Randomized cross-over study of adverse reactions and cost implications of intravenous push compared with infusion of iron dextran in hemodialysis patients

American Journal of Kidney Diseases

Volumn 28, Issue 4, 1996, Pages 523-528

  St Peter, Wendy L ^a,b   Lambrecht, Lawrence J ^a   Macres, Mark ^a  

^a HENNEPIN COUNTY MEDICAL CENTER   (United States)

^b Drug Evaluation Unit   (United States)

Author keywords

adverse effects; cost minimization; Iron dextran

Indexed keywords

IRON DEXTRAN;

ADULT; ARTHRALGIA; ARTICLE; CHILL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; CROSSOVER PROCEDURE; DRUG EFFECT; FEMALE; FEVER; HEADACHE; HEMODIALYSIS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; IRON DEFICIENCY ANEMIA; MAJOR CLINICAL STUDY; MALE; MUSCLE WEAKNESS; NAUSEA; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RASH; ULTRAFILTRATION; VERTIGO; VOMITING;

EID: 0029796031     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0272-6386(96)90462-X     Document Type: Article

References (6)

1. Watson A: Iron management during treatment with recombinant human erythropoietin in chronic renal failure. J Clin Pharmacol 33:1134-1138, 1993
2. Van Wyck DB: Iron dextran in chronic renal failure. Semin Dial 4:112-114, 1991
3. Hatton RC, Portales IT, Ross EA: Removal of iron dextran by hemodialysis: An in vitro study. Am J Kidney Dis 26:327-330, 1995
4. Kumpf VJ, Holland EG: Parenteral iron dextran therapy. DICP Ann Pharmacother 24:162-166, 1990
5. Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H: Clinical use of the total dose intravenous infusion of iron dextran. J Lab Clin Med 111:566-570, 1988
6. Rault R, Nespor S, Holley J: Safety and efficacy of 500 mg of iron-dextran as a single IV infusion in patients on chronic dialysis. ASAIO J 23:74, 1994 (abstr)