Endothelin-1 in heart failure: A new therapeutic target?

Lancet

Volumn 348, Issue 9025, 1996, Pages 418-419

  Kaddoura, Sam ^a   Poole Wilson, Philip A ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CYTOKINE; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; MESSENGER RNA;

ADRENERGIC SYSTEM; DISEASE SEVERITY; HEART FAILURE; HEMODYNAMICS; HUMAN; MORTALITY; PATHOGENESIS; PRIORITY JOURNAL; PROGNOSIS; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SHORT SURVEY; SURVIVAL;

EID: 0029795438     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)64531-X     Document Type: Note

References (13)

1. Marguiles KB, Hildebrand FL, Lerman A, Perrela MA, Burnett JC Jr. Increased endothelin in experimental heart failure. Circulation 1990; 82: 2226-30.
2. Teerlink JR, Loffler BM, Hess P, Marie JP, Clozel M, Clozel JP. Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan). Circulation 1994; 90: 2510-18.
3. Hiroe M, Hirata Y, Fujita N, et al. Plasma endothelin-1 levels in idiopathic dilated cardiomyopathy. Am J Cardiol 1991; 68: 1114-15.
4. Stewart DJ, Cernacek P, Costello KB, Rouleau JL. Elevated endothelin-1 in heart failure and loss of the normal response to postural change. Circulation 1992; 85: 510-517
5. Cody RJ, Haas GJ, Binkley PF, Capers Q, Kelly R. Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure. Circulation 1992; 85: 504-09.
6. Pacher R, Bergler-Klein J, Globits S, et al. Plasma big endothelin-1 concentrations in congestive heart failure with or without systemic hypertension. Am J Cardiol 1993; 71: 1293-99.
7. McMurray JJ, Ray SG, Abdullah I, Dargie HJ, Morton JJ. Plasma endothelin in chronic heart failure. Circulation 1992; 85: 1374-79.
8. Wei CM, Lerman A, Rodeheffer RJ, et al. Endothelin in human congestive heart failure. Circulation 1994; 89: 1580-86.
9. Tsutamoto T, Wada A, Maeda Y, Adachi T, Kinoshita M. Relation between endothelin-1 spillover in the lungs and pulmonary vascular resistance in patients with chronic heart failure. J Am Coll Cardiol 1994; 23: 1427-33.
10. Pacher R, Stanek B, Hulsmann M, et al. Prognostic impact of big endothelin-1 plasma concentrations compared with invasive hemodynamic evaluation in severe heart failure. J Am Coll Cardiol 1996; 27: 633-41.
11. Krum H, Gu A, Wilshire-Clement M, et al. Changes in plasma endothelin-1 levels reflect clinical response to beta-blockade in chronic heart failure. Am Heart J 1996: 131: 337-41.
12. Krum H, Goldsmith R, Wilshire-Clement M, et al. Role of endothelin in the exercise intolerance of chronic heart failure. Am J Cardiol 1995; 75: 1282-83.
13. Kiowski W, Sutsch G, Huniziker P, et al. Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure. Lancet 1995; 346: 732-736.