Oral sensory stimulation improves glucose tolerance in humans: Effects on insulin, C-peptide, and glucagon

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 270, Issue 6 39-6, 1996, Pages

  Teff, Karen L ^a   Engelman, K ^b  

^a MONELL CHEMICAL SENSES CENTER   (United States)

^b NONE

Author keywords

cephalic responses; meal associated responses; metabolism; parasympathetic nervous system; sham feed; vagus

Indexed keywords

C PEPTIDE; GLUCAGON; GLUCOSE; INSULIN;

ADOLESCENT; ADULT; AREA UNDER THE CURVE; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; GLUCAGON BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INFUSION; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HUMAN; HUMAN EXPERIMENT; INSULIN BLOOD LEVEL; INTRAGASTRIC DRUG ADMINISTRATION; MALE; MOUTH CAVITY; NORMAL HUMAN; PRIORITY JOURNAL; SENSORY STIMULATION; VAGUS NERVE;

EID: 0029801084     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1996.270.6.r1371     Document Type: Article

References (37)

1. Adkins-Marshall, B., M. J. Pagliassotti, J. R. Ashe, C. C. Connolly, D. W. Neal, P. E. Williams, S. R. Myers, G. K. Hendrick, R. B. Adkins, and A. D. Cherrington. Role of hepatic nerves in response of liver to intraportal glucose delivery in dogs. Am. J. Physiol. 262 (Endocrinol. Metab. 25): E679-E686, 1992.
2. Anderson, H. B., E. Christiansen, A. Volund, S. Madsbad, K. Rasmussen, F. Burcharth, and N. J. Christensen. Sham feeding increases glucose tolerance by a mechanism independent of insulin secretion. Digestion 56: 253-258, 1995.
3. Bellisle, F., J. Louis-Sylvestre, F. Demozay, D. Blazy, and J. Le Magnen. Reflex insulin response associated to food intake in human subjects. Physiol. Behav. 31: 515-521, 1983.
4. Bloom, S. R., N. J. A. Vaughan, and R. C. G. Russell. Vagal control of glucagon release in man. Lancet 2: 546-549, 1974.
5. Boyle, P. J., S. B. Liggett, S. D. Shah, and P. E. Cryer. Direct muscarinic cholinergic inhibition of hepatic glucose production in humans. J. Clin. Invest. 82: 445-449, 1988.
6. Bruce, D. G., D. J. Chisholm, L. H. Storlein, and E. W. Kraegen. Physiological importance of deficiency in early prandial insulin secretion in non-insulin dependent diabetics. Diabetes 37: 736-744, 1988.
7. Calles-Escandon, J., and D. C. Robbins. Loss of early phase of insulin release in humans impairs glucose tolerance and blunts thermic effect of glucose. Diabetes 36: 1167-1172, 1987.
8. Campfield, L. A., and F. Smith. Neural control of insulin secretion: interaction of norepinephrine and acetyleholine. Am. J. Physiol. 244 (Regulatory Integrating Comp. Physiol. 13): R629-R634, 1983.
9. Chap, Z., T. Ishida, J. Chou, R. Lewis, C. Hartley, M. Entman, and J. B. Field. Effects of atropine and gastric inhibitory polypeptide on hepatic glucose uptake and the insulin concentration. J. Clin. Invest. 76: 1174-1181, 1985.
10. D'Alessio, D. A., S. E. Kahn, C. R. Leusner, and J. W. Ensinck. Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-dependent glucose disposal. J. Clin. Invest. 93: 2263-2266, 1994.
11. De Jong, A., J. H. Strubbe, and A. B. Steffens. Hypothalamic influence on insulin and glucagon release in the rat. Am. J. Physiol. 233 (Endocrinol. Metab. Gastrointest. Physiol. 2): E380-E388, 1977.
12. Diamond, P., L. Brondel, and J. LeBlanc. Palatability and postprandial thermogenesis in dogs. Am. J. Physiol. 248 (Endocrinol. Metab. 11): E75-E79, 1985.
13. Eaton, R. P., R. C. Allen, D. S. Schade, K. M. Erickson, and J. Standefer. Prehepatic insulin production in man: kinetic analysis using peripheral connecting peptide. J. Clin. Endocrinol. Metab. 51: 520-528, 1980.
14. Elrick, H., L. Stimmler, C. J. Hlad, and Y. Arai. Plasma insulin response to oral and intravenous glucose administration. J. Clin. Endocrinol. Metab. 24: 1076-1082, 1964.
15. Feldman, M., and C. T. Richardson. Role of thought, smell, and taste of food in the cephalic phase of gastric acid secretion in humans. Gastroenterology 90: 428-433, 1986.
16. Havel, P. J., and G. J. Taborsky. The contribution of the autonomic nervous system to increased glucagon secretion during hypoglycemic stress: update 1994. Endocrin. Rev. 2: 201-204, 1994.
17. Kraegen, E. W., D. J. Chisholm, and M. E. McNamara. Timing of insulin delivery with meals. Horm. Metab. Res. 13: 365-367, 1981.
18. LeBlanc, J., and L. Brondel. Role of palatability on meal-induced thermogenesis in human subjects. Am. J. Physiol. 248 (Endocrinol. Metab. 11): E333-E335, 1985.
19. LeBlanc, J., and M. Cabanac. Cephalic postprandial thermogenesis in human subjects. Physiol. Behav. 46: 479-482, 1989.
20. Lorentzen, M., S. Madsbad, H. Kehlet, and B. Tronier. Effect of sham-feeding on glucose tolerance and insulin secretion. Acta Endocrinol. 115: 84-86, 1987.
21. Louis-Sylvestre, J. Preabsorptive insulin release and hypoglycemia in rats. Am. J. Physiol. 230: 56-60, 1976.
22. McGuire, E. A. H., J. H. Helderman, J. D. Tobin, R. Andres, and N. Berman. Effects of arterial versus venous sampling on analysis of glucose kinetics in man. J. Appl. Physiol. 41: 565-573, 1976.
23. Miyoshi, H., G. I. Shulman, E. J. Peters, M. H. Wolfe, D. Elahi, and R. R. Wolfe. Hormonal control of substrate cycling in humans. J. Clin. Invest. 81: 1545-1555, 1988.
24. Myers, S. R., O. P. MeGuiness, D. W. Neal, and A. D. Cherrington. Intraportal glucose delivery alters the relationship between net hepatic glucose uptake and the insulin concentration. J. Clin. Invest. 87: 930-939, 1991.
25. Nicolaidis, S. Early systemic responses to orogastric stimulation in the regulation of food and water balance: functional and electrophysiological data. Ann. NY Acad. Sci. 157: 1176-1203, 1969.
26. O'Hara, I., S. Otsuka, and Y. Yugari. Cephalic phase response of pancreatic exocrine secretion in conscious dogs. Am. J. Physiol. 254 (Gastrointest. Liver Physiol. 17): G424-G428, 1988.
27. Pavlov, I. The Work of the Digestive Glands. London, UK: Charles Griffin, 1902, p. 76-92.
28. Perley, M., and D. M. Kipnis. Plasma insulin responses to oral and intravenous glucose administration. J. Clin. Endocrinol. 24: 1076-1082, 1965.
29. Powley, T. L. The ventromedial hypothalamic syndrome, satiety and a cephalic phase hypothesis. Psychol. Rev. 84: 89-126, 1977.
30. Proietto, J., F. Rohner-Jeanrenaud, E. Ionescu, and B. Jeanrenaud. Role for the oropharynx in regulation of glycemia. Diabetes 36: 791-795, 1987.
31. Shulman, G. I., and B. R. Landau. Pathways of glycogen repletion. Physiol. Rev. 72: 1019-1033, 1992.
32. Steffens, A. B. Influence of the oral cavity on insulin release in the rat. Am. J. Physiol. 230: 1411-1415, 1976.
33. Strubbe, J. H., and A. B. Steffens. Rapid insulin release after ingestion of a meal in the unanesthetized rat. Am. J. Physiol. 229: 1019-1022, 1975.
34. Teff, K. L., B. Levin, and K. Engelman. Oral sensory stimulation in men: effects on insulin, C-peptide, and catecholamines. Am. J. Physiol. 265 (Regulatory Integrative Comp. Physiol. 34): R1223-R1230, 1993.
35. Teff, K. L., R. D. Mattes, and K. Engelman. Cephalic phase insulin release in normal weight males: verification and reliability. Am. J. Physiol. 261 (Endocrinol. Metab. 24): E430-E436, 1991.
36. Teff, K. L., R. D. Mattes, K. Engelman, and J. Mattern. Cephalic-phase insulin release in obese and normal-weight men: relation to postprandial insulin. Metabolism 42: 1600-1608, 1993.
37. Zawalich, W. S., K. C. Zawalich, and H. Rasmussen. Cholinergic agonists prime the B-cell to glucose stimulation. Endocrinology 125: 2400-2406, 1986.