Active vs. passive resistance, dose-response relationships, high dose chemotherapy, and resistance modulation: A hypothesis

Investigational New Drugs

Volumn 14, Issue 2, 1996, Pages 115-130

  Stewart, David J ^a   Raaphorst, G Peter ^a   Yau, Jonathan ^a   Beaubien, Arthur R ^b  

^a OTTAWA REGIONAL CANCER CENTRE   (Canada)

^b HEALTH CANADA   (Canada)

Author keywords

Active; Competitive; Dose response curve; Noncompetitive; Passive; Resistance

Indexed keywords

ANTINEOPLASTIC AGENT; GLUTATHIONE; GLYCOPROTEIN P;

ANIMAL CELL; APOPTOSIS; BINDING AFFINITY; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CELL KILLING; COMPETITIVE INHIBITION; DOSE RESPONSE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG POTENTIATION; DRUG RESISTANCE; DRUG UPTAKE; GENE AMPLIFICATION; GENE DELETION; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; REGRESSION ANALYSIS; REVIEW; TUMOR GROWTH;

EID: 0029800622     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00210782     Document Type: Review

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