Effect of diacerheine on an experimental post-contusive rabbit model with arthrosis;La diacerheine administree 'curativement' dans un modele experimental d'arthrose post-contusive chez le lapin

Revue du Praticien

Volumn 46, Issue 19 SUPPL., 1996, Pages

  Mazières, Bernard ^a   Blanckaert, Anne ^a   Thiéchart, Michèle ^a   Viguier, Gisèle ^a  

^a CHU RANGUEIL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROPROTECTIVE AGENT; COLLAGENASE; DIACETYLRHEIN; ANTHRAQUINONE DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; HISTOLOGY; NONHUMAN; OSTEOARTHRITIS; RABBIT; ANIMAL; ARTICLE; CARTILAGE; CONTUSION; DISEASE MODEL; ENZYMOLOGY; PATHOLOGY;

ANIMALS; ANTHRAQUINONES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARTILAGE; COLLAGENASES; CONTUSIONS; DISEASE MODELS, ANIMAL; OSTEOARTHRITIS; RABBITS;

EID: 0029801892     PISSN: 00352640     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (6)

1. Mazières B. Utilisation d'un score histologique d'arthrose pour évaluer l'activité de médicaments «anti-arthrosiques». In: Simon L. Loyau G (eds). L'arthrose: perspectives et réalités. Paris: Masson, 1986: 263-6.
2. Gédéon P, Mazières B, Ficat P. Un nouveau modèle d'arthrose expérimentale: la contusion du cartilage. Rev Rhum 1978; 45: 401-8.
3. Mazières B, Blanckaert A, Thiechart M. Experimental post-contusive osteoarthritis of the knee: quantitative microscopic study of the patella and the femoral condyles. J Rheum 1987 (suppl 14); 14: 119-21.
4. Blanckaert A, Mazières B, Eeckhout Y, Vaes G. Direct extraction and assay of collagenase from human osteoarthritic articular cartilage. Clin Chim Acta 1989; 185: 73-80.
5. Mazières B, Berdah L. Effect of diacerheine (ART® 50) on an experimental post-contusive model of OA (abstract). Osteoarthritis Cartilage 1993; 1: 47.
6. Colombo C, Butler M, O'Burne E et al. A new model of osteoarthritis in rabbits: I. Development of knee joint pathology following lateral meniscectpmy and section of the fibular collateral and sesamoid ligaments. Arthritis Rheum 1983; 26: 875-86.