Neighboring group catalysis in the design of nucleotide prodrugs

Journal of Medicinal Chemistry

Volumn 39, Issue 20, 1996, Pages 4109-4115

  Khamnei, Shahrzad ^a   Torrence, Paul F ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' DIDEOXYTHYMIDINE; ESTERASE; NUCLEOTIDE DERIVATIVE; PHOSPHORUS ACID DERIVATIVE; PRODRUG; SALICYLIC ACID DERIVATIVE; ZIDOVUDINE DERIVATIVE;

ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; BRAIN; CATALYSIS; CONTROLLED STUDY; DRUG DESIGN; DRUG HYDROLYSIS; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LIVER; NONHUMAN; RAT; SERUM;

ANIMALS; BRAIN; CATALYSIS; DRUG DESIGN; ESTERASES; GLUCOSE; HUMANS; HYDROLYSIS; KINETICS; LIVER; PRODRUGS; RATS; SALICYLIC ACID; SALICYLIC ACIDS; SWINE; THYMIDINE MONOPHOSPHATE; ZIDOVUDINE;

EID: 0029796135     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9600757     Document Type: Article

References (23)

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