Polymeric controlled-release amsacrine chemotherapy in an experimental glioma model

Acta Neurochirurgica

Volumn 138, Issue 11, 1996, Pages 1323-1330

  Wahlberg, L U ^a   Almqvist, P M ^a   Glantz, M J ^b   Boethius J ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b BROWN UNIVERSITY   (United States)

Author keywords

Amsacrine; Controlled drug delivery; Polymer implant; RG2 experimental glioma

Indexed keywords

AMSACRINE; IMMUNOSUPPRESSIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG RELEASE; EXPERIMENTAL NEOPLASM; GLIOMA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR CELL CULTURE;

EID: 0029801270     PISSN: 00016268     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01411063     Document Type: Article

References (32)

1. Barnard RO, Geddes JF (1987) The incidence of multifocal cerebral gliomus. A histologic study of large hemisphere sections. Cancer 60: 1519-1531
2. Bashir R, Hochberg F, Oot R (1988) Regrowth patterns of glioblastoma multiforme related to planning of interstitial brachytherapy radiation fields. Neurosurgery 23: 27-30
3. Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH (1994) Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci USA 91: 2076-2080
4. Bouvier G, Penn RD, Kroin JS, Beique R, Guerard MJ (1987) Direct delivery of medication into a brain tumor through multiple chronically implanted catheters. Neurosurgery 20: 286-291
5. Brem H, Mahaley M, Vick N, Black K, Schold S, Burger PC, Friedman A, Ciric I, Eller T, Cozzens J. et al (1991) Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas. J Neurosurg 74: 441-446
6. Brown LR, Wei CL, Langer R (1983) In vivo and in vitro release of macromolecules from polymeric drug delivery systems. J Pharm Sci 72: 1181-1185
7. Burger PC, Heinz ER, Shibata T, Kleihues P (1988) Topographic anatomy and CT correlations in the untreated glioblastoma multiforme. J Neurosurg 68: 698-704
8. Dakhil S, Ensminger W, Kindt G, Niederhuber J, Chandler W, Greenberg H, Wheeler R (1981) Implanted system for intraventricular drug infusion in central nervous system tumors. Cancer Treat Rep 65: 401-411
9. Earnest F, Kelly PJ, Scheithauer BW, Kall BA, Cascino TL, Ehman RL, Forbes GS, Axley PL (1988) Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy. Radiology 166: 823-827
10. Fine HA, Dear KB, Loeffler JS, Black PM, Canellos GP (1993) Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults [see comments]. Cancer 71: 2585-2597
11. Fojo AT, Ueda K, Slamon DJ, Poplack DG, Gottesman MN, Pastan I (1987) Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci USA 84: 265-269
12. Folkman J, Mark VH, Ervin F, Suematsu K, Hagiwara R (1968) Intracerebral gas anesthesia by diffusion through silicone rubber. Anesthesiology 29: 419-425
13. Harbaugh RE. Sauders RL, Reeder RF (1988) Use of implantable pumps for central nervous system drug infusions to treat neurological disease. Neurosurgery 23: 693-698
14. Hochberg FH, Pruitt A (1980) Assumptions in the radiotherapy of glioblastoma. Neurology 30: 907-911
15. Hoffman D, Wahlberg L, Aebischer P (1990) NGF Released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following fimbria-fornix lesion. Exp Neurol 110: 39-44
16. Hoshino T, Wilson CB, Rosenblum ML, Barker M (1975) Chemotherapeutic implications of growth fraction and cell cycle time in glioblastomas. J Neurosurg 43: 127-135
17. Judy KD, Olivi A, Buahin KG, Domb A, Epstein JI, Colvin OM, Brem H (1995) Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas. J Neurosurg 82: 481-486
18. Kelly PJ, Daumas DC, Scheithauer BW, Kall BA, Kispert DB (1987) Stereotactic histologic correlations of computed tomography- and magnetic resonance imaging-defined abnormalities in patients with glial neoplasms. Mayo Clin Proc 62: 450-459
19. Kestell P, Paxton JW, Evans PC, Young D, Jurlina JL, Robertson IG, Baguley BC (1990) Disposition of amsacrine and its analogue 9-([2-methoxy-4-[(methylsulfonyl)amino]phenyl]amino)-N,5-dimethyl-4- acridinecarboxamide (CI-921) in plasma, liver, and Lewis lung tumors in mice. Cancer Res 50: 503-508
20. Langer R, Brem H, Tapper D (1981) Biocompatibility of polymeric delivery systems for macromolecules. J Biomed Mater Res 15: 267-277
21. Liang BC, Thornton AFJ, Sandler HM, Greenberg HS (1991) Malignant astrocytomas: focal tumor recurrence after focal external beam radiation therapy. J Neurosurg 75: 559-663
22. Mughal TI, Glode LM, Braun TJ, Klingensmith W, Geier JM, Kindt GW (1986) Phase I clinical trial of intracarotid bis-chloroethylnitrosourea (BCNU) and 2́-dioxy-5-fluorouridine (FUDR) in malignant astrocytomas. J Neurooncol 3: 291-296
23. Nierenberg D, Harbaugh R, Maurer LH, Reeder T, Scott G, Fratkin J, Newman E (1991) Continuous intratumoral infusion of methotrexate for recurrent glioblastoma: a pilot study. Neurosurgery 28: 752-761
24. Penn RD, Kroin JS, Harris JE, Chiu KM, Braun DP (1983) Chronic intratumoral chemotherapy of a rat tumor with cisplatin and fluorouracil. Appl Neurophysiol 46: 240-244
25. Rhine WD, Hsieh DS, Langer R (1980) Polymers for sustained macromolecule release: procedures to fabricate reproducible delivery systems and control release kinetics. J Pharm Sci 69: 265-270
26. Rosenblum ML, Bowie DL, Walker MD (1973) Diffusion in vitro and in vivo of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea from silicone rubber capsules, a potentially new mode oof chemotherapy administration. Cancer Res 33: 906-914
27. Tamargo RJ, Epstein JI, Reinhard CS, Chasin M, Brem H (1989) Brain biocompatibility of a biodegradable, controlled-release polymer in rats. J Biomed Mater Res 23: 253-266
28. Ueno N, Refojo MF, Liu LH (1982) Controlled release rate of a lipophilic drug (BCNU) from a refillable silicone rubber device. J Biomed Mater Res 16: 669-677
29. Walter KA, Cahan MA, Gur A, Tyler B, Hilton J, Colvin OM, Burger PC, Domb A, Brem H (1994) Interstitial taxol delivered from a biodegradable polymer implant against experimental malignant glioma. Cancer Res 54: 2207-2212
30. Winn SR, Wahlberg L, Tresco PA, Aebischer P (1989) An encapsulated dopamine releasing polymer alleviates experimental parkinsonism in rats. Exp Neurol 105: 244-250
31. Yung WA, Horten BC, Shapiro WR (1980) Meningeal gliomatosis: a review of 12 cases. Ann Neurol 8: 605-608
32. Zwelling LA, Silberman L, Estey E (1986) Intercalator-induced. topoisomerase II-mediated DNA cleavage and its modification by antineoplastic antimetabolites. Int J Radiat Oncol Biol Phys 12: 1041-1047