Studies on pyrazinoylguanidine: 4. Upregulation of phosphodiesterase activity in rat adipose tissue and downregulation of gluconeogenesis and adenosine 3′,5′-monophosphate concentrations in perfused rat liver

Pharmacology

Volumn 53, Issue 4, 1996, Pages 211-218

  A Rahim, Yousif I ^a   Rannels, Sharon L ^a   Kimball, Scot R ^a   Beyer, Karl H ^a   Vesell, Elliot S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Cyclic AMP; Diabetes mellitus; Gluconeogenesis; Phosphodiesterase; Pyrazinoylguanidine

Indexed keywords

ANTIDIABETIC AGENT; CYCLIC AMP; GUANIDINE DERIVATIVE; INSULIN; PHOSPHODIESTERASE; PYRAZINOYLGUANIDINE; THEOPHYLLINE; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; GLUCONEOGENESIS; LIPOLYSIS; LIVER PERFUSION; MALE; NONHUMAN; NUCLEIC ACID METABOLISM; PRIORITY JOURNAL; RAT;

ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; CELL MEMBRANE; CYCLIC AMP; DOWN-REGULATION; GLUCONEOGENESIS; GUANIDINES; HYPOGLYCEMIC AGENTS; LIVER; MALE; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PYRAZINES; RATS; RATS, SPRAGUE-DAWLEY; THEOPHYLLINE; UP-REGULATION;

EID: 0029800891     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000139432     Document Type: Article

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