Increased levels of extracellular noradrenaline in the frontal cortex of rats exposed to naturalistic environmental stimuli: Modulation by acute systemic administration of diazepam or buspirone

Psychopharmacology

Volumn 127, Issue 1, 1996, Pages 47-54

  Dalley, J W ^a   Mason, K ^a   Stanford, S C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Buspirone; Diazepam; Frontal cortex; In vivo microdialysis; Noradrenaline; Novelty; Stress

Indexed keywords

ANXIOLYTIC AGENT; BUSPIRONE; DIAZEPAM; NORADRENALIN;

ANIMAL EXPERIMENT; AROUSAL; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; FRONTAL CORTEX; INTRAPERITONEAL DRUG ADMINISTRATION; LOCOMOTION; MALE; MICRODIALYSIS; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; STRESS;

EID: 0029795632     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02805974     Document Type: Article

References (34)

1. 3-antagonists and benzodiazepines: their comparative behavioural pharmacology. Wiley, Chichester, New York, Brisbane, Toronto, Singapore, pp 59-105
2. 1A agonists uncouple noradrenergic somatodendritic impulse flow and terminal release. Brain Res Bull 27:693-696
3. Cadogen AK, Kendall DA, Fink H, Marsden CA (1994) Social interaction increases 5-HT release and cAMP efflux in the rat central hippocampus. Behav Pharmacol 5:299-305
4. Dalley JW, Stanford SC (1994) Graded changes in noradrenaline (NA) efflux in dialysates of rat cortex evoked by non-noxious stressors. J Psychopharmacol 8 [Suppl]: 188
5. Dalley JW, Stanford SC (1995a) Incremental changes in extracellular noradrenaline availability in the frontal cortex induced by naturalistic environmental stimuli: a microdialysis study in the freely-moving rat. J Neurochem 65:2644-2651
6. 2-adrenoceptor agonists, medetomidine, clonidine and UK 14304 on extraneuronal levels of noradrenaline in the rat frontal cortex: evaluation using in vivo microdialysis and synaptosomal uptake studies. Br J Pharmacol 114: 1717-1723
7. 2 receptors: microdialysis studies in the awake and anaesthetized rat. Neuropharmacology 33:411-421
8. 1A receptor agonists and NMDA receptor antagonists in the social interaction test and the elevated plus maze. Eur J Pharmacol 169:1-10
9. 2-receptor blockade. J Neural Transm 76:91-98
10. File SE, Hyde JRG (1978) Can social interaction be used to measure anxiety? Br J Pharmacol 62:19-24
11. Finlay JM, Zigmond MJ, Abercrombie ED (1995) Increased dopamine and norepinephrine release in medial prefrontal cortex induced by acute and chronic stress: effects of diazepam. Neuroscience 64:619-628
12. Fuller RW, Perry KW (1989) Effects of buspirone and its metabolite, 1-(2-pyrimidinyl)piperazine, on brain monoamines and their metabolites in rats. J Pharmacol Exp Ther 248:50-56
13. Gobbi M, Frittoli E, Mennini T (1990) Antagonist properties of 1-(2-pyrimidinyl)piperazine at presynaptic 22-adrenoceptors in the rat brain. Eur J Pharmacol 180:183-196
14. Grant SJ, Aston-Jones G, Redmond DE (1988) Responses of primate locus coeruleus neurons to simple and complex sensory stimuli. Brain Res Bull 21:401-410
15. Ida Y, Tanaka M, Tsuda A, Tsujimaru S, Nagasaki S (1985) Attenuating effect of diazepam on stress-induced increases in noradrenaline turnover in specific brain regions of rats: antagonism by Ro 15-1788. Life Sci 37:2491-2498
16. Nakane H, Shimizu N, Hori T (1994) Stress-induced norepinephrine release in the rat prefrontal cortex measured by microdialysis. Am J Physiol 267:R1559-1566
17. Norusis MJ (1990) Advanced statistics user's guide. SPSS Inc., Chicago
18. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates. Academic Press, London
19. 1A agonists correlates with dopamine antagonist properties. J Pharmacol Exp Ther 268:1297-1303
20. Rajkowski J, Kubiak P, Aston-Jones G (1994) Locus coeruleus activity in monkey: phasic and tonic changes are associated with altered vigilance. Brain Res Bull 35:607-616
21. Rasmussen K, Jacobs BL (1986) Single unit activity of locus coeruleus neurons in the freely-moving cat. II. Conditioning and pharmacologic studies. Brain Res 371:335-344
22. Rossetti ZL, Portas C, Pani L, Carboni S, Gessa GL (1990) Stress increases noradrenaline release in the rat frontal cortex: prevention by diazepam. Eur J Pharmacol 176:229-231
23. Sanghera MK, German DC (1983) The effects of benzodiazepine and non-benzodiazepine anxiolytics on locus coeruleus activity. J Neural Transm 57:267-279
24. Sara SJ, Segal M (1991) Plasticity of sensory responses of locus coeruleus neurons in the behaving rat: implications for cognition. Prog Brain Res 88:571-585
25. Stanford SC (1995) Central noradrenergic neurones and stress. Pharmacol Ther 68:297-342
26. Stanford SC (1996) Stress: a major variable in the psychopharmacological response. Pharmacol Biochem Behav 54:211-217
27. 1A receptor activation. Br J Pharmacol 115:703-711
28. Tatsuno T, Shimizu H, Hirose A, Tanuka H, Kumasaka Y, Nakamura M (1989) Effects of the putative anxiolytic SM-3997 on central monoaminergic systems. Pharmacol Biochem Behav 32:1049-1055
29. Taylor KM, Laverty R (1969) The effect of chlordiazepoxide, diazepam and nitrazepam on catecholamine metabolism in regions of the rat brain. Eur J Pharmacol 8:296-301
30. 3-antagonists and benzodiazepines: their comparative behavioural pharmacology. Wiley, Chichester, New York. Brisbane, Toronto, Singapore, pp 107-131
31. Tunnicliffe G (1991) Molecular basis of buspirone's anxiolytic action. Pharmacol Toxicol 69:149-156
32. Vahabzadeh A, Fillenz M (1994) Comparison of stress-induced changes in noradrenergic and serotonergic neurons in the rat hippocampus using microdialysis. Eur J Neurosci 6: 1205-1212
33. Wilkinson LO, Abererombie ED, Rasmussen K, Jacobs BL (1987) Effect of buspirone on single unit activity in locus coeruleus and dorsal raphe nucleus in behaving cats. Eur J Pharmacol 136:123-127
34. Yokoo H, Tanaka M, Yoshida M, Tsuda AS, Tanaka T, Mizoguchi K (1990) Direct evidence of conditioned fear-elicited enhancement of noradrenaline release in the rat hypothalamus assessed by intracranial microdialysis. Brain Res 536:305-308