Modified lipoproteins, cytokines and macrovascular disease in non-insulin-dependent diabetes mellitus

Annals of Medicine

Volumn 28, Issue 4, 1996, Pages 347-354

  Lopes Virella, Maria F ^a,b   Virella, Gabriel ^b  

^a MUSC Medical Center   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Cytokines; Endothelium damage; Glycation; LDL immune complexes; Macrophages; Oxidation

Indexed keywords

CHOLESTEROL ESTER; CYTOKINE; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; STRUCTURAL PROTEIN;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL WALL; ENDOTHELIUM CELL; ENDOTHELIUM LESION; FOAM CELL; GLYCATION; LIPOPROTEIN METABOLISM; MACROPHAGE; MACROPHAGE ACTIVATION; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATION; PRIORITY JOURNAL; THROMBOCYTE;

EID: 0029796452     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.3109/07853899608999092     Document Type: Article

References (25)

1. Bucala R, Makita Z, Koschinsky T, Cermi A, Vlassara H. Lipid advanced glycation: pathway for lipid oxidation in vivo. Proc Natl Acad Sci USA 1993; 90: 6434-8.
2. Wolff SP, Dean RT. Glucose autoxidation and protein modification: the potential role of 'autoxidative glycation' in diabetes mellitus. Biochem J 1987; 245: 243-50.
3. Sakurai T, Kimura S, Nakano M, Kimura H. Oxidative modification of glycated low density lipoprotein in the presence of iron. Biochem Biophys Res Commun 1991; 177: 433-9.
4. Hunt JV, Smith CCT, Wolff, SP. Autooxidative glycation and possible involvement of peroxides and free radicals in LDL modification by glucose. Diabetes 1990; 39: 1420-4.
5. Kawamura M, Heinecke JW, Chait A. Pathiphysiological concentrations of glucose promote oxidative modification of LDL by a superoxide-dependent pathway. J Clin Invest 1994; 94: 771-8.
6. Mullarkey CJ, Edelstein D, Brownlee M. Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochem Biophys Res Commun 1990; 173: 932-9.
7. Brownlee M, Vlassara H, Cerami A. Nonenzymatic glycosylation products on collagen covalently trap low-density lipoprotein. Diabetes 1985; 34: 938-41.
8. Schleicher E, Deufel T, Wieland OH. Non-enzymatic glycation of human serum lipoproteins. FEBS Lett 1987; 129: 1-4.
9. Lyons TJ, Patrick JS, Baynes JW, Colwell JA, Lopes-Virella MF. Glycation of low density lipoprotein in patients with Type 1 diabetes: correlations with other parameters of glycaemic control. Diabetologia 1986; 29: 685-9.
10. Gonen B, Baenziger J, Schonfeld G, Jacobsen D, Farrar P. Non-enzymatic glycation of low-density lipoproteins in vitro. Diabetes 1981; 30: 875-8.
11. Witztum JL, Mahoney EM, Branks MJ, Fisher M, Elam R, Steinberg D. Nonenzymatic glucosylation of low-density lipoprotein alters its biologic activity. Diabetes 1982; 31: 283-91.
12. Sasaki J, Cottam GL. Glycation of LDL decreases its ability to interact with high-affinity receptors of human fibroblasts in vitro and decreases its clearance from rabbit plasma in vivo. Biochim Biophys Acta 1982; 713: 199-207.
13. Steinbrecher UP, Witztum JL. Glucosylation of low density lipoproteins to an extent comparable to that seen in diabetes slows their catabolism. Diabetes 1984; 33: 130-4.
14. Lopes-Virella MF, Klein RL, Lyons TJ, Stevenson HC, Witztum JL. Glycation of low-density lipoprotein enhances cholesteryl ester synthesis in human monocyte-derived macrophages. Diabetes 1988; 37: 550-7.
15. Lyons TJ, Klein R L, Baynes JW, Stevenson HC, Lopes-Virella MF. Stimulation of cholesteryl ester synthesis in human monocyte-derived macrophages by low-density lipoproteins from type I (insulin-dependent) diabetic patients: the influence of non-enzymatic glycation of low-density lipoprotein. Diabetologia 1987; 30: 916-23.
16. Klein RL, Laimins M, Lopes-Virella MF. Isolation, characterization, and metabolism of the glycated and nonglycated subfractions of low-density lipoproteins isolated from type 1 diabetic patients and nondiabetic subjects. Diabetes 1995; 44: 1093-8.
17. Jack CM, Sheridan B, Kennedy L, Stout RW. Non-enzymatic glycation of low-density lipoprotein. Results of an affinity chromatography method. Diabetologia 1988; 31: 126-8.
18. Klein RL, Lyons TJ, Lopes-Virella MF. Metabolism of very low- and low density lipoproteins isolated from normolipidaemic Type 2 (non-insulin-dependent) diabetic patients by human monocyte-derived macrophages. Diabetologia 1990; 33: 299-305.
19. Watanabe J, Wohltmann HJ, Klein RL, Colwell JA, Lopes-Virella MF. Enhancement of platelet aggregation by low density lipoproteins from IDDM patients. Diabetes 1988; 37: 1652-7.
20. Freeman M, Ekkel Y, Rohrer L. Expression of type I and Type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and non-reciprocal cross competition by acetylated and oxidized LDL. Proc Natl Acad Sci USA 1991; 88: 4931-6.
21. Arai K, Kita T, Yokode M, Narumiya S, Kawai C. Multiple receptors for modified LDL in mouse peritoneal macrophages: different uptake mechanisms for acetylated and oxidized LDL. Biochem Biophys Res Commun 1989; 159: 1375-9.
22. Sparrow CP, Parthasarathy S, Steinberg D. A macrophage receptor that recognizes oxidized LDL but not acetylated LDL. J Biol Chem 1989; 264: 2599-603.
23. Fogelman AM, Schechter I, Seager J, Hokom M, Child JS, Edwards PA. Malondialdehyde alteration of LDL leads to cholesterol ester accumulation in human monocytes/ macrophages. Proc Natl Acad Sci USA 1980; 77: 2214-8.
24. Cazzolato G, Avogaro P, Bittolo-Bon G. Characterization of a more electronegatively charged LDL subfraction by ion exchange HPLC. Free Radic Biol Med 1991; 11: 247-53.
25. Ylä-Herttuala S, Palinski W, Rosenfeld ME, et al. Evidence for the presence of oxidatively modified LDL in atherosclerotic lesions of rabbit and man. J Clin Invest 1989; 84: 1086-95.