GABAergic and asymmetrical synapses on somata of GABAergic neurons in CA1 and CA3 regions of rat hippocampus: A quantitative electron microscopic analysis

Stroke

Volumn 27, Issue 8, 1996, Pages 1411-1416

  Yao, Zhi B ^a   Li, Xiaoda ^a   Xu, Zao C ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

cerebral ischemia; excitotoxicity; GABA; rats; selective vulnerability

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BIOPSY; CELL SURVIVAL; ELECTRON MICROSCOPY; HIPPOCAMPUS; HISTOPATHOLOGY; MALE; NERVE CELL DEGENERATION; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPSE; TRANSIENT ISCHEMIC ATTACK;

EID: 0029798339     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.27.8.1411     Document Type: Article

References (42)

1. Kunkle DD, Hendrickson AE, Wu JY, Schwartzkroin PA. Glutamic acid decarboxylase (GAD) immunocytochemistry of developing rabbit hippocampus. J Neurosci. 1986;6:541-552.
2. Somogyi P, Hodgson AJ, Smith AD, Nunzi MG, Gorio A, Wu JV. Glutamate decarboxylase immunoreactivity in the hippocampus of the cat: distribution of immunoreactive synaptic terminals with special reference to the axon initial segment of pyramidal neurons. J Neurosci. 1983;3:1450-1468.
3. Andersen P, Eccles JS, Loyning Y. Location of postsynaptic inhibitory synapses of hippocampal pyramids. J Neurophysiol 1964;27: 592-607.
4. Frotscher M, Léránth CS, Lubbers K, Oertel WH. Commissural afferents innervate glutamate decarboxylase immuno-reactive non-pyramidal neurons in the guinea pig hippocampus. Neurosci Lett. 1984;46:137-143.
5. Spencer WA, Kandel ER. Hippocampal neurons responses to selective activation of recurrent collaterals of hippocampofugal axons. Exp Neurol. 1961;4:149-161.
6. Alger BE, Nicoll RA. Feed-forward inhibition in rat hippocampal pyramidal cells studied in vitro. J Physiol (Lond). 1982;328: 105-123.
7. Ribak CE, Vaughn JE, Saito K. Immunocytochemical localization of glutamic acid decarboxylase in neuronal somata following colchicine inhibition of axonal transport. Brain Res. 1987;140:315-332.
8. Kirino H. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 1982;239:57-69.
9. Pulsinelli WA, Brierly JB, Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol 1982;11:499-509.
10. Choi DW, Rothman SM. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci. 1990;13: 171-182.
11. Globus MY-T, Busto R, Martinez E, Valdes I, Dietrich WD, Ginsberg MD. Comparative effect of transient global ischemia on extra-cellular levels of glutamate, glycine, and gamma-aminobutyric acid in vulnerable and nonvulnerable brain regions in the rat. J Neurochem. 1991;57:470-478.
12. Lyden PD, Hedges B. Protective effect of synaptic inhibition during cerebral ischemia in rats and rabbits. Stroke. 1992;23: 1463-1470.
13. Ravindran J, Shuaib A, Ijaz S, Galazka P, Waqar T, Ishaqzay R, Miyashita H, Liu L. High extracellular GABA levels in hippocampus - as a mechanism of neuronal protection in cerebral ischemia in adrenalectomized gerbils. Neurosci Lett. 1994;176:209-211.
14. Johansen FF, Diemer NH. Enhancement of GABA neurotransmission after cerebral ischemia in the rat reduces loss of hippocampal CA1 pyramidal cells. Acta Neurol Scand. 1991;84:1-6.
15. Madden KP. Effect of gamma-aminobutyric acid modulation on neuronal ischemia in rabbits. Stroke. 1994;25:2271-2275.
16. Schwartz RD, Huff RA, Yu X, Carter ML, Bishop M. Postischemic diazepam is neuroprotective in the gerbil hippocampus. Brain Res. 1994;647:153-160.
17. Sternau LL, Lust WD, Ricci AJ, Ratcheson R. Role for γ-aminobutyric acid in selective vulnerability in gerbils. Stroke. 1989;20: 281-287.
18. Johansen FF, Lin CT, Schouboe A, Wu JY. Immunocytochemical investigation of L-glutamate acid decarboxylase in the rat hippocampal formation: the influence of transient cerebral ischemia. J Comp Neurol. 1989;281:40-53.
19. Nitsch C, Coping G, Klatzo I. Preservation of GABAergic perikarya and boutons after transient ischemia in the gerbil hippocampal CA1 field. Brain Res. 1989;495:243-252.
20. Schiander M, Hoyer S, Frotscher M. Glutamate decarboxylase-immunoreactive neurons in the aging rat hippocampus are more resistant to ischemia than CA1 pyramidal cells. Neurosci Lett. 1988; 91:241-246.
21. Krnjevic K, Xu YZ, Zhang L. Anoxic block of GABAergic IPSPs. Neurochem Res. 1991;16:279-284.
22. Xu ZC, Pulsinelli WA. Responses of CA1 pyramidal neurons in rat hippocampus to transient forebrain ischemia: an in vivo intracellular recording study. Neurosc Lett. 1994; 171:187-191.
23. Zhang L, Krnjevic K. Whole-cell recording of anoxic effects on hippocampal neurons in slices. J Neurophysiol. 1993;69:118-128.
24. Xu ZC, Pulsinelli WA. Electrophysiological changes of CA1 neurons after transient ischemia: an in vivo intracellular recording study. J Cereb Blood Flow Metab. 1995;15(suppl 1):S194. Abstract.
25. Congar P, Khazipov R, Ben-Ari Y. Direct demonstration of disconnection by anoxia inhibitory interneurons from excitatory inputs in rat hippocampus. J Neurophysiol. 1995;73:421-426.
26. Franck JE, Kunkel DD, Akin DGB, Schwartzkroin PA. Inhibition in kainate-lesioned hyperexcitable hippocampi: physiologic, autoradiographic and immunocytochemical observations. J Neurosci. 1988; 8:1991-2002.
27. Yao ZB, Li ZC, Xu ZC. Different distribution of GABAergic components between CA1 and CA3 region in rat hippocampus. Soc Neurosci Abstr. 1995;393:17. Abstract.
28. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. 2nd ed. London, UK: Academic Press; 1989.
29. Buhl EH, Halasy K, Somogyi P. Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites. Nature. 1994;368:823-828.
30. Kawaguchi Y, Hama K. Physiological heterogeneity of nonpyramidal cells in rat hippocampal CA1 region. Exp Brain Res. 1988;72: 494-502.
31. Lorente de Nó R. Studies on the structure of the cerebral cortex: continuation of the study of the ammonic system. J Psychol Neural (Leipz). 1934;46:113-177.
32. Woodson W, Nitecka L, Ben-Ari Y. Organization of the GABAergic system in the rat hippocampal formation: a quantitative immunocytochemical study. J Comp Neurol. 1989;280:254-271.
33. Köhler C, Chan-Palay V. Gamma-aminobutyric acid interneurons in the rat hippocampal region studied by retrograde transport of glutamic acid decarboxylase antibody after in vivo injections. Anat Embryol (Berl). 1983;163:53-66.
34. Farias PA, Low SQ, Peterson GM, Ribak CE. Morphological evidence for altered synaptic organization and structure in the hippocampal formation of seizure-sensitive gerbils. Hippocampus. 1992;2:229-246.
35. Roberts E. Role of GABA in neurons in information processing in the vertebrate CNS. In: Karlin A, Tennyson VM, Vogel HJ, eds. Neuronal Information Transfer. New York, NY: P&S Biomedical Sciences Symposia; 1978:213-239.
36. Roberts E. GABA neuron in the mammalian central nervous system: model for a minimal basic neural unit. Neurosci Lett. 1984;47: 195-200.
37. Johnston D, Brown TH. Giant synaptic potential hypothesis for epileptiform activity. Science. 1981;211:294-297.
38. Johnston D, Brown TH. Mechanisms of neuronal burst generation. In: Schwartzkroin PA, Wheal HV, eds. Electrophysiology of Epilepsy. New York, NY: Academic Press Inc; 1984:277-301.
39. Fujiwara N, Higashi H, Shimoji K, Yoshimura M. Effects of hypoxia on rat hippocampal neurones in vitro. J Physiol (Land). 1987; 384:131-151.
40. Leblond J, Krnjevic K. Hypoxic changes in hippocampal neurons. J Neurophysiol. 1989;62:1-14.
41. Chang HS. Sasaki T, Kassell NF. Hippocampal unit activity after transient ischemia in rats. Stroke. 1989;20:1051-1058.
42. Kawasaki K, Traynelis SF, Dingledine R. Different responses of CA1 and CA3 regions to hypoxia in rat hippocampal slice. J Neurophysiol. 1990;63:385-394.