Efficacy and safety of rifabutin in the treatment of patients with newly diagnosed pulmonary tuberculosis

American Journal of Respiratory and Critical Care Medicine

Volumn 154, Issue 5, 1996, Pages 1462-1467

  Mcgrecor, Maureen M ^b   Olliaro, Piero ^b   Wolmarans, Liesel ^b   Mabuza, Bafana ^b   Bredell, Marie ^b   Felten, Michael K ^b   Fourie, P Bernard ^a  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ETHAMBUTOL; ISONIAZID; RIFABUTIN; RIFAMPICIN;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HUMAN; LEUKOPENIA; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM TUBERCULOSIS; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RASH; THROMBOCYTOPENIA; TREATMENT OUTCOME;

EID: 0029802173     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.154.5.8912765     Document Type: Article

References (19)

1. Grosset, J. H. 1988. New approaches in antimycobacterial chemotherapy. Drugs Today 24(5):291-301.
2. Mitchison, D. A., G. A. Ellard, and J. H. Grosset. 1988. New antimycobacterial drugs for the treatment of mycobacterial disease in man. Br. Med. Bull. 44(3):757-774.
3. Truffot-Pernot, C., A. M. Giroir, L. Majry, and J. Grosset. 1988. Etude des concentrations minimaux inhibitrices de la rifabutine (ansamycine LM 427) pour Mycobacterium avium-intracellulare. Rev. Mal. Respir. 58(4):401-406.
4. O'Brien, R. J., M. A. Lyle, and D. E. Snider. 1987. Rifabutin(ansamycin LM 427): A new rifamycin-S derivative for the treatment of mycobacterial diseases. Rev. Infect. Dis. 9:519-530.
5. Strolin Benedetti, M., C. Efthymiopoulos, D. Sassella, E. Moro, and M. Repetto. 1990. Autoinduction of rifabutin metabolism in man. Xenobiotica 20(11):1113-1119.
6. Mozzi, E., R. Germiniani, G. Cantalupi, V. Marchetti, M. P. Vettaro, and A. Sardi. 1983. Human pharmacokinetics of LM 427, a new antimycobacterial agent: Tissue distribution and excretion. 13th ICC-International Congress of Chemotherapy, Vienna. 28 August-2 September.
7. Ungheri, D., and A. Sanfilippo. 1986. Activity of LM 427 on Legionella spp: in vitro study and intracellular killing. In J. Ishigami, editor. Recent Advances in Chemotherapy. University Tokyo Press, Tokyo. 1919-1920.
8. Van Der Awera, P., T. Matsumoto, and M. Husson. 1988. Intraphagocytic penetration of antibiotics. J. Antimicrob. Chemother. 22(2): 185-192.
9. Mancini, P., F. Pasqua, L. Mazzei, P. Olliaro. 1992. Rifabutin treatment for tuberculosis in patients with liver function abnormalities (letter). J. Antimicrob. Chemother. 30:242.
10. World Health Organization. 1993. Treatment of tuberculosis: guidelines for national programmes. World Health Organization, Geneva.
11. Ji, B., C. Truffot-Pernot, C. LaCroix, M. C. Raviglione, R. J. O'Brien, P. Olliaro, G. Roscigno, and J. Grosset. 1993. Effectiveness of rifampin, rifabutin, and rifapentine for preventive therapy of tuberculosis in mice. Am. Rev. Respir. Dis. 148:1541-1546.
12. Jabes, D., C. Delia Bruna, R. Rossi, and P. Olliaro. 1994. Effectiveness of rifabutin alone or in combination with isoniazid in the preventative therapy of mouse tuberculosis. Antimicrob. Agents Chemother. 38:2346-2350.
13. Gonzalez-Montaner, L. J., S. Natal, P. Yonchaiyud, and P. Olliaro. 1994. Rifabutin for the treatment of newly-diagnosed pulmonary tuberculosis: a multinational, randomized, comparative study versus rifampicin. Tuber. Lung Dis. 75:341-347.
14. Bellin, E. 1994. Failure of tuberculosis control. A prescription for change. J. Am. Med. Assoc. 271:708-709.
15. Barnes, P. F., and S. A. Barrows. 1993. Tuberculosis in the 1990s. Ann. Intern. Med. 119:400-410.
16. Davidson, P. T., and H. Q. Le. 1992. Drug treatment of tuberculosis - 1992. Drugs 43:651-673.
17. Addington, W. W. 1979. Patient compliance: the most serious remaining problem in the control of tuberculosis in the United States. Chest 76(Suppl.):741-743.
18. Snider, D. E., Jr., and W. L. Roper. 1992. The new tuberculosis. N. Engl. J. Med. 326:703-705.
19. Mitchison, D. A. 1993. Assessment of new sterilizing drugs for treating pulmonary tuberculosis by culture at 2 months (correspondence). Am. Rev. Respir. Dis. 147:1062-1063.