Herpesvirus vector-mediated gene delivery to human monocytes

Human Gene Therapy

Volumn 7, Issue 11, 1996, Pages 1331-1338

  Weir, Jerry P ^a   Dacquel, Emelyn J ^b   Aronovitz, Jason ^b  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON;

ARTICLE; EXPRESSION VECTOR; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; HERPES VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; MONOCYTE; MONOLAYER CULTURE; VIRUS INHIBITION; VIRUS REPLICATION;

EID: 0029798787     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1996.7.11-1331     Document Type: Article

References (37)

1. ABOULKER, J.-P., and SWART, A.M. (1993). Preliminary analysis of the Concorde trial. Lancet 341, 889-890.
2. ANDERSON, J.K., GARBER, D.A., MEANEY, C.A., and BREAKEFIELD, X.O. (1992). Gene transfer into mammalian central nervous system using herpes virus vectors: Extended expression of bacterial lacZ in neurons using the neuron-specific enolase promoter. Hum. Gene Ther. 3, 487-499.
3. CHATTERJEE, S., JOHNSON, P.R., and WONG, K.K. (1992). Dual-target inhibition of HIV-1 in vitro by means of an adeno-associated virus antisense vector. Science 258, 1485-1488.
4. CHIOCCA, E.A., CHOI, B.B., CAI, W., DELUCA, N.A., SCHAFFER, P.A., DIFIGLIA, M., BREAKEFIELD, X.O., and MARTUZA, R.L. (1990). Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants. New Biol. 2, 739-746.
5. COEN, D.M., KOSZ-VNENCHAK, M., JACOBSON, J.G., LEIB, D.A., BOGARD, C.L., SCHAFFER, P.A., TYLER, K.L., and KNIPE, D.M. (1989). Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate. Proc. Natl. Acad. Sci. USA 86, 4736-4740.
6. COLIGAN, J.E., KRUISBEEK, A.M., MARGULIES, D.H., SHEVACH, E.M., and STROBER, W., eds. (1991). Current Protocols in Immunology. (Wiley, New York).
7. CULVER, K., CORNETTA, K., MORGAN, R., MORECKI, S., AEBERSOLD, P., KASID, A., LOTZE, M., ROSENBERG, S.A., ANDERSON, W.F., and BLAESE, R.M. (1991). Lymphocytes as cellular vehicles for gene therapy in mouse and man. Proc. Natl. Acad. Sci. USA 88, 3155-3159.
8. DELUCA, N.A., and SCHAFFER, P.A. (1987). Activities of herpes simplex type 1 (HSV-1) ICP4 genes specifying nonsense peptides. Nucleic Acids Res. 15, 4491-4511.
9. DELUCA, N.A., McCARTHY, A.M., and SCHAFFER, P.A. (1985). Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J. Virol. 56, 558-570.
10. DI MARZO VERONESE, F., SARNGADHARAN, M.G., RAHMAN, R., MARKHAM, P.D., POPOVIC, M., BODNER, A.J., and GALLO, R.C. (1985). Monoclonal antibodies specific for p24, the major core protein of human T-cell leukemia virus type III. Proc. Natl. Acad. Sci. USA 82, 5199-5202.
11. FAUCI, A.S. (1988). The human immunodeficiency virus: Infectivity and mechanisms of pathogenesis. Science 239, 617622.
12. FAUCI, A.S. (1993). Multifactorial nature of human immunodeficiency virus disease: implications for therapy. Science 262, 1011-1018.
13. FINK, J.K., CORRELL, P.H., PERRY, L.K., BRADY, R.O., and KARLSSON, S. (1990). Correction of glucocerebrosidase after retroviral-mediated gene transfer into hematopoietic progenitor cells from patients with Gaucher disease. Proc. Natl. Acad. Sci. USA 87, 2334-2338.
14. FISCHL, M.A., RICHMAN, D.D., HANSEN, N., COLLIER, A.C., CAREY, J.T., PARA, M.F., HARDY, W.D., DOLIN, R., POWDERLY, W.G., ALLAN, J.D., WONG, B., MERIGAN, T.C., MCAULIFFE, V.J., HYSLOP, N.E., RHAME, F.S., BALFOUR, JR., H.H., SPECTOR, S.A., VOLBERDING, P., PETTINELLI, C., ANDERSON, J., and AIDS CLINICAL TRIALS GROUP. (1990). The safety and efficacy of zidovudine (AZT) in the treatment of subjects with mildly symptomatic human immunodeficiency virus type 1 (HIV) infection. Ann. Intern. Med. 112, 727-737.
15. GENDELMAN, H.E., ORENSTEIN, J.M., MARTIN, M.A., FERRUA, C., MITRA, R.T., PHIPPS, T., WAHL, L.A., LANE, H.C., FAUCI, A.S., BURKE, D.S., SKILLMAN, D., and MELTZER, M.S. (1988). Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes. J. Exp. Med. 167, 1428-1441.
16. JOHNSON, P.A., MIYANOHARA, A., LEVINE, F., CAHILL, T., and FRIEDMANN, T. (1992). Cytotoxicity of a replication-defective mutant of herpes simplex virus type 1. J. Virol. 66, 2952-2965.
17. JOHNSON, P.A., WANG, M.J., and FRIEDMANN, T. (1994). Improved cell survival by the reduction of immediate-early gene expression in replication-defective mutants of herpes simplex virus type 1 but not by mutation of the virion host shutoff function. J. Virol. 68, 6347-6362.
18. LANE, H.C., DAVEY, V., KOVACS, J.A., FEINBERG, J., METCALF, J.A., HERPIN, J, B., WALKER, R., DEYTON, L., DAVEY, JR., R.T., FALLOON, J., POLIS, M.A., SALZMAN, N.P., BASELER, M., MASUR, H., and FAUCI, A.S. (1990). Interferon-alpha in patients with asymptomatic human immunodeficiency virus (HIV) infection. Ann. Intern. Med. 112, 805-811.
19. LEIB, D.A., COEN, D.M., BOGARD, C.L., HICKS, K.A., YAGER, D.R., KNIPE, D.M., TYLER, K.L., and SCHAFFER, P.A. (1989). Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. J. Virol. 63, 759-768.
20. LOKENSGARD, J.R., BLOOM, D.C., and FELDMAN, L.T. (1994). Long-term promoter activity during herpes simplex virus latency. J. Virol. 68, 7148-7158.
21. MARGOLIS, T.P., BLOOM, D.C., DOBSON, A.T., FELDMAN, L.T., and STEVENS, J.G. (1993). Decreased reporter gene expression during latent infection with HSV LAT promoter constructs. Virology 197, 585-592.
22. McCARTHY, A.M., MCMAHAN, L., and SCHAFFER, P.A. (1989). Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient. J. Virol. 63, 18-27.
23. MELTZER, M.S., SKILLMAN, D.R., GOMATOS, P.J., KALTER, D.C., and GENDELMAN, H.E. (1990). Role of mononuclear phagocytes in the pathogenesis of human immunodeficiency virus infection. Annu. Rev. Immunol. 8, 169-194.
24. MIYANOHARA, A., JOHNSON, P.A., ELAM, R.L., DAI, Y., WITZTUM, J.L., VERMA, I.M., and FRIEDMANN, T. (1992). Direct gene transfer to the liver with herpes simplex virus type 1 vectors: Transient production of physiologically relevant levels of circulating factor IX. New Biol. 4, 238-246.
25. NOLTA, J.A., YU, X.J., BAHNER, I., and KOHN, D.B. (1992). Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow. J. Clin. Invest. 90, 342-348.
26. OHASHI, T., BOGGS, S., ROBBINS, P., BAHNSON, A., PATRENE, K., WEI, F.-S., WEI, J.-F., LI, J., LUCHT, L., FEI, Y., CLARK, S., KIMAK, M., HE, H., MOWERY-RUSHTON, P., and BARRANGER, J.A. (1992). Efficient transfer and sustained high expression of the human glucocerebrosidase gene in mice and their functional macrophages following transplantation of bone marrow transduced by a retroviral vector. Proc. Natl. Acad. Sci. USA 89, 11332-11336.
27. PRICE, R.W., BREW, B., SIDTIS, J., ROSENBLUM, M., SCHECK, A.C., and CLEARY, P. (1988). The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex. Science 239, 586-592.
28. RICH, E.A., CHEN, I.S.Y., ZACK, J.A., LEONARD, M.L., and O'BRIEN, W.A. (1992). Increased susceptibility of differentiated mononuclear phagocytes to productive infection with human immunodeficiency virus-1 (HIV-1). J. Clin. Invest. 89, 176-183.
29. RICHES, D.W.H., and HENSON, P.M. (1986). Functional aspects of mononuclear phagocyte involvment in lung inflammation. Ann. NY Acad. Sci. 465, 6-14.
30. SAMANIEGO, L.A., WEBB, A.L., and DELUCA, N.A. (1995). Functional interactions between herpes simplex virus immediate-early proteins during infection: Gene expression as a consequence of ICP27 and different domains of ICP4. J. Virol. 69, 5705-5715.
31. VAN FURTH, R., SLUITER, W., and VAN DISSEL, J.T. (1986). Genetic control of macrophage responses. Ann. NY Acad. Sci. 465, 15-25.
32. VAN OUD ALBLAS, A., and VAN FURTH, R. (1979). Origin, kinetics, and characteristics of pulmonary macrophages in the normal steady state. J. Exp. Med. 149, 1504-1518.
33. VOLBERDING, P.A., LAGAKOS, S.W., KOCH, M.A., PETTINELLI, C., MYERS, M.W., BOOTH, D.K., BALFOUR, H.H., REICHMAN, R.C., BARTLETT, J.A., HIRSCH, M.S., MURPHY, R.L., HARDY, W.D., SOEIRO, R., FISCHL, M.A., BARTLETT, J.G., MERIGAN, T.C., HYSLOP, N.E., RICHMAN, D.D., VALENTINE, F.T., COREY, L., and AIDS CLINICAL TRIALS GROUP. (1990). Zidovudine in asymptomatic human immunodeficiency virus infection: A controlled trial in persons with fewer than 500 CD4-positive cells per cubic millimeter. N. Engl. J. Med. 322, 941-949.
34. WEIR, J.P., and DACQUEL, E.J. (1995). Plasmid insertion vectors that facilitate construction of herpes simplex virus gene delivery vectors. Gene 154, 123-128.
35. WEIR, J.P., and ELKINS, K.L. (1993). Replication-incompetent herpesvirus vector delivery of an interferon alpha gene inhibits human immunodeficiency virus replication in human monocytes. Proc. Natl. Acad. Sci. USA 90, 9140-9144.
36. WEIR, J.P., and MELTZER, M.S. (1993). Transfection of human immunodeficiency virus type 1 proviral DNA into primary human monocytes. Cell. Immunol. 148, 157-165.
37. YU, M., POESCHLA, E., and WONG-STAAL, F. (1994). Progress towards gene therapy for HIV infection. Gene Ther. 1, 13-26.