A quantitative study of regional cerebral blood flow in patients with dementia of Alzheimer type using single photon emission computed tomography - Clinical application of the IMP autoradiographic method (IMP ARG method)

Kakuigaku

Volumn 33, Issue 9, 1996, Pages 991-998

  Koshi, Yasuhiko ^a   Kitamura, Shin ^a   Komiyama, Tasuku ^a   Sakayori, Osamu ^a   Komaba, Yuichi ^a   Ohyama, Masashi ^a   Tsuganesawa, Toshikazu ^a   Mishina, Masahiro ^a   Ishiwata, Akiko ^a   Soya, Hiroyuki ^a   Nakazawa, Masaru ^a   Terashi, Akiro ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Dementia of Alzheimer type (DAT); Distribution volume (Vd); IMP autoradiographic method (IMP ARG method); Regional cerebral blood flow (rCBF); Single photon emission computed tomography (SPECT)

Indexed keywords

IOFETAMINE I 123;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; AUTORADIOGRAPHY; BRAIN BLOOD FLOW; BRAIN CORTEX; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; HUMAN; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

AGED; ALZHEIMER DISEASE; AMPHETAMINES; AUTORADIOGRAPHY; BRAIN; CEREBROVASCULAR CIRCULATION; FEMALE; HUMANS; IODINE RADIOISOTOPES; IOFETAMINE; MALE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0029801882     PISSN: 00227854     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. 123I]iodoamphetamine (IMP) tomography. J Nucl Med 23: 196-203, 1982
2. Murase K, Tanada S, Mogami H, Kawamura M, Miyagawa M, Yamada M, et al: Validity of microsphere model in cerebral blood flow measurement using N-isopropyl-p-(I-123)iodoamphetamine. Med Phys 17: 79-83, 1990
3. Yokoi T, Iida H, Itoh H, Kanno I: A new graphic plot analysis for cerebral blood flow and partition coefficient with iodine-123-iodoamphetamine and dynamic SPECT validation studies using oxygen-15-water and PET. J Nucl Med 34: 498-505, 1993
4. Iida H, Itoh H, Nakazawa M, Hatazawa J, Nishimura H, Onishi Y, et al: Quantitative mapping of regional cerebral blood flow using iodine-123-IMP and SPECT. J Nucl Med 35: 2019-2030, 1994
5. Reisberg B, Ferris SH, De Leon MJ: Senile dementia of the Alzheimer type: Diagnostic and differential diagnostic features with special reference to functional assessment staging. In Traber J, Gispen WH (eds.), Senile Dementia of the Alzheimer Type, Springer-Verlag, Berlin, 1985, pp. 18-37