Intracellular metabolism of Ara-C and resulting DNA fragmentation and apoptosis of human AML HL-60 cells possessing disparate levels of Bcl-2 protein

Leukemia

Volumn 10, Issue 11, 1996, Pages 1731-1740

  Bullock, G ^a   Ray, S ^b   Reed, J C ^c   Krajewski, S ^c   Ibrado, A M ^b   Huang, Y ^b   Bhalla, K ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c BURNHAM INSTITUTE   (United States)

Author keywords

Ara CTP; Bax; Bcl 2; Bcl x(L)

Indexed keywords

CELL PROTEIN; CYTARABINE; DNA FRAGMENT; ONCOPROTEIN; PROTEIN BCL 2;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; ARTICLE; CELL DEATH; CELL METABOLISM; CELL STRAIN HL 60; CELL STRUCTURE; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; DNA SYNTHESIS; DNA SYNTHESIS INHIBITION; DNA TRANSFECTION; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG METABOLISM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0029799110     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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