Effects of short-term recombinant human insulin-like growth factor I administration on bone turnover in osteopenic women with anorexia nervosa

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 11, 1996, Pages 3864-3870

  Grinspoon, Steven ^a   Baum, Howard ^a   Lee, Kristen ^a   Anderson, Ellen ^a   Herzog, David ^a   Klibanski, Anne ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT SOMATOMEDIN C;

ADULT; ANOREXIA NERVOSA; ARTICLE; BONE ATROPHY; BONE DENSITY; BONE MASS; BONE TURNOVER; CLINICAL ARTICLE; DOSE RESPONSE; FEMALE; HUMAN; OSSIFICATION; OSTEOLYSIS; OSTEOPENIA; OSTEOPOROSIS; PRIORITY JOURNAL;

ADOLESCENT; ADULT; ANOREXIA NERVOSA; BIOLOGICAL MARKERS; BONE DENSITY; BONE DISEASES, METABOLIC; BONE REMODELING; BONE RESORPTION; FEMALE; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; OSTEOCALCIN; OSTEOGENESIS; RECOMBINANT PROTEINS;

STAPHYLOCOCCUS PHAGE 187;

EID: 0029799208     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.11.3864     Document Type: Article

References (48)

1. Lucas AR, Beard CM, O'Fallon WM, Kurland LT. 1991 50-year trends in the incidence of anorexia nervosa in Rochester, MN: a population-based study. Am J Psychiatry. 148:917-922.
2. Biller BMK, Saxe V, Herzog DB, Rosenthal DI, Holzman S, Klibanski A. 1989 Mechanisms of osteoporosis in adult and adolescent women with anorexia nervosa. J Clin Endocrinol Metab. 68:548-554.
3. Bachrach LK, Guido D, Katzman D, Litt IF, Marcus R. 1990 Decreased bone density in adolescent girls with anorexia nervosa. Pediatrics. 86:440-447.
4. Bachrach L, Katzman D, Litt I, Guido D, Marcus R. 1991 Recovery from osteopenia in adolescent girls with anorexia nervosa. J Clin Endocrinol Metab. 72:602-606.
5. Rigotti NA, Neer RM, Skates SJ, Herzog DB, Nussbaum SR. 1991 The clinical course of osteoporosis in anorexia nervosa. JAMA. 265:1133-1138.
6. Klibanski A, Biller BMK, Schoenfeld DA, Herzog DB, Saxe VC. 1995 The effects of estrogen administration on trabecular bone loss in young women with anorexia nervosa. J Clin Endocrinol Metabolism. 80:898-904.
7. Bennet A, Chen T, Feldman D, Hintz RL, Rosenfeld RG. 1984 Characterization of insulin-like growth factor I receptors on cultured rat bone cells: regulation of receptor concentration by glucocorticoids. Endocrinology. 115:1577-1583.
8. Canalis E. 1980 Effect of insulinlike growth factor I on DNA and protein synthesis in cultured rat calvaria. J Clin Invest. 66:709-719.
9. Hock JM, Centrella M, Canalis E. 1988 Insulin-like growth factor I has independent effects on bone matrix formation and cell replication. Endocrinology. 122:254-260.
10. Isaksson OGP, Lindahl A, Nilsson A, Isgaard J. 1987 Mechanisms of the stimulatory effect of growth hormone on longitudinal bone growth. Endocr Rev. 8:426-438.
11. McCarthy TL, Centrella M, Canalis E. 1989 Regulatory effects of insulin-like growth factors-I and II on bone collagen synthesis in rat calvarial cultures. Endocrinology. 124:301-309.
12. Counts DR, Gwirtsman H, Carlsson LMS, Lesem M, Cutler GB. 1992 The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins. J Clin Endocrinol Metab. 75:762-767.
13. Grinspoon SK, Baum HBA, Peterson S, Klibanski A. 1995 Effects of rhIGF-I administration on bone turnover during short-term fasting. J Clin Invest. 96:900-906.
14. Grinspoon S, Baum H, Kim V, Coggins C, Klibanski A. 1995 Decreased bone formation and increased mineral dissolution during acute fasting in young women. J Clin Endocrinol Metab. 80:3628-3633.
15. Garnero P, Shih WJ, Gineyts E, Karpf DB, Delmas PD. 1994 Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment. J Clin Endocrinol Metab. 79:1693-1700.
16. Prestwood KM, Pilbeam CC, Burleson JA, et al. 1994 The short term effects of conjugated estrogen on bone turnover in older women. J Clin Endocrinol Metab. 79:366-371.
17. Turner RT, Riggs BL, Spelsberg TC. 1994 Skeletal effects of estrogen. Endocr Rev. 15:275-300.
18. Uebelhart D, Schlemmer A, Johansen JS, Gineyts E, Christiansen C, Delmas PD. 1991 Effect of menopause and hormone replacement therapy on the urinary excretion of pyridinium cross-links. J Clin Endocrinol Metab 72:367-373.
19. First M. 1994 Diagnostic and statistical manual of mental disorders, 4th ed. Washington DC: 539-545.
20. Durnin JVGA, Womersley J. 1974 Body fat assessed from total body density and its estimation from skinfold thickness. Br J Nutr. 32:77-97.
21. Metropolitan Life Insurance Co. 1983 Metropolitan Height and Weight Tables. Stat Bull. 64:2-9.
22. Segal KR, Van Loan M, Fitzgerald PI, Hodgeson JA, Van Itallie TB. 1988 Lean body mass estimation by bioelectrical impedance analysis: a four site cross validation study. Am J Clin Nutr. 47:7-14.
23. Case Records of the Massachusetts General Hospital. 1992 Weekly clinicopathological exercises. Normal reference laboratory values [see comments]. N Engl J Med. 327:718-724.
24. Uebelhart D, Gineyts E, Chapuy MC, Delmas PD. 1990 Urinary excretion of pyridinium crosslinks: a new marker of bone resorption in metabolic bone disease. Bone Mineral. 8:87-96.
25. Finkelstein J, Cleary R, Butler J, et al. 1994 A comparison of lateral versus anterior-posterior spine dual energy x-ray absorptiometry for the diagnosis of osteopenia. J Clin Endocrinol Metab. 78:724-730.
26. Favus M. 1993 Primer on the metabolic bone diseases and disorders of metabolism. New York: Raven Press: 426-430.
27. Biller BMK, Coughlin JF, Saxe V, Schoenfeld D, Spratt DI, Klibanski A. 1991 Osteopenia in women with hypothalamic amenorrhea. Obstet Gynecol. 78:996-1001.
28. Klibanski A, Biller BMK, Rosenthal DI, Schoenfeld DA, Saxe V. 1988 Effects of prolactin and estrogen deficiency in amenorrheic bone loss. J Clin Endocrinol Metab. 67:124-130.
29. Fonseca VA, D'Souza V, Houlder S, Thomas M, Wakeling A, Dandona P. 1988 Vitamin D deficiency and low osteocalcin levels in anorexia nervosa. J Clin Pathol. 41:195-197.
30. LeRoith D, Clemmons D, Nissley P, Rechter MM. 1992 NIH conference. Insulin-like growth factors in health and disease [see comments]. Ann Intern Med. 116:854-862.
31. Isley WL, Underwood LE, Clemmons DR. 1983 Dietary components that regulate serum somatomedin-C concentrations in humans. J Clin Invest. 71:175-182.
32. Isley WL, Underwood LE, Clemmons DR. 1984 Changes in plasma somatomedin-C in response to ingestion of diets with variable protein and energy content. J Parenter Enteral Nutr. 8:407-411.
33. Thissen J, Ketelslegers J, Underwood L. 1994 Nutritional regulation of the insulin-like growth factors. Endocr Rev. 15:80-101.
34. Clemmons DR, Klibanski A, Underwood LE, et al. 1981 Reduction of plasma immunoreactive somatomedin C during fasting in humans. J Clin Endocrinol Metab. 53:1247-1250.
35. Schlecter N, Russell S, Spencer E, Nicoll C. 1986 Evidence suggesting that the direct growth promoting effects of growth hormone on cartilage in vivo is mediated by the local production of somatomedin. Proc Natl Acad Sci USA. 83:7932-7933.
36. Laron Z, Klinger B, Jensen LT, Erster B. 1991 Biochemical and hormonal changes induced by one week of administration of rIGF-I to patients with Laron type dwarfism. Clin Endocrinol (Oxf). 35:145-150.
37. Sartorio A, Conti A, Monzani M, Morabito F, Faglia G. 1993 Growth hormone treatment in adults with GH deficiency: effects on new biochemical markers of bone and collagen turnover. J Endocrinol Invest. 16:893-898.
38. Ernst M, Rodan G. 1990 Increased activity of insulin-like growth factor (IGF) in osteoblastic cells in the presence of growth hormone (GH): positive correlation with the presence of the GH-Induced IGF-binding protein BP-3. Endocrinology. 127:807-814.
39. Ernst M, Rodan GA. 1991 Estradiol regulation of insulin-like growth factor-I expression in osteoblastic cells: evidence for transcriptional control. Mol Endocrinol. 5:1081-1089.
40. Canalis E, Centrella M, Burch W, McCarthy TL. 1989 Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures. J Clin Invest. 83:60-65.
41. Ghiron LJ, Thompson JL, Holloway L, et al. 1995 Effects of recombinant insulin-like growth factor-I and growth hormone on bone turnover in elderly women. J Bone Min Res. 10:1844-1852.
42. Johansson AG, Lindh E, Blum WF, Kollerup G, Sorenson OH, Livinghall S. 1996 Effects of growth hormone and insulin-like growth factor I in men with idiopathic osteoporosis. J Clin Endocrinol Metab. 81:44-48.
43. Johansson AG, Lindh E, Kollerup G, Livinghall S. 1995 Dose-dependent effects of IGF-I on the metabolism of collagen-type I in male osteoporosis [Abstract]. J Bone Min Res. 10 (Suppl 1):S249.
44. Hill PA, Reynolds JJ, Meikle MC. 1995 Osteoblasts mediate insulin-like growth factor-I and II stimulation of osteoclast formation and function. Endocrinology. 136:124-131.
45. Pottraz ST, Bellido T, Mocharia H, Crabb D, Manolagas SC. 1994 17β-Estradiol inhibits expression of human interleukin-6 promoter-reporter constructs by a receptor-dependent mechanism. J Clin Invest. 93:944-950.
46. Slootweg MC, Most WW, van Beek E, Schot LPC, Papapoulos SE, Lowik CWGM. 1992 Osteoclast formation together with interleukin-6 production in mouse long bones is increased by insulin-like growth factor-I. J Endocrinol. 132:433-438.
47. Delmas PD. 1993 Biochemical markers of bone turnover. I. Theoretical considerations and clinical use in osteoporosis. Am J Med. 95:11S-16S.
48. Ebeling PR, Jones JD, O'Fallon WM, Janes CH, Riggs BL. 1993 Short-term effects of recombinant human insulin-like growth factor-I on bone turnover in normal women. J Clin Endocrinol Metab. 77:1384-1387.