메뉴 건너뛰기




Volumn 17, Issue 10, 1996, Pages 2267-2269

Influence of a mutation reducing the catalytic activity of the cytochrome P450 CYP2D6 on lung cancer susceptibility

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 ISOENZYME;

EID: 0029802706     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.10.2267     Document Type: Article
Times cited : (17)

References (28)
  • 2
    • 0023954396 scopus 로고
    • Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22
    • Gonzalez, F.J., Vilbois, F., Hardwick, J.P., McBride, O.W., Nebert, D.W., Gelboin, H.V. and Meyer, U.A. (1988) Human debrisoquine 4-hydroxylase (P450IID1): cDNA and deduced amino acid sequence and assignment of the CYP2D locus to chromosome 22. Genomics, 2, 174-179.
    • (1988) Genomics , vol.2 , pp. 174-179
    • Gonzalez, F.J.1    Vilbois, F.2    Hardwick, J.P.3    McBride, O.W.4    Nebert, D.W.5    Gelboin, H.V.6    Meyer, U.A.7
  • 3
    • 0024796958 scopus 로고
    • Human debrisoquine 4-hydroxylase (CYP2D) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene
    • Kimura, S., Umeno, M., Skoda, R.C., Meyer, U.A. and Gonzalez, F.J. (1989) Human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene. Am. J. Hum. Genet., 45, 889-904.
    • (1989) Am. J. Hum. Genet. , vol.45 , pp. 889-904
    • Kimura, S.1    Umeno, M.2    Skoda, R.C.3    Meyer, U.A.4    Gonzalez, F.J.5
  • 4
    • 0025848338 scopus 로고
    • A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6
    • Crespi, C.L., Penman, B.W., Gelboin, H.V. and Gonzalez, F.J. (1991) A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6. Carcinogenesis, 12, 1197-1201.
    • (1991) Carcinogenesis , vol.12 , pp. 1197-1201
    • Crespi, C.L.1    Penman, B.W.2    Gelboin, H.V.3    Gonzalez, F.J.4
  • 6
    • 0027464041 scopus 로고
    • Relationship between personality and debrisoquine hydroxylation capacity. Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6
    • Llerena, A., Edman, G., Cobaleda, J., Benitez, J., Schalling, D. and Bertilsson, L. (1993) Relationship between personality and debrisoquine hydroxylation capacity. Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6. Acta Psychiat. Scand., 87, 23-28.
    • (1993) Acta Psychiat. Scand. , vol.87 , pp. 23-28
    • Llerena, A.1    Edman, G.2    Cobaleda, J.3    Benitez, J.4    Schalling, D.5    Bertilsson, L.6
  • 7
    • 0027319640 scopus 로고
    • Are poor metabolizers of sparteine/debrisoquine less pain tolerant than extensive metabolizers
    • Sindrup, S.H., Poulsen, L., Brøsen, K., Arendt-Nielsen, L. and Gram, L.F. (1993) Are poor metabolizers of sparteine/debrisoquine less pain tolerant than extensive metabolizers. Pain, 53, 335-339.
    • (1993) Pain , vol.53 , pp. 335-339
    • Sindrup, S.H.1    Poulsen, L.2    Brøsen, K.3    Arendt-Nielsen, L.4    Gram, L.F.5
  • 8
    • 0345638787 scopus 로고
    • Two mutant alleles of the human cytochrome P-450db1 gene (P450C2D1) associated with genetically deficient metabolism of debrisoquine and other drugs
    • Skoda, R.C., Gonzalez, F.J., Demierre, A. and Meyer, U.A. (1988) Two mutant alleles of the human cytochrome P-450db1 gene (P450C2D1) associated with genetically deficient metabolism of debrisoquine and other drugs. Proc. Natl Acad. Sci. USA, 85, 5240-5243.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 5240-5243
    • Skoda, R.C.1    Gonzalez, F.J.2    Demierre, A.3    Meyer, U.A.4
  • 10
    • 0026033923 scopus 로고
    • Polymorphism of human CYP2D genes involved in drug metabolism: Possible relationship to individual cancer risk
    • Nebert, D.W. (1991) Polymorphism of human CYP2D genes involved in drug metabolism: possible relationship to individual cancer risk. Cancer Cells, 3, 93-96.
    • (1991) Cancer Cells , vol.3 , pp. 93-96
    • Nebert, D.W.1
  • 11
    • 0028961525 scopus 로고
    • Genetic polymorphism and cancer susceptibility: Fourteenth Sapporo Cancer Seminar
    • Gonzalez, F.J. (1995) Genetic polymorphism and cancer susceptibility: Fourteenth Sapporo Cancer Seminar. Cancer Res., 55, 710-715.
    • (1995) Cancer Res. , vol.55 , pp. 710-715
    • Gonzalez, F.J.1
  • 13
    • 0025080352 scopus 로고
    • Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification
    • Heim, M. and Meyer, U.A. (1990) Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification. Lancet, 336, 529-532.
    • (1990) Lancet , vol.336 , pp. 529-532
    • Heim, M.1    Meyer, U.A.2
  • 15
    • 0025840237 scopus 로고
    • Detection of DNA sequence polymorphisms in carcinogen metabolism genes by polymerase chain reaction
    • Bell, D.A. (1991) Detection of DNA sequence polymorphisms in carcinogen metabolism genes by polymerase chain reaction. Environ. Mol. Mutagen., 18, 245-248.
    • (1991) Environ. Mol. Mutagen. , vol.18 , pp. 245-248
    • Bell, D.A.1
  • 16
    • 0025950370 scopus 로고
    • Debrisoquine/sparteine hydroxylation genotype and phenotype: Analysis of common mutations and alleles of CYP2D6 in a European population
    • Broly, F., Gaedigk, A., Heim, M., Eichelbaum, M., Morike, K. and Meyer, U.A. (1991) Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population. DNA Cell Biol. 8, 545-558.
    • (1991) DNA Cell Biol. , vol.8 , pp. 545-558
    • Broly, F.1    Gaedigk, A.2    Heim, M.3    Eichelbaum, M.4    Morike, K.5    Meyer, U.A.6
  • 17
    • 0026240145 scopus 로고
    • Identification of a new variant CYP2D6 allele lacking the codon encoding Lys-281: Possible association with the poor metabolizer phenotype
    • Tyndale, R., Aoyama, T., Broly, F., Matsunaga, T., Inaba, T., Kalow, W., Gelboin, H.V., Meyer, U.A. and Gonzalez, F.J. (1991) Identification of a new variant CYP2D6 allele lacking the codon encoding Lys-281: possible association with the poor metabolizer phenotype. Pharmacogenetics, 1, 26-32.
    • (1991) Pharmacogenetics , vol.1 , pp. 26-32
    • Tyndale, R.1    Aoyama, T.2    Broly, F.3    Matsunaga, T.4    Inaba, T.5    Kalow, W.6    Gelboin, H.V.7    Meyer, U.A.8    Gonzalez, F.J.9
  • 18
    • 0026776502 scopus 로고
    • Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility
    • Wolf, C.R., Smith, C.A.D., Gough, A.C. et al. (1992) Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility. Carcinogenesis, 13, 1035-1038.
    • (1992) Carcinogenesis , vol.13 , pp. 1035-1038
    • Wolf, C.R.1    Smith, C.A.D.2    Gough, A.C.3
  • 20
    • 0027756769 scopus 로고
    • New opportunities in cancer risk evaluation using PCR-based DNA analysis for CYP2D6
    • Idle, J.R. and Daly, A.K. (1993) New opportunities in cancer risk evaluation using PCR-based DNA analysis for CYP2D6. Environ. Health Perspect., 101 (Suppl. 3), 117-120.
    • (1993) Environ. Health Perspect. , vol.101 , Issue.3 SUPPL. , pp. 117-120
    • Idle, J.R.1    Daly, A.K.2
  • 23
    • 0027273757 scopus 로고
    • Debrisoquine oxidation polymorphism: Phenotypic consequences of a 3-base-pair deletion in exon 5 of the CYP2D6 gene
    • Broly, F. and Meyer, U.A. (1993) Debrisoquine oxidation polymorphism: phenotypic consequences of a 3-base-pair deletion in exon 5 of the CYP2D6 gene. Pharmacogenetics, 3, 123-130.
    • (1993) Pharmacogenetics , vol.3 , pp. 123-130
    • Broly, F.1    Meyer, U.A.2
  • 24
    • 0029622336 scopus 로고
    • An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis
    • Broly, F., Marez, D., Sabbagh, N., Legrand, M., Millecamps, S., Lo-Guidice, J.M., Boone, P. and Meyer, U.A. (1995) An efficient strategy for detection of known and new mutations of the CYP2D6 gene using single strand conformation polymorphism analysis. Pharmacogenetics, 5, 373-384.
    • (1995) Pharmacogenetics , vol.5 , pp. 373-384
    • Broly, F.1    Marez, D.2    Sabbagh, N.3    Legrand, M.4    Millecamps, S.5    Lo-Guidice, J.M.6    Boone, P.7    Meyer, U.A.8
  • 26
    • 0028806579 scopus 로고
    • A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency
    • Broly, F., Marez, D., Lo Guidice, J.M., Sabbagh, N., Legrand, M., Boone, P. and Meyer, U.A. (1995) A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency. Hum. Genet., 96, 601-603.
    • (1995) Hum. Genet. , vol.96 , pp. 601-603
    • Broly, F.1    Marez, D.2    Lo Guidice, J.M.3    Sabbagh, N.4    Legrand, M.5    Boone, P.6    Meyer, U.A.7
  • 27
    • 0028826569 scopus 로고
    • A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype
    • Marez, D., Sabbagh, N., Legrand, M., Lo-Guidice, J.M., Boone, P. and Broly, F. (1995) A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype. Pharmacogenetics, 5, 305-311.
    • (1995) Pharmacogenetics , vol.5 , pp. 305-311
    • Marez, D.1    Sabbagh, N.2    Legrand, M.3    Lo-Guidice, J.M.4    Boone, P.5    Broly, F.6
  • 28
    • 0029937877 scopus 로고    scopus 로고
    • An additional allelic variant of the CYP2D6 gene causing impaired metabolism of sparteine
    • Marez, D., Legrand, M., Sabbagh, N., Lo-Guidice, J.M., Boone, P. and Broly, F. (1996) An additional allelic variant of the CYP2D6 gene causing impaired metabolism of sparteine. Hum. Genet., 97, 668-670.
    • (1996) Hum. Genet. , vol.97 , pp. 668-670
    • Marez, D.1    Legrand, M.2    Sabbagh, N.3    Lo-Guidice, J.M.4    Boone, P.5    Broly, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.