Immunological aspects of nitric oxide in HIV-1 infection

Medical Hypotheses

Volumn 47, Issue 5, 1996, Pages 405-407

  Torre, D ^a   Ferrario, G ^a  

^a OSPEDALE DI CIRCOLO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE;

CELLULAR IMMUNITY; HOST RESISTANCE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPOTHESIS; IMMUNOSUPPRESSIVE TREATMENT; MACROPHAGE; PRIORITY JOURNAL; REVIEW;

FUNGI; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; PROTOZOA;

EID: 0029798758     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(96)90221-2     Document Type: Article

References (37)

1. Moncada S, Palmer R M, Hibbs E A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991; 43: 109-142.
2. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992; 6: 3051-3064.
3. Green S J, Nacy C A, Meltzer M S. Cytokine-induced synthesis of nitrogen oxides in macrophages: a protective host response to Leishmania and other intracellular pathogens. J Leukocyte Biol 1991; 50: 93-103.
4. Marletta M A. Nitric oxide: biosynthesis and biological significance. Trends Biochem Sci 1989; 14: 488-492.
5. Adams L B, Hibbs J B Jr, Taintor R R, Krahenbuhl J L. Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii: role for synthesis of inorganic nitrogen oxides from L-arginine. J Immunol 1990; 144: 2725-2729.
6. Granger D L, Hibbs J B Jr, Perfect J R, Durack D T. Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages. J Clin Invest 1990; 85: 264-273.
7. Evans T G, Thai L, Vavrin Z, Hibbs J B Jr. Effect of systemic inhibition of nitric oxide production in murine Leishmaniasis. J Immunol 1993; 151: 907-915.
8. Denis M. Interferon gamma treated murine macrophages inhibit growth of tubercle bacilli via the generation of reactive nitrogen intermediates. Cell Immunol 1991; 132: 150-157.
9. Alspaugh J A, Granger D L. Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis. Infect Immun 1991; 59: 2291-2296.
10. Croen K D. Evidence for an antiviral effect of nitric oxide. J Clin Invest 1993; 91: 2446-2452.
11. Hibbs J B, Vavrin Z, Taintor R R. L-arginine is required for the expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells. J Immunol 1987; 138: 550-565.
12. McCall T B, Boughton-Smith N K, Palmer R M, Whittle B J R, Moncada S. Synthesis of nitric oxide from L-arginine by neutrophils. Biochem J 1989; 261: 293-296.
13. Kirk S J, Regan M C, Barbul A. Cloned murine T lymphocytes synthesize a molecule with the biological characteristics of nitric oxide. Biochem Biophys Res Commun 1990; 173: 660-665.
14. Fauci A S. The human immunodeficiency virus: infectivity and mechanisms of pathogenesis. Science 1988; 239: 617-622.
15. Meltzer M S, Skillman D R, Gomatos P J, Kalter D C, Gendelman H E. Role of mononuclear phagocytes in the pathogenesis of human immunodeficiency virus infection. Annu Rev Immunol 1990; 8: 169-194.
16. Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med 1993; 329: 2002-2012.
17. Kolb H, Kolb-Bachofen V. Nitric oxide: a pathogenetic factor in autoimmunity. Immunol Today 1992; 13: 157-160.
18. Nathan C, Xie Q W. Nitric oxide synthases: roles, tolls, and controls. J Biol Chem 1994; 269: 13 725-13 728.
19. Heiss L N, Lancaster J R Jr, Corbett J A, Goldman W E. Epithelial autotoxicity of nitric oxide: role in the respiratory cytopathology of pertussis. Proc Natl Acad Sci USA 1994; 91: 267-270.
20. Oswald I P, Eltoum I, Wynn T A et al. Endothelial cells are activated by cytokine treatment to kill an intravascular parasite, Schistosoma mansoni, through the production of nitric oxide. Proc Natl Acad Sci USA 1994; 91: 999-1003.
21. Sicher S C, Vazquez M A, Lu C Y. Inhibition of macrophage Ia expression by nitric oxide. J Immunol 1994; 153: 1293-1300.
22. Fu Y, Blankehorn E P. Nitric oxide-induced antimitogenic effects in high and low responder rat strains. J Immunol 1992; 148: 2217-2223.
23. Isobe K, Nakashima I. Feedback suppression of staphylococcal enterotoxin-stimulated T-lymphocyte proliferation by macrophages through inductive nitric oxide synthesis. Infect Immun 1992; 60: 4832-4837.
24. Mills C D. Molecular basis of suppressor macrophages: arginine metabolism via the nitric oxide synthetase pathway. J Immunol 1991; 146: 2719-2723.
25. Holt P G, Oliver J, Bilyk N, McMenamin C, Kraal McMenamin G, Thepen T. Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages. J Exp Med 1993; 177: 397-313.
26. Torre D, Ferrario G, Bonetta G, Zeroli C, Giola M, Fiori G P. The role of nitric oxide in patients with HIV-1 infection. In: Tenth International Conference on AIDS, International Conference on STD, 7-12 August 1994, Yokohama, Japan, abstract PAO114. J Clin Pathol 1996; in press.
27. Evans T G, Rasmussen K, Wiebke G, Hibbs J B. Nitric oxide synthesis in patients with advanced HIV infection. Clin Exp Immunol 1994; 97: 83-86.
28. Zangerle R, Fuchs D, Reibnegger G et al. Serum nitrite plus nitrate in infection with human immunodeficiency virus type 1. Immunobiology 1995; 193: 59-70.
29. Pietraforte D, Tritarelli E, Testa U, Minetti M. gp 120 HIV envelope glycoprotein increases the production of nitric oxide in human monocyte-derived macrophages. J Leukocyte Biol 1994; 55: 175-182.
30. Torre D, Ferrario G, Bonetta G, Speranza F, Zeroli C. Production of nitric oxide from peripheral blood mononuclear cells and polymorphonuclear leukocytes of patients with HIV-1 infection. AIDS 1995; 9: 979-980.
31. Bukrinsky M I, Nottet H S L M, Schmidtmayerova H et al. Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease. J Exp Med 1995; 181: 735-745.
32. Dawson V L, Dawson T M, Uhl G R, Snyder S H. Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures. Proc Natl Acad Sci USA 1993; 90: 3256-3259.
33. Morgan M J, Kimes A S, London E D. Possible roles for nitric oxide in AIDS and associated pathology. Med Hypotheses 1992; 38: 189-193.
34. Vago L, Antonacci M C, Cristina S et al. Morphogenesis, evolution and prognostic significance of lymphatic tissue lesions in HIV infection. Appl Pathol 1989; 7: 298-309.
35. Albina J E, Abate J A, Henry WL. Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation. Role of IFN-gamma in the induction of the nitric oxide-synthesizing pathway. J Immunol 1991; 147: 144-148.
36. Takagi K, Nukaya I, Yasukawa K, Suketa Y. Inhibitory mechanisms of antibody production by nitrogen oxides released from activated macrophages during the immune response: relationship to energy consumption. Immunol Cell Biol 1994; 72: 241-248.
37. Eisenstein T K, Huang D, Meissler J J, Al-Ramadi B. Macrophage nitric oxide mediates immunosuppression in infectious inflammation. Immunobiology 1994; 191: 493-502.