Regulation of GM-CSF gene transcription by core-binding factor

Cell Growth and Differentiation

Volumn 7, Issue 7, 1996, Pages 917-922

  Cockerill, Peter N ^a   Osborne, Cameron S ^a   Bert, Andrew G ^a   Grotto, Rina J M ^a  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; TRANSCRIPTION FACTOR;

ARTICLE; CELL DIFFERENTIATION; ENHANCER REGION; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE LOCATION; GENE LOCUS; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTO ONCOGENE; T LYMPHOCYTE; TRANSCRIPTION REGULATION;

BASE SEQUENCE; BINDING SITES; CELL LINE; CORE BINDING FACTORS; DNA-BINDING PROTEINS; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; PROMOTER REGIONS (GENETICS); SEQUENCE ANALYSIS, DNA; T-LYMPHOCYTES; TRANSCRIPTION FACTORS;

EID: 0029802364     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Gasson, J. C. Molecular physiology of granulocyte-macrophage colony-stimulating factor. Blood, 77: 1131-1145, 1991.
2. Masuda, E. S., Naito, Y. T., Arai, K., and Arai, N. Expression of lymphokine genes. Immunologist, 1: 198-203, 1993.
3. Russel, N. H. Autocrine growth factors and leukemic haemopoiesis. Blood Rev., 6: 149-156, 1992.
4. Begley, G., Metcalf, D., and Nicola, N. A. Purified colony stimulating factors (G-CSF and GM-CSF) induce differentiation in human HL60 leukemic cells with suppression of clonogenicity. Int. J. Cancer, 39: 99-105, 1987.
5. Bassan, R., Rambaldi, A., Amaru, R., Motta, T., and Barbui, T. Unexpected remission of acute myeloid leukemia after GM-CSF. Br. J. Haematol., 87: 835-838, 1994.
6. Jenkins, F., Cockerill, P. N., Bohmann, D., and Shannon, M. F. Multiple signals are required for function of the human granulocyte-macrophage colony-stimulating factor gene promoter in T cells. J. Immunol., 155: 1240-1251, 1995.
7. Tsuboi, A., Muramatsu, M., Tsutsumi, A., Arai, K., and Aral, N. Calcineurin activates transcription from the GM-CSF promoter in synergy with either protein kinase C or NF-kB/AP-1 in T cells. Biochem. Biophys. Res. Commun., 199:1064-1072, 1994.
8. Nimer, S. D., Morita, E. A., Martis, M. J., Wachsman, W., and Gasson, J. C. Characterization of the human granulocyte-macrophage colonystimulating factor promoter region by genetic analysis: correlation with DNasel footprinting. Mol. Cell. Biol., 8: 1979-1984, 1988.
9. Cockerill, P. N., Shannon, M. F., Bert, A. G., Ryan, G. R., and Vadas, M. A. The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer. Proc. Natl. Acad. Sci. USA, 90: 2466-2470, 1993.
10. Cockerill, P. N., Bert, A. G., Jenkins, F., Ryan, G. R., Shannon, M. F., and Vadas, M. A. Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c. Mol. Cell. Biol., 15: 2071-2079, 1995.
11. Osbome, C. S., Vadas, M. A., and Cockerill, P. N. Transcriptional regulation of mouse granulocyte-macrophage colony-stimulating factor/ IL-3 locus. J. Immunol., 155: 226-235, 1995.
12. Himes, S. R., Coles, L. S., Katsikeros, R., Lang, R. K., and Shannon, M. F. HTLV-1 tax activation of the GM-CSF and G-CSF promoters requires the interaction of NF-kB with other transcription factor families. Oncogene, 8: 3189-3197, 1993.
13. Masuda, E. S., Yamaguchi-lwai, Y., Tsuboi, A., Hung, P., Arai, K., and Arai, N. The transcription factor Sp1 is required for induction of the murine GM-CSF promoter in T cells. Biochem. Biophys. Res. Commun., 205: 1518-1525, 1994.
14. Kaushansky, K. Control of granulocyte-macrophage colony-stimulating factor production in normal endothelial cells by positive and negative regulatory elements. J. Immunol., 143: 2525-2529, 1989.
15. Jianping, Y., Young, H. A., Ortaldo, J. R., and Ghosh, P. Identification of a DMA binding site for the nuclear factor YY1 in the human GM-CSF core promoter. Nucleic Acids Res., 22: 5672-5678, 1994.
16. Nimer, S., Fraser, J., Richards, J., Lynch, M., and Gasson, J. The repeated sequence CATT(A/T) is required for granulocyte-macrophage colony-stimulating factor promoter activity. Mol. Cell. Biol., 10: 6084-6088, 1990.
17. Redondo, J. M., Pfohl, J. L, Hemandez-Munain, C., Wang, S., Speck, N. A., and Krangel, M. S. Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor 8 and murine leukemia virus enhancers. Mol. Cell. Biol., 12: 4817-4823, 1992.
18. Cameron, S., Taylor, D. S., TePas, E. C., Speck, N. A., and Mathey-Prevot, B. Identification of a critical regulatory site in the human interleukin-3 promoter by in vivo footprinting. Blood, 83: 2851-2859, 1994.
19. Zhang, D., Fujioka, K., Hetherington, C. J., Shapiro, L. H Chen, H., Look, A. T., and Tenen, D. G. Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colonystimulating factor) receptor promoter and binds PEBP2/CBF (AML1 ). Mol. Cell. Biol., 14: 8085-8095, 1994.
20. Tanaka, T., Tanaka, K., Ogawa, S., Kurokawa, M., Mitani, K., Nishida, J., Shibata, Y., Yazaki, Y., and Hirai, H. An acute myeloid leukemia gene, AML1, regulates myeloid cell differentiation and transcriptional activation antagonistically by two alternatively spliced forms. EMBO J., 14:341 -350, 1995.
21. Meyers, S., Lenny, N., and Hiebert, S. W. The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation. Mol. Cell. Biol., 15: 1974-1982, 1995.
22. Liu, P., Tarle, S. A., Hajra, A., Claxton, D. F., Marlton, P., Freedman, M., Siciliano, M. J., and Collins, F. S. Fusion between transcription factor CBFβ/PEBP2β and a myosin heavy chain in acute myeloid leukemia. Science (Washington DC), 261:1041-1044, 1993.
23. Kaushansky, K., O'Hara, P. J., Berkner, K., Segal, G. M., Hagen, F. S., and Adamson, J. W. Genomic cloning, characterization, and multilineage growth-promoting activity of human granulocyte-macrophage colonystimulating factor. Proc. Natl. Acad. Sci. USA, 83: 3101-3105, 1986.
24. Golemis, E. A., Speck, N. A., and Hopkins, N. Alignment of U3 region sequences of mammalian type C viruses: identification of highly conserved motifs and implications for enhancer design. J. Virol., 64:534-542, 1990.
25. Nimer, S., Uchida, H., Zhang, J., Hiebert, S., Meyers, S., and Frank, R. AML1/ETO can block transactivation of the GM-CSF promoter by AML1 B. 9th Symposium on the Molecular Biology of Hematopoiesis. Acta Haematol. 93: 168, 1995.
26. Takahashi, A., Satake, M., Yamaguchi-lwai, Y., Bae, S. C., Lu, J., Maruyama, M., Zhang, Y. W., Oka, H., Arai, N., Arai, K., and Ito, Y. Positive and negative regulation of granulocyte-macrophage colony-stimulating factor promoter activity by AML1-related transcription factor, PEPB2. Blood, 86: 607-616, 1995.
27. Heusohn, F., Pohler, U., Decker, T., Just, U., Ostertag, W., Lohmann-Matthes, M., and Baccarini, M. Coordinate expression of the lineagespecific growth factor colony-stimulating factor (CSF)-1 and its receptor selectively promotes macrophage maturation during differentiation of multipotential progenitor cells. Cell Growth & Differ., 5: 1119-1126, 1994.