Serum markers for Down's syndrome in relation to number of previous births and maternal age

Prenatal Diagnosis

Volumn 16, Issue 8, 1996, Pages 699-703

  Wald, N J ^a   Watt, H C ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

Down's syndrome; Maternal age; Parity; Prenatal screening

Indexed keywords

ALPHA FETOPROTEIN; CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN ALPHA SUBUNIT; CHORIONIC GONADOTROPIN BETA SUBUNIT; ESTRIOL; INHIBIN;

ADOLESCENT; ADULT; ARTICLE; BODY WEIGHT; DOWN SYNDROME; ETHNIC GROUP; FEMALE; GESTATIONAL AGE; HUMAN; HUMAN EXPERIMENT; MATERNAL AGE; NORMAL HUMAN; PARITY; PRENATAL SCREENING; PRIORITY JOURNAL;

ADOLESCENT; ADULT; ALPHA-FETOPROTEINS; BIOLOGICAL MARKERS; BODY WEIGHT; CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; CONTINENTAL POPULATION GROUPS; DOWN SYNDROME; ESTRIOL; FEMALE; GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; HUMANS; INHIBINS; MATERNAL AGE; PARITY; PREGNANCY; PREGNANCY, HIGH-RISK; PRENATAL DIAGNOSIS;

EID: 0029802246     PISSN: 01973851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0223(199608)16:8<699::AID-PD919>3.0.CO;2-P     Document Type: Article

References (13)

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3. Haddow, J.E., Palomaki, G.E., Knight, G.J. (1995). Effect of parity on human chorionic gonadotrophin levels and Down's syndrome screening, J. Med. Screening, 2, 28-30.
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5. Obiekwe, B.C., Chard, T. (1982). Human chorionic gonadotrophin levels in maternal blood in late pregnancy: relation to birth weight, sex, and condition of the infant at birth, Br. J. Obstet. Gynaecol., 89, 543-546.
6. Palomaki, G.E., Knight, G.J., Haddow, J.E., Canick, J.A., Wald, N.J., Kennard, A. (1993). Cigarette smoking and levels of maternal serum alpha-fetoprotein, unconjugated estriol, and human chorionic gonadotropin: impact on Down syndrome screening, Obstet. Gynecol., 81, 675-678.
7. Spencer, K. (1995). The influence of gravidity in Down's syndrome screening with free β-hCG, Prenat. Diagn., 15, 87-89.
8. Wald, N.J., Cuckle, H.S., Densem, J.W., Nanchahal, K., Canick, J.A., Haddow, J.E., Knight, G.J., Palomaki, G.E. (1988a). Maternal serum unconjugated oestriol as an antenatal screening test for Down's syndrome, Br. J. Obstet. Gynaecol., 95, 334-341.
9. Wald, N.J., Cuckle, H.S., Densem, J.W., Nanchahal, K., Royston, P., Chard, T., Haddow, J.E., Knight, G.J., Palomaki, G.E., Canick, J.A. (1988b). Maternal serum screening for Down's syndrome in early pregnancy, Br. Med. J., 297, 883-887.
10. Wald, N.J., Kennard, A., Densem, J.W., Cuckle, H.S., Chard, T., Butler. L. (1992). Antenatal maternal serum screening for Down's syndrome: results of a demonstration project, Br. Med. J., 305, 391-394.
11. Wald, N.J., Densem, J.W., Smith, D., Klee, G.G. (1994). Four marker serum screening for Down's syndrome, Prenat. Diagn., 14, 707-716.
12. Wald, N.J., Densem, J.W., George, L., Muttukrishna, S., Knight P.G. (1996). Prenatal screening for Down's syndrome using inhibin-A as a serum marker, Prenat. Diagn. 16, 143-153.
13. Watt, H., Wald, N.J., Smith, D., Kennard, A., Densem, J. (1996). Serum markers for Down's syndrome in different ethnic groups. In press.