The clinical use of 99m-Tc-labeled WBC scintigraphy in critically ill surgical and trauma patients with occult sepsis

Intensive Care Medicine

Volumn 22, Issue 9, 1996, Pages 867-871

  Minoja, G ^a   Chiaranda, M ^a   Fachinetti, A ^b   Raso, M ^a   Dominioni, L ^a   Torre, D ^b   De Palma, D ^b  

^a UNIVERSITY OF PAVIA   (Italy)

^b Ospedale Multizonale Varese   (Italy)

Author keywords

99m Tc HMPAO labeled WBCs; Infection; Intensive care medicine; Occult sepsis; Scintigraphy; Trauma

Indexed keywords

TECHNETIUM 99M;

ARTICLE; CLINICAL STUDY; COMPUTER ASSISTED TOMOGRAPHY; CRITICAL ILLNESS; HUMAN; HUMAN CELL; INTENSIVE CARE; ISOTOPE LABELING; LEUKOCYTE; SCINTIGRAPHY; SEPSIS; SURGICAL PATIENT; ULTRASOUND; UNIVERSITY HOSPITAL;

EID: 0029800375     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02044109     Document Type: Article

References (25)

1. Nathens AB, Chu PT, Marshall JC (1992) Nosocomial infection in the surgical intensive care unit. Infect Dis Clin North Am 6:657-675
2. Froelich JW, Swanson D (1984) Imaging of inflammatory processes with labeled cells. Semin Nucl Med 14: 128-140
3. Gerzof SH, Oates ME (1988) Imaging techniques for infections in the surgical patient. Surg Clin North Am 68: 147-165
4. Peters AM, Osman S, Henderson BL, Kelly JD, Danpure HJ, Hawker RJ, Hodgson SJ, Neirinckx RD, Lavender JP (1986) Clinical experience with 99m-Tc HMPAO for labeling leucocytes and imaging inflammation. Lancet II: 946-949
5. Becker W, Schomann E, Fischbach W, Borner W, Gruner KR (1988) Comparison of 99m-Tc HMPAO and 111-In-oxine labeled granulocytes in man: first clinical results. Nucl Med Commun 9: 435-447
6. Vorne M, Soini I, Lantto T, Paakkinen S (1989) Technetium-99m HMPAO-labeled leukocytes in detection of inflammatory lesions: comparison with gallium-67 citrate. J Nucl Med 30: 1332-1336
7. Datz FL (1993) The current status of radionuclide infection imaging. Nucl Med Annu 47-76
8. Kao CH, Wang JL, Liao SQ, Wang SJ (1992) Tc-99m HMPAO labeled WBCs in the detection of occult sepsis in the intensive care unit. Intensive Care Med 18:15-19
9. Rello J, Ricart M, Mirelis B, Quintana E, Gurgui M, Net A, Prats G (1994) Nosocomial bacteremia in a medical-surgical intensive care unit: epidemiologic characteristics and factors influencing mortality in 111 episodes. Intensive Care Med 20:94-98
10. European Society of Intensive Care Medicine (1994) The problem of sepsis. An expert report. Intensive Care Med 20:300-304
11. Brown RB, Hosmer D, Chen HC, Teres D, Sands M, Bradley S, Opiz E, Szwedzinski D, Opalenik D (1985) A comparison of infections in different ICUs within the same hospital. Crit Care Med 13:472-480
12. Emmerson AM (1990) The epidemiology of infections in intensive care units. Intensive Care Med 16 [Suppl 3] 16:S197-S200
13. Thomas R, Le Tulzo Y (1993) Clinical and etiological diagnosis of septic states. Rev Prat 43:35-40
14. European Prevalence of Infection in Intensive Care (EPIC study) (1993). In: Suter P, Vincent JL (eds) Milestones in hospital infections. Medical Action Communications, Thorpe, Egham Surrey, UK, pp 63-64
15. Borman KR, Brown PM, Mezera KK, Jhaveri H (1992) Occult fever in surgical ICU patients is seldon caused by sinusitis. Am J Surg 164:412-416
16. Holzapfel L, Chvevret S, Madinier G, Ohen F, Demingeon G, Coupry A, Chaudet M (1993) Influence of long-term oro- or nasotracheal intubation on nosocomial maxillary sinusitis and pneumonia: results of a prospective, randomized, clinical trial. Crit Care Med 21:1132-1138
17. Flancbaum L, Wilson GA, Choban PS (1993) The significance of a positive test of morphine cholescintigraphy in hospitalized patients. J Am Coll Surg 177:227-230
18. Ho HS, Wisner DH (1993) Splenic abscess in intensive care unit. Arch Surg 128:842-846
19. Meakins JL (1991) Diagnosis and mechanisms of occult sepsis. In: Taylor RW, Shoemaker WC (eds) Critical care: state of the art, vol XII. Society of Critical Care Medicine, Fullerton, pp 141-156
20. Speck EL (1986) Fever and fever of unknown etiology. In: Reese RE, Douglas RG (eds) A practical approach to infectious diseases, 2nd edn. Little, Brown, Boston, pp 1-17
21. Meduri GU, Belenchia JM, Estes RJ, Wunderink RG, Torky EM, Leeper KV (1991) Fibroproliferative phase of ARDS. Clinical findings and effects of corticosteroids. Chest 100:943-952
22. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference (1992) Definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20: 864-874
23. Datz FL, Anderson CE, Ahluwalia R, Whiting JH, Gabor FV, Morton KA, Christian PE, Crebs K, Neptune M, Rauh DA (1994) The efficacy of indium-111-polyclonal IgG for the detection of infection and inflammation. J Nucl Med 35:74-83
24. Datz FL, Thorne DA (1986) Effect of antibiotic therapy on sensitivity of 111-In-labeled leukocyte scans. J Nucl Med 27:1849-1853
25. Fry DE (1994) Noninvasive imaging tests in the diagnosis and treatment of intra-abdominal abscesses in the post-operative patient. Surg Clin North Am 74:693-709