Regulation of metallothionein gene expression. Studies in transfected primary cultures of chick embryo liver cells

Biochimie

Volumn 78, Issue 4, 1996, Pages 236-244

  Hong Lu, T ^a   Pepe, J ^a   Lambrecht, R W ^a   Bonkovsky, H L ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Chloramphenicol acetytransferase; Heme; Metallothionein gene; Sodium arsenite; Transition metals; galactosidase

Indexed keywords

ARSENITE SODIUM; BETA GALACTOSIDASE; CADMIUM; CHLORAMPHENICOL ACETYLTRANSFERASE; COBALT; HEME OXYGENASE; LUCIFERASE; METALLOTHIONEIN; ZINC;

ANIMAL CELL; ARTICLE; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; LIVER CELL; NONHUMAN; PROMOTER REGION; REPORTER GENE; SIMIAN VIRUS 40;

ANIMALIA; BACTERIA (MICROORGANISMS); SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0029802075     PISSN: 03009084     EISSN: None     Source Type: Journal    
DOI: 10.1016/0300-9084(96)82186-9     Document Type: Article

References (47)

1. 1 Hamer D (1986) Metallothionein. Annu Rev Biochem 55, 913-951
2. 2 Palmiter RD (1987) Molecular biology of metallothionein gene expression. Experientia 52, 81-107
3. 3 Dunn MA, Blalock TL, Cousins RJ (1987) Metallothionein. Proc Soc Exp Biol Med 185, 107-109
4. 4 Andrews GK (1990) Regulation of metallothionein gene expression. Progr Food Nutrition Sci 14, 193-258
5. 5 Kagi JH (1991) Overview of metallothionein. Methods Enzymol 205, 613-626
6. 6 Palmiter RD, Sandgren EP, Koeller DM, Brinster RL (1993) Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice. Mol Cell Biol 13, 5266-5275
7. 7 Wei D, Andrews GK (1988) Molecular cloning of chicken metallothionein. Deduction of the complete amino acid sequence and analysis of expression using cloned cDNA. Nucleic Acids Res 16, 537-553
8. 8 Iijima Y, Fukushima T, Bhuiyan LA, Yamada T, Kosaka F, Sato JD (1990) Synergistic and additive induction of metallothionein in Chang liver cells: A possible mechanism of marked induction of metallothionein by stress. FEBS Lett 269, 218-220
9. 9 Bauman JW, Liu J, Liu YP, Klaassen CD (1991) Increase in metallothionein produced by chemicals that induce oxidative stress. Toxicol Appl Pharmacol 110, 347-354
10. 10 Sato M, Bremner I (1993) Oxygen free radicals and metallothionein. Free Radical Biol Med 14, 325-337
11. 11 Kikuchi G, Yoshida T (1983) Function and induction of the microsomal heme oxygenase. Mol Cell Biol 53/54, 163-183
12. 12 Maines MD (1988) Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. Faseb J 2, 2557-2568
13. 13 Lincoln BC, Healey JF, Bonkovsky HL (1988) Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals. Biochem J 250, 189-196
14. 14 Tyrrell RM, Applegate LA, Tromvoukis Y (1993) The proximal promoter region of the human heme oxygenase gene contains elements involved in stimulation of transcriptional activity by a variety of agents including oxidants. Carcinogenesis 14, 761-765
15. 15 Alam J, Smith A (1992) Heme-hemopexin-mediated induction of metallothionein gene expression. J Biol Chem 267, 16379-16384
16. 16 Gildemeister OS, Pepe JA, Lambrecht RW, Bonkovsky HL (1995) Induction of metallothionein mRNA by iron in hepatocyte cultures. (Abstract) 5th Conference of Int Assoc For Study of Disorders of Iron Metabolism, Boston, MA
17. 17 Dalton T, Palmiter RD, Andrews GK (1994) Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements. Nucleic Acids Res 22, 5016-5023
18. 18 Sequin C, Prevost J (1988) Detection of a nuclear protein that interacts with a metal regulatory element of the mouse metallothionein I gene. Nucleic Acids Res 16, 10547-10560
19. 19 Koizumi S, Suzuki K, Otsuka F (1992) A nuclear factor that recognizes the metal-responsive elements of human metallothionein IIA gene. J Biol Chem 267, 18659-18664
20. 20 Labbe S, Larouche L, Maihot D, Sequin C (1993) Purification of mouse MEP-1, a nuclear protein which binds to the metal regulatory elements of genes encoding metallothionein. Nucleic Acids Res 21, 1549-1554
21. 21 Palmiter RD (1994) Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with aconstitutively active transcription factor, MTF-1. Proc Natl Acad Sci USA 91, 1219-1223
22. 22 Granick S (1966) The induction in vitro of the synthesis of ∂-aminolevulinic acid synthetase in chemical porphyria: a response to certain drugs, sex hormones, and foreign chemicals. J Biol Chem 241, 1359-1375
23. 23 Granick S, Sinclair PR, Sassa S, Grieninger G (1975) Effects by heme, insulin and serum albumin on heme and protein synthesis in chick embryo liver cells cultured in a chemically defined medium, and a spectrofluorometric assay for porphyrin composition. J Biol Chem 250, 9215-9225
24. 24 Bonkovsky HL, Healey JF, Lincoln B, Bacon BR, Bishop DF, Elder GH (1987) Hepatic heme synthesis in a new model of experimental hemochromatosis: studies in rats fed finely divided elemental iron. Hepatology 7, 1195-1203
25. 25 Bonkovsky HL, Healey JF, Lincoln B, Bacon B, Bishop DF (1988) Decreased hepatic 5-aminolevulinate dehydrase in experimental hemochromatosis. Ann NY Acad Sci 526, 365-368
26. 26 Bonkovsky HL, Healey JF, Evans C-O, Brown KA, Wilkinson KD (1989) The hepatic heat shock response: Activiation of ubiquitin-mediated pathways for cell protein breakdown without induction of heme oxygenase in cultured liver cells. Gastroenterology 95, A578 (Abstract)
27. 27 Cable EE, Cable JW, Bonkovsky HL (1993) Repression of hepatic ∂-aminolevulinate synthase by heme and metalloporphyrins: relationship to inhibition of heme oxygenase. Hepatology 18, 119-127
28. 28 Cable EE, Pepe JA, Karamitsios NC, Lambrecht RW, Bonkovsky HL (1994) Differential effects of metalloporphyrins on messenger RNA levels of d-aminolevulinate synthase and heme oxygenase. J Clin Invest 93, 649-654
29. 29 Srivastava KK, Cable EE, Donohue SE, Bonkovsky HL (1993) Molecular basis for heme-dependent induction of heme oxygenase in primary cultures of chick hepatocytes: Demonstration of acquired refractoriness to heme. Eur J Biochem 213, 909-917
30. 30 Lambrecht RW, Cable JW, Pepe JA, Bonkovsky HL (1994) 3,5,5-Trimethylhexanoylferrocene induction of heme oxygenase activity in normal hepatocytes. Biochem Pharmacol 47, 1669-1676
31. 31 Russo SM, Pepe JA, Cable EE, Lambrecht RW, Bonkovsky HL (1994) Synergistic repression of ALA synthase by heme and zinc-mesoporphyrin in a chick embryo liver cell culture model of acute porphyria. Eur J Clin Invest 24, 406-415
32. 32 Fernando LP, Wei D, Andrews GK (1989) Structure and expression of chicken metallothionein. J Nutrion 119, 309-318
33. 33 Pelham H (1985) Activation of heat-shock gene in eukaryotes. Trends Gen 1, 31-35
34. 34 Luce MC, Cristofalo VJ (1992) Reduction of heat shock gene expression correlates with increased thermosensitivity in senescent human fibroblasts. Exp Cell Res 202, 9-16
35. 35 Dubois MF, Bellier S, Seo SJ, Bensaude O (1995) Phosphorylation of the RNA polymerase II largest subunit during heat shock and inhibition of transcription in HeLa cells. J Cell Physiol 158, 417-426
36. 36 Lu TH, Cable EE, Pepe J, Lambrecht RW, Dalton T, Andrews G, Bonkovsky HL (1994) Regulation of hepatic metallothionein (MT) gene expression. Studies in transfected primary liver cell cultures. Hepatology 20, 227A (Abstract)
37. 37 Fernando LP, Andrews GK (1989) Cloning and expression of an avian metallothionein-encoding gene. Gene 81, 177-183
38. 38 Sambrook J, Fritsch EF, Maniatis T (1989) In: Molecular cloning. A laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
39. 39 Cable E, Greene Y, Healey J, Evans CO, Bonkovsky H (1990) Mechanism of synergistic induction of hepatic heme oxygenase by glutethimide and iron: studies in cultured chick embryo liver cells. Biochem Biophys Res Commun 168, 176-181
40. 40 Kingston RE, Chen CA, Okayama H (1993) In: Current Protocols in Molecular Biology (Ausubel RN, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, eds) Green and Wiley Interscience, New York, 9.1.1-9.1.9
41. 41 Pasco DS, Pagan JB (1989) Laboratory methods: Efficient DNA-mediated gene transfer into primary cultures of adult rat hepatocytes. DNA 8, 535-541
42. 42 Brasier AR (1993) In: Current Protocols in Molecular Biology (Ausubel RN, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, eds) Green and Wiley Interscience, New York, 9.6.10-9.6.14
43. 43 Bonkovsky HL, Healey JF, Pohl J (1990) Purification and characterization of heme oxygenase from chick liver - Comparison of the avian and mammalian enzymes. Eur J Biochem 189, 155-166
44. 44 Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Oison BJ, Klenk DC (1985) Measurement of protein using bicinchoninic acid. Anal Biochem 150, 76-85
45. 45 Kioka N, Yamano Y, Komano T, Ueda K (1992) Heat-shock responsive elements in the induction of the multidrug resistance gene (MDR1). FEBS Lett 301, 37-40
46. 46 Alam J, Smith A (1992) Heme-hemopexin mediated induction of metallothionein gene expression. FASEB J 6, A71-(#408) (Abstract)
47. 47 Zhang L, Bermingham-McDonogh O, Turcotte B, Guarente L (1993) Antibody-promoted dimerization bypasses the regulation of DNA binding by the heme domain of the yeast transcriptional activator HAP1. Proc Natl Acad Sci USA 90, 2851-2855