecol Obstet 83:573-576, 1988.
21. Miller JA, Wojnarowska FT, Dowd PM, et al: Antiandrogen treatment in women with acne: a controlled trial. BrJDermatol 114:705-716, 1986.
22. McKenna JT: The use of anti-androgens in the treatment of hirsutism. Clin Endocrinol 35:1-3, 1991.