Studies on new antitumor antibiotics, leptofuranins A, B, C and D. I. Taxonomy, fermentation, isolation and biological activities

Journal of Antibiotics

Volumn 49, Issue 10, 1996, Pages 974-979

  Hayakawa, Yoichi ^a   Sohda, Kin Ya ^a   Furihata, Keiko ^a   Kuzuyama, Tomohisa ^a   Shin ya, Kazuo ^a   Seto, Haruo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; LEPTOFURANIN DERIVATIVE; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENOVIRUS; ANIMAL CELL; ANTIBIOTIC BIOSYNTHESIS; APOPTOSIS; ARTICLE; CELL DEATH; CELL GROWTH; CELL STRUCTURE; CONTROLLED STUDY; CYTOSTASIS; DRUG CYTOTOXICITY; DRUG ISOLATION; FERMENTATION; GROWTH INHIBITION; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOMYCES; TAXONOMY; TUMOR CELL; VIRUS CELL TRANSFORMATION;

EID: 0029801620     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.49.974     Document Type: Article

References (15)

1. COBRINIK, D.; S. DOWDY, P. HINDS, S. MITTNACHT & R. WEINBERG: The retinoblastoma protein and the regulation of cell cycling. Trends Biochem. Sci. 17: 312-315, 1992
2. MORGENBESSER, S. D.; B. O. WILLIAMS, T. JACKS & R. A. DEPINHO: p53-dependent apoptosis produced by Rbdeficiency in the developing mouse lens. Nature 371: 72-74, 1994
3. DEBBAS, M. & E. WHITE: Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev. 7: 546-554, 1993
4. YEW, P. R. & A. J. BERK: Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein. Nature 357: 82-85, 1992
5. HAMAMOTO, T.; H. SETO & T. BEPPU: Leptomycins A and B, new antifungal antibiotics. II. Structure elucidation. J. Antibiotics 36: 646-650, 1983
6. HAYAKAWA, Y.; K. SOHDA & H. SETO: Studies on new antitumor antibiotics, leptofuranins A, B, C and D. II. Physicochemical properties and structure elucidation. J. Antibiotics 49: 980-984, 1996
7. CHEN, C. & H. OKAYAMA: High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell Biol. 7: 2745-2752, 1987
8. SHIRLING, E. B. & D. GOTTLIEB: Methods for characterization of Streptomyces species. Int. J. Syst. Bacteriol. 16: 313-340, 1966
9. NONOMURA, H.: Key for classification and identification of 458 species of the streptomyces included in ISP. J. Ferment. Technol. 52: 78-92, 1974
10. BECKER, B.; M. P. LECHEVALIER & H. A. LECHEVALIER: Chemical composition of cell wall preparations from strains of various genera of aerobic actinomycetes. Appl. Microbiol. 13: 236-243, 1965
11. SHIRLING, E. B. & D. GOTTLIEB: Cooperative description of type cultures of Streptomyces. II. Species descriptions from first study. Int. J. Syst. Bacteriol. 18: 69-189, 1968
12. SHIRLING, E. B. & D. GOTTLIEB: Cooperative description of type cultures of Streptomyces. III. Additional species descriptions from first and second studies. Int. J. Syst. Bacteriol. 18: 279-392, 1968
13. SHIRLING, E. B. & D. GOTTLIEB: Cooperative description of type cultures of Streptomyces. IV. Species descriptions from second, third and fourth studies. Int. J. Syst. Bacteriol. 19: 391-512, 1969
14. SHIRLING, E. B. & D. GOTTLIEB: Cooperative description of type cultures of Streptomyces. V. Additional species descriptions. Int. J. Syst. Bacteriol. 22: 265-394, 1972
15. WYLLIE, A. H.: Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556, 1980