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2 or its reverse. "Acetyl-CoA synthase" (ACS) is the recommended name for the activity that assembles acetyl-CoA from enzyme-bound methyl, CO, and CoA groups. The bifunctional enzyme from acetogens and methanogens is designated "CO dehydrogenase/acetyl-CoA synthase" (CODH/ACS); the monofunctional enzyme from R. rubrum is denoted CODH [Ragsdale, S. W.; Kumar, M. Chem. Rev. In press].
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