메뉴 건너뛰기




Volumn 70, Issue 11, 1996, Pages 8055-8063

Inhibition of human immunodeficiency virus type 1 and type 2 Tat function by transdominant Tat protein localized to both the nucleus and cytoplasm

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; PROTEIN INHIBITOR; TRANSACTIVATOR PROTEIN;

EID: 0029795044     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.11.8055-8063.1996     Document Type: Article
Times cited : (25)

References (78)
  • 3
    • 0011093360 scopus 로고
    • Synthesis of the complete trans-activation gene product of human T-lymphotropic virus type III in Eschcrichia coli: Demonstration of immunogenicity in vivo and expression in vitro
    • Aldovini, A., C. Debouck, M. B. Feinberg, M. Rosenberg, S. K. Arya, and F. Wong-Staal. 1986. Synthesis of the complete trans-activation gene product of human T-lymphotropic virus type III in Eschcrichia coli: demonstration of immunogenicity in vivo and expression in vitro. Proc. Natl. Acad. Sci. USA 83:6672-6676.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 6672-6676
    • Aldovini, A.1    Debouck, C.2    Feinberg, M.B.3    Rosenberg, M.4    Arya, S.K.5    Wong-Staal, F.6
  • 4
    • 0023694470 scopus 로고
    • Human and simian immunodeficiency retroviruses: Activation and differential transactivation of gene expression
    • Arya, S. K. 1988. Human and simian immunodeficiency retroviruses: activation and differential transactivation of gene expression. AIDS Res. Hum. Retroviruses 4:175-186.
    • (1988) AIDS Res. Hum. Retroviruses , vol.4 , pp. 175-186
    • Arya, S.K.1
  • 6
    • 0021967217 scopus 로고
    • Trans-activator gene of human T-lymphotropic virus type III (HTLV-III)
    • Arya, S. K., C. Guo, S. F. Josephs, and F. Wong-Staal. 1985. Trans-activator gene of human T-lymphotropic virus type III (HTLV-III). Science 229:69-71
    • (1985) Science , vol.229 , pp. 69-71
    • Arya, S.K.1    Guo, C.2    Josephs, S.F.3    Wong-Staal, F.4
  • 8
    • 0025031783 scopus 로고
    • TAR-independent activation of the HIV-1 LTR: Evidence that tat requires specific regions of the promoter
    • Berkhout, B., A. Gatignol, A. B. Rabson, and K. T. Jeang. 1990. TAR-independent activation of the HIV-1 LTR: evidence that tat requires specific regions of the promoter. Cell 62:757-767.
    • (1990) Cell , vol.62 , pp. 757-767
    • Berkhout, B.1    Gatignol, A.2    Rabson, A.B.3    Jeang, K.T.4
  • 10
    • 0025169844 scopus 로고
    • Characterization of murine monoclonal antibodies to the Tat protein from human immunodeficiency virus type 1
    • Brake, D. A., J. Goudsmit, W. Krone, P. Schammel, N. Appelby, R. H. Meloen, and C. Debouck. 1990. Characterization of murine monoclonal antibodies to the Tat protein from human immunodeficiency virus type 1. J. Virol. 64:962-905.
    • (1990) J. Virol. , vol.64 , pp. 962-1905
    • Brake, D.A.1    Goudsmit, J.2    Krone, W.3    Schammel, P.4    Appelby, N.5    Meloen, R.H.6    Debouck, C.7
  • 11
    • 0025771419 scopus 로고
    • Identification of lentivirus tat functional domains through generation of equine infectious anemia virus/ human immunodeficiency virus type 1 tat gene chimeras
    • Carroll, R., L. Martarano, and D. Derse. 1991. Identification of lentivirus tat functional domains through generation of equine infectious anemia virus/ human immunodeficiency virus type 1 tat gene chimeras. J. Virol. 65:3460-3467.
    • (1991) J. Virol. , vol.65 , pp. 3460-3467
    • Carroll, R.1    Martarano, L.2    Derse, D.3
  • 12
    • 0026558060 scopus 로고
    • Inhibition of human immunodeficiency virus type 1 Tat activity by coexpression of heterologous trans activators
    • Carroll, R., B. M. Peterlin, and D. Derse. 1992. Inhibition of human immunodeficiency virus type 1 Tat activity by coexpression of heterologous trans activators. J. Virol. 66:2000-2007.
    • (1992) J. Virol. , vol.66 , pp. 2000-2007
    • Carroll, R.1    Peterlin, B.M.2    Derse, D.3
  • 13
    • 0027191817 scopus 로고
    • Does HIV-1 tat induce a change in viral initiation rights?
    • Cullen, B. R. 1993. Does HIV-1 tat induce a change in viral initiation rights? Cell 73:417-420.
    • (1993) Cell , vol.73 , pp. 417-420
    • Cullen, B.R.1
  • 15
    • 0028173857 scopus 로고
    • Construction and characterization of a potent HIV-2 tat transdominant mutant protein
    • Echetubu, C. O., H. Rhim, C. H. Herrmann, and A. P. Rice. 1994. Construction and characterization of a potent HIV-2 tat transdominant mutant protein. J. Acquired Immune Defic. Syndr. 7:655-664.
    • (1994) J. Acquired Immune Defic. Syndr. , vol.7 , pp. 655-664
    • Echetubu, C.O.1    Rhim, H.2    Herrmann, C.H.3    Rice, A.P.4
  • 16
    • 0023990358 scopus 로고
    • Tat protein from human immunodeficiency virus forms a metal-linked dimer
    • Frankel, A. D., D. S. Bredt, and C. O. Pabo. 1988. Tat protein from human immunodeficiency virus forms a metal-linked dimer. Science 240:70-73.
    • (1988) Science , vol.240 , pp. 70-73
    • Frankel, A.D.1    Bredt, D.S.2    Pabo, C.O.3
  • 17
    • 0023681468 scopus 로고
    • Dimerization of the tat protein from human immunodeficiency virus: A cysteine-rich peptide mimics the normal metal-linked dimer interface
    • Frankel, A. D., L. Chen, R. J. Cotter, and C. O. Pabo. 1988. Dimerization of the tat protein from human immunodeficiency virus: a cysteine-rich peptide mimics the normal metal-linked dimer interface. Proc. Natl. Acad. Sci. USA 85:6297-6300.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6297-6300
    • Frankel, A.D.1    Chen, L.2    Cotter, R.J.3    Pabo, C.O.4
  • 18
    • 0029055286 scopus 로고
    • Identification of a novel human zinc linger protein that specifically interacts with the activation domain of lentiviral Tat proteins
    • Fridell, R. A., L. S. Harding, H. P. Bogerd, and B. R. Cullen. 1995. Identification of a novel human zinc linger protein that specifically interacts with the activation domain of lentiviral Tat proteins. Virology 209:347-357.
    • (1995) Virology , vol.209 , pp. 347-357
    • Fridell, R.A.1    Harding, L.S.2    Bogerd, H.P.3    Cullen, B.R.4
  • 19
    • 0024095588 scopus 로고
    • Functional domains required for tat-induced transcriptional activation of the HIV-1 long terminal repeat
    • Garcia, J. A., D. Harrich, L. Pearson, R. Mitsuyasu, and R. B. Gaynor. 1988. Functional domains required for tat-induced transcriptional activation of the HIV-1 long terminal repeat. EMBO J. 7:3143-3147.
    • (1988) EMBO J. , vol.7 , pp. 3143-3147
    • Garcia, J.A.1    Harrich, D.2    Pearson, L.3    Mitsuyasu, R.4    Gaynor, R.B.5
  • 20
    • 0027136214 scopus 로고
    • Synergism between tat and VP16 in trans-activation of HIV-1 LTR
    • Ghosh, S., M. J. Selby, and B. M. Peterlin. 1993. Synergism between tat and VP16 in trans-activation of HIV-1 LTR. J. Mol. Biol. 234:610-619.
    • (1993) J. Mol. Biol. , vol.234 , pp. 610-619
    • Ghosh, S.1    Selby, M.J.2    Peterlin, B.M.3
  • 21
    • 0020435972 scopus 로고
    • Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells
    • Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044-1051.
    • (1982) Mol. Cell. Biol. , vol.2 , pp. 1044-1051
    • Gorman, C.M.1    Moffat, L.F.2    Howard, B.H.3
  • 22
    • 0015857646 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham, F. L., and A. J. van der eb. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 54:536-539.
    • (1973) Virology , vol.54 , pp. 536-539
    • Graham, F.L.1    Van Der Eb, A.J.2
  • 23
    • 0024392386 scopus 로고
    • Mutational analysis of HIV-1 Tat minimal domain peptides: Identification of trans-dominant mutants that suppress HIV-LTR-driven gene expression
    • Green, M., M. Ishino, and P. M. Loewenstein. 1989. Mutational analysis of HIV-1 Tat minimal domain peptides: identification of trans-dominant mutants that suppress HIV-LTR-driven gene expression. Cell 58:215-223.
    • (1989) Cell , vol.58 , pp. 215-223
    • Green, M.1    Ishino, M.2    Loewenstein, P.M.3
  • 24
    • 0023657622 scopus 로고
    • Genome organization and transactivation of the human immunodeficiency virus type 2
    • Guyader, M., M. Emerman, P. Sonigo, F. Clavel, L. Montagnier, and M. Alizon. 1987. Genome organization and transactivation of the human immunodeficiency virus type 2. Nature (London) 326:662-669.
    • (1987) Nature (London) , vol.326 , pp. 662-669
    • Guyader, M.1    Emerman, M.2    Sonigo, P.3    Clavel, F.4    Montagnier, L.5    Alizon, M.6
  • 25
    • 10244247288 scopus 로고
    • Manipulation of SV40 vectors
    • E. J. Murray (ed.), The Humana Press, Inc., Clifton, N.J.
    • Hammarskjöld, M.-L. 1991. Manipulation of SV40 vectors, p. 169-180. In E. J. Murray (ed.), Methods in molecular biology. The Humana Press, Inc., Clifton, N.J.
    • (1991) Methods in Molecular Biology , pp. 169-180
    • Hammarskjöld, M.-L.1
  • 26
    • 0026323411 scopus 로고
    • Transactivation of heterologous promoters by HIV-1 tat
    • Han, P., R. Brown, and J. Barsoum. 1991. Transactivation of heterologous promoters by HIV-1 tat. Nucleic Acids Res. 19:7225-7229.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 7225-7229
    • Han, P.1    Brown, R.2    Barsoum, J.3
  • 27
    • 0025639004 scopus 로고
    • TAR-independent activation of the human immunodeficiency virus in phorbol ester stimulated T lymphocytes
    • Harrich, D., J. Garcia, R. Mitsuyasu, and R. Gaynor. 1990. TAR-independent activation of the human immunodeficiency virus in phorbol ester stimulated T lymphocytes. EMBO J. 9:4417-4423.
    • (1990) EMBO J. , vol.9 , pp. 4417-4423
    • Harrich, D.1    Garcia, J.2    Mitsuyasu, R.3    Gaynor, R.4
  • 28
    • 0024594466 scopus 로고
    • Mutational analysis of the conserved basic domain of human immunodeficiency virus Tat protein
    • Hauber, J., M. H. Malim, and B. R. Cullen. 1989. Mutational analysis of the conserved basic domain of human immunodeficiency virus Tat protein. J. Virol. 63:1181-1187.
    • (1989) J. Virol. , vol.63 , pp. 1181-1187
    • Hauber, J.1    Malim, M.H.2    Cullen, B.R.3
  • 29
    • 0023239517 scopus 로고
    • Functional inactivation of genes by dominant negative mutations
    • Herskowitz, I. 1987. Functional inactivation of genes by dominant negative mutations. Nature (London) 329:219-222.
    • (1987) Nature (London) , vol.329 , pp. 219-222
    • Herskowitz, I.1
  • 30
    • 0024556150 scopus 로고
    • Engineering hybrid genes without the use of restriction enzymes: Gene splicing by overlap extension
    • Horton, R. M., H. D. Hunt, S. N. Ho, J. K. Pullen, and L. R. Pease. 1989. Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension. Gene 77:61-68.
    • (1989) Gene , vol.77 , pp. 61-68
    • Horton, R.M.1    Hunt, H.D.2    Ho, S.N.3    Pullen, J.K.4    Pease, L.R.5
  • 31
    • 10244221783 scopus 로고    scopus 로고
    • Unpublished data
    • Ivanoff, L. Unpublished data.
    • Ivanoff, L.1
  • 32
    • 0027360471 scopus 로고
    • Effects of integration and replication on transcription of the HIV-1 long terminal repeat
    • Jeang, K.-T., B. Berkhout, and B. Dropulic. 1993. Effects of integration and replication on transcription of the HIV-1 long terminal repeat. J. Biol. Chem. 268:24940-24949.
    • (1993) J. Biol. Chem. , vol.268 , pp. 24940-24949
    • Jeang, K.-T.1    Berkhout, B.2    Dropulic, B.3
  • 33
    • 0027260617 scopus 로고
    • In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and SpI transcription factor
    • Jeang, K.-T., R. Chun, N. H. Lin, A. Gatignol, C. G. Glabe, and H. Fan. 1993. In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and SpI transcription factor. J. Virol. 67:6224-6233.
    • (1993) J. Virol. , vol.67 , pp. 6224-6233
    • Jeang, K.-T.1    Chun, R.2    Lin, N.H.3    Gatignol, A.4    Glabe, C.G.5    Fan, H.6
  • 34
    • 0023798827 scopus 로고
    • Transcriptional activation of homologous viral long terminal repeats by the human immunodeficiency virus type I or the human T-cell leukemia virus type I tat proteins occurs in the absence of de novo protein synthesis
    • Jeang, K. T., P. R. Shank, and A. Kumar. 1988. Transcriptional activation of homologous viral long terminal repeats by the human immunodeficiency virus type I or the human T-cell leukemia virus type I tat proteins occurs in the absence of de novo protein synthesis. Proc. Natl. Acad. Sci. USA 85: 8291-8295.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8291-8295
    • Jeang, K.T.1    Shank, P.R.2    Kumar, A.3
  • 35
    • 0028290825 scopus 로고
    • Control of RNA initiation and elongation at the HIV-1 promoter
    • Jones, K. A., and B. M. Peterlin. 1994. Control of RNA initiation and elongation at the HIV-1 promoter. Annu. Rev. Biochem. 63:717-743.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 717-743
    • Jones, K.A.1    Peterlin, B.M.2
  • 36
    • 0026729568 scopus 로고
    • Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral Tat protein and cellular transcription factor SpI
    • Kamine, J., and G. Chinnadurai. 1992. Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral Tat protein and cellular transcription factor SpI. J. Virol. 66:3932-3936.
    • (1992) J. Virol. , vol.66 , pp. 3932-3936
    • Kamine, J.1    Chinnadurai, G.2
  • 37
    • 0027377289 scopus 로고
    • Activation of a heterologous promoter by human immunodeficiency virus type 1 requires Sp1 and is distinct from the mode of activation by acidic transcriptional activators
    • Kamine, J., T. Subramanian, and G. Chinnadurai. 1993. Activation of a heterologous promoter by human immunodeficiency virus type 1 requires Sp1 and is distinct from the mode of activation by acidic transcriptional activators. J. Virol. 67:6828-6834.
    • (1993) J. Virol. , vol.67 , pp. 6828-6834
    • Kamine, J.1    Subramanian, T.2    Chinnadurai, G.3
  • 38
    • 0023513563 scopus 로고
    • Antitermination of transcription within the long terminal repeat of HIV-1 by tat gene product
    • Kao, S. Y., A. F. Calman, P. A. Luciw, and B. M. Peterlin. 1987. Antitermination of transcription within the long terminal repeat of HIV-1 by tat gene product. Nature (London) 330:489-493.
    • (1987) Nature (London) , vol.330 , pp. 489-493
    • Kao, S.Y.1    Calman, A.F.2    Luciw, P.A.3    Peterlin, B.M.4
  • 40
    • 0026568822 scopus 로고
    • HIV-1 tat acts as a processivity factor in vitro in conjunction with cellular elongation factors
    • Kato, H., H. Sumimoto, P. Pognonec, C.-H. Chen, C. A. Rosen, and R. G. Roeder. 1992. HIV-1 tat acts as a processivity factor in vitro in conjunction with cellular elongation factors. Genes Dev. 6:655-666.
    • (1992) Genes Dev. , vol.6 , pp. 655-666
    • Kato, H.1    Sumimoto, H.2    Pognonec, P.3    Chen, C.-H.4    Rosen, C.A.5    Roeder, R.G.6
  • 41
    • 10244236017 scopus 로고    scopus 로고
    • Personal communication
    • Khalili, K. Personal communication.
    • Khalili, K.1
  • 42
    • 0024591269 scopus 로고
    • Multiple functional domains of tat. the trans-activator of HIV-1, defined by mutational analysis
    • Kuppuswamy, M., T. Subramanian, A. Srinivasan, and G. Chinnadurai. 1989. Multiple functional domains of tat. the trans-activator of HIV-1, defined by mutational analysis. Nucleic Acids Res. 17:3551-3561.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 3551-3561
    • Kuppuswamy, M.1    Subramanian, T.2    Srinivasan, A.3    Chinnadurai, G.4
  • 43
    • 0027721156 scopus 로고
    • The development and testing of retroviral vectors expressing transdominant mutants of HIV proteins to confer anti-HIV-1 resistance
    • Liem, S. E., A. Ramezani, X. Li, and S. Joshi. 1993. The development and testing of retroviral vectors expressing transdominant mutants of HIV proteins to confer anti-HIV-1 resistance. Hum. Gene Ther. 4:625-634.
    • (1993) Hum. Gene Ther. , vol.4 , pp. 625-634
    • Liem, S.E.1    Ramezani, A.2    Li, X.3    Joshi, S.4
  • 44
    • 0028938547 scopus 로고
    • An autoregulated dual-function antitat gene for human immunodeficiency virus type 1 gene therapy
    • Lisziewicz, J., D. Sun, B. Trapnell, M. Thomson, H.-K. Chang, B. Ensoli, and B. Peng. 1995. An autoregulated dual-function antitat gene for human immunodeficiency virus type 1 gene therapy. J. Virol. 69:206-212.
    • (1995) J. Virol. , vol.69 , pp. 206-212
    • Lisziewicz, J.1    Sun, D.2    Trapnell, B.3    Thomson, M.4    Chang, H.-K.5    Ensoli, B.6    Peng, B.7
  • 45
    • 0026685175 scopus 로고
    • Specific NF-κB suhunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription
    • Liu, J., N. D. Perkins, R. M. Schmid, and G. J. Nabel. 1992. Specific NF-κB suhunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription. J. Virol. 66:3883-3887.
    • (1992) J. Virol. , vol.66 , pp. 3883-3887
    • Liu, J.1    Perkins, N.D.2    Schmid, R.M.3    Nabel, G.J.4
  • 46
    • 0028103611 scopus 로고
    • Regulated expression of a dominant negative form of Rev improves resistance to H1V replication in T cells
    • Liu, J., C. Woffendin, Z. Yang, and G. J. Nabel. 1994. Regulated expression of a dominant negative form of Rev improves resistance to H1V replication in T cells. Gene Ther. 1:32-37.
    • (1994) Gene Ther. , vol.1 , pp. 32-37
    • Liu, J.1    Woffendin, C.2    Yang, Z.3    Nabel, G.J.4
  • 47
    • 0027460061 scopus 로고
    • The human immunodeficiency type 1 long terminal repeat specifies two different transcription complexes, only one of which is regulated by tat
    • Lu, X., T. M. Welsh, and B. M. Peterlin. 1993. The human immunodeficiency type 1 long terminal repeat specifies two different transcription complexes, only one of which is regulated by tat. J. Virol. 67:1752-1760.
    • (1993) J. Virol. , vol.67 , pp. 1752-1760
    • Lu, X.1    Welsh, T.M.2    Peterlin, B.M.3
  • 48
    • 0028944804 scopus 로고
    • In vitro interaction of the human immunodeficiency virus type 1 Tat transactivator and the general transcription factor TFIIB with the cellular protein TAP
    • Lu, Y., P. M. Loewenstein, Z. Zhang, and M. Green. 1995. In vitro interaction of the human immunodeficiency virus type 1 Tat transactivator and the general transcription factor TFIIB with the cellular protein TAP. J. Virol. 69:3017-3023.
    • (1995) J. Virol. , vol.69 , pp. 3017-3023
    • Lu, Y.1    Loewenstein, P.M.2    Zhang, Z.3    Green, M.4
  • 49
    • 0027234623 scopus 로고
    • Functional analysis of interactions between tat and the trans-activation response element of human immunodeficiency virus type 1 in cells
    • Luo, Y., S. J. Madore, T. G. Parslow, B. R. Cullen, and B. M. Peterlin. 1993. Functional analysis of interactions between tat and the trans-activation response element of human immunodeficiency virus type 1 in cells. J. Virol. 67:5617-5622.
    • (1993) J. Virol. , vol.67 , pp. 5617-5622
    • Luo, Y.1    Madore, S.J.2    Parslow, T.G.3    Cullen, B.R.4    Peterlin, B.M.5
  • 50
    • 0027192905 scopus 로고
    • Juxtaposition between activation and basic domains of human immunodeficiency virus type 1 tat is required for optimal interactions between tat and TAR
    • Luo, Y., and B. M. Peterlin. 1993. Juxtaposition between activation and basic domains of human immunodeficiency virus type 1 tat is required for optimal interactions between tat and TAR. J. Virol. 67:3441-3445.
    • (1993) J. Virol. , vol.67 , pp. 3441-3445
    • Luo, Y.1    Peterlin, B.M.2
  • 51
    • 0027310927 scopus 로고
    • Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 tat function
    • Madore, S. J., and B. R. Cullen. 1993. Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 tat function. J. Virol. 67:3703-3711.
    • (1993) J. Virol. , vol.67 , pp. 3703-3711
    • Madore, S.J.1    Cullen, B.R.2
  • 52
    • 0028889028 scopus 로고
    • Functional similarities between HIV-1 Tat and DNA sequence-specific transcriptional activators
    • Madore, S. J., and B. R. Cullen. 1995. Functional similarities between HIV-1 Tat and DNA sequence-specific transcriptional activators. Virology 206: 1150-1154.
    • (1995) Virology , vol.206 , pp. 1150-1154
    • Madore, S.J.1    Cullen, B.R.2
  • 53
    • 0026064723 scopus 로고
    • HIV-1 tat protein promotes formation of more-processive elongation complexes
    • Marciniak, R. A., and P. A. Sharp. 1990. HIV-1 tat protein promotes formation of more-processive elongation complexes. EMBO J. 10:4189-4196.
    • (1990) EMBO J. , vol.10 , pp. 4189-4196
    • Marciniak, R.A.1    Sharp, P.A.2
  • 54
    • 0026211594 scopus 로고
    • Trans-dominant Tat mutants with alterations in the basic domain inhibit HIV-1 gene expression
    • Modesti, N., J. Garcia, C. Debouck, M. Peterlin, and R. Gaynor. 1991. Trans-dominant Tat mutants with alterations in the basic domain inhibit HIV-1 gene expression. New Biol. 3:759-768.
    • (1991) New Biol. , vol.3 , pp. 759-768
    • Modesti, N.1    Garcia, J.2    Debouck, C.3    Peterlin, M.4    Gaynor, R.5
  • 56
    • 10244257079 scopus 로고    scopus 로고
    • Unpublished data
    • Orsini, M. Unpublished data.
    • Orsini, M.1
  • 57
    • 0025324686 scopus 로고
    • A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat
    • Pearson, L., J. Garcia, F. Wu, N. Modesti, J. Nelson, and R. Gaynor. 1990. A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat. Proc. Natl. Acad. Sci. USA. 87:5079-5083.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5079-5083
    • Pearson, L.1    Garcia, J.2    Wu, F.3    Modesti, N.4    Nelson, J.5    Gaynor, R.6
  • 58
    • 0023683667 scopus 로고
    • How eukaryotic transcriptional activators work
    • Ptashne, M. 1988. How eukaryotic transcriptional activators work. Nature (London) 335:683-689.
    • (1988) Nature (London) , vol.335 , pp. 683-689
    • Ptashne, M.1
  • 59
    • 0024753237 scopus 로고
    • The acidic amino-terminal region of the HIV-1 Tat protein constitutes an essential activating domain
    • Rappaport, J., S. J. Lee, K. Khalili, and S. F. Wong. 1989. The acidic amino-terminal region of the HIV-1 Tat protein constitutes an essential activating domain. New Biol. 1:101-110.
    • (1989) New Biol. , vol.1 , pp. 101-110
    • Rappaport, J.1    Lee, S.J.2    Khalili, K.3    Wong, S.F.4
  • 60
    • 0026723116 scopus 로고
    • Functional analysis of the N-terminal domain of Tat protein of the human immunodeficiency virus type 1
    • Reddy, M. V., M. Desai, J. Jeyapaul, D. D. Prasad, T. Seshamma, D. Palmeri, and S. A. Khan. 1992. Functional analysis of the N-terminal domain of Tat protein of the human immunodeficiency virus type 1. Oncogene 7:1743-1748.
    • (1992) Oncogene , vol.7 , pp. 1743-1748
    • Reddy, M.V.1    Desai, M.2    Jeyapaul, J.3    Prasad, D.D.4    Seshamma, T.5    Palmeri, D.6    Khan, S.A.7
  • 61
    • 0025240436 scopus 로고
    • Mutational analysis of the conserved cysteine-rich region of the human immunodeficiency virus type I Tat protein
    • Rice, A. P., and F. Carlotti. 1990. Mutational analysis of the conserved cysteine-rich region of the human immunodeficiency virus type I Tat protein. J. Virol. 64:1864-1868.
    • (1990) J. Virol. , vol.64 , pp. 1864-1868
    • Rice, A.P.1    Carlotti, F.2
  • 62
    • 0026094392 scopus 로고
    • Tat protein of human immunodeficiency virus type 1 is a monomer when expressed in mammalian cells
    • Rice, A. P., and F. Chan. 1991. Tat protein of human immunodeficiency virus type 1 is a monomer when expressed in mammalian cells. Virology 185:451-454.
    • (1991) Virology , vol.185 , pp. 451-454
    • Rice, A.P.1    Chan, F.2
  • 63
    • 0025039584 scopus 로고
    • Trans-activation by HIV-1 tat via a heterologous RNA binding protein
    • Selby, M. J., and B. M. Peterlin. 1990. Trans-activation by HIV-1 tat via a heterologous RNA binding protein. Cell 62:769-776.
    • (1990) Cell , vol.62 , pp. 769-776
    • Selby, M.J.1    Peterlin, B.M.2
  • 64
    • 0025239390 scopus 로고
    • Effects of a highly basic region of human immunodeficiency virus Tat protein on nucleolar localization
    • Siomi, H., H. Shida, M. Maki, and M. Hatanaka. 1990. Effects of a highly basic region of human immunodeficiency virus Tat protein on nucleolar localization. J. Virol. 64:1803-1807.
    • (1990) J. Virol. , vol.64 , pp. 1803-1807
    • Siomi, H.1    Shida, H.2    Maki, M.3    Hatanaka, M.4
  • 65
    • 0025333764 scopus 로고
    • Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein
    • Southgate, C., M. L. Zapp, and M. R. Green. 1990. Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein. Nature (London) 345:640-642.
    • (1990) Nature (London) , vol.345 , pp. 640-642
    • Southgate, C.1    Zapp, M.L.2    Green, M.R.3
  • 66
    • 0026309016 scopus 로고
    • The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: Implications for Tat function
    • Southgate, C. D., and M. R. Green. 1991. The HIV-1 Tat protein activates transcription from an upstream DNA-binding site: implications for Tat function. Genes Dev. 5:2496-2507.
    • (1991) Genes Dev. , vol.5 , pp. 2496-2507
    • Southgate, C.D.1    Green, M.R.2
  • 67
    • 0025895051 scopus 로고
    • Heterologous basic domain substitutions in the HIV-1 Tat protein reveal an argininerich motif required for transactivation
    • Subramanian, T., R. Govindarajan, and G. Chinnadurai. 1991. Heterologous basic domain substitutions in the HIV-1 Tat protein reveal an argininerich motif required for transactivation. EMBO J. 10:2311-2318.
    • (1991) EMBO J. , vol.10 , pp. 2311-2318
    • Subramanian, T.1    Govindarajan, R.2    Chinnadurai, G.3
  • 68
    • 0025266929 scopus 로고
    • Functional substitution of the basic domain of the HIV-1 trans-activator, tat, with the basic domain of the functionally heterologous rev
    • Subramanian, T., M. Kuppuswamy, L. Venkatesh, A. Srinivasan, and G. Cinnadurai. 1990. Functional substitution of the basic domain of the HIV-1 trans-activator, tat, with the basic domain of the functionally heterologous rev. Virology 176:178-183.
    • (1990) Virology , vol.176 , pp. 178-183
    • Subramanian, T.1    Kuppuswamy, M.2    Venkatesh, L.3    Srinivasan, A.4    Cinnadurai, G.5
  • 69
    • 0025837282 scopus 로고
    • Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation
    • Sullenger, B. A., H. F. Gallardo, G. E. lingers, and E. Gilboa. 1991. Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation. J. Virol. 65:6811-6816.
    • (1991) J. Virol. , vol.65 , pp. 6811-6816
    • Sullenger, B.A.1    Gallardo, H.F.2    Lingers, G.E.3    Gilboa, E.4
  • 70
    • 0028940546 scopus 로고
    • Transcriptional trans activation by human immunodeficiency type 1 Tat requires specific coactivators that are not basal factors
    • Suñé, C., and M. A. García-Blanco. 1995. Transcriptional trans activation by human immunodeficiency type 1 Tat requires specific coactivators that are not basal factors. J. Virol. 69:3098-3107.
    • (1995) J. Virol. , vol.69 , pp. 3098-3107
    • Suñé, C.1    García-Blanco, M.A.2
  • 71
    • 0026731480 scopus 로고
    • TAR-independent transactivation by Tat in cells derived from the CNS: A novel mechanism of HIV-1 gene regulation
    • Taylor, J. P., R. Pomerantz, O. Bagasra, M. Chowdhury, J. Rappaport, K. Khalili, and S. Amini. 1992. TAR-independent transactivation by Tat in cells derived from the CNS: a novel mechanism of HIV-1 gene regulation. EMBO J. 11:3395-3403.
    • (1992) EMBO J. , vol.11 , pp. 3395-3403
    • Taylor, J.P.1    Pomerantz, R.2    Bagasra, O.3    Chowdhury, M.4    Rappaport, J.5    Khalili, K.6    Amini, S.7
  • 72
    • 0028283271 scopus 로고
    • Central nervous system-derived cells express a κB-binding activity that enhances human immunodeficiency virus type 1 transcription in vitro and facilitates TAR-independent transactivation by Tat
    • Taylor, J. P., R. J. Pomerantz, G. V. Raj, F. Kashanchl, J. N. Brady, S. Amini, and K. Khalili. 1994. Central nervous system-derived cells express a κB-binding activity that enhances human immunodeficiency virus type 1 transcription in vitro and facilitates TAR-independent transactivation by Tat. J. Virol. 68:3971-3981.
    • (1994) J. Virol. , vol.68 , pp. 3971-3981
    • Taylor, J.P.1    Pomerantz, R.J.2    Raj, G.V.3    Kashanchl, F.4    Brady, J.N.5    Amini, S.6    Khalili, K.7
  • 73
    • 0025187536 scopus 로고
    • Does the human immunodeficiency virus tat trans-activator contain a discrete activation domain?
    • Tiley, L. S., P. H. Brown, and B. R. Cullen. 1990. Does the human immunodeficiency virus tat trans-activator contain a discrete activation domain? Virology 178:560-567.
    • (1990) Virology , vol.178 , pp. 560-567
    • Tiley, L.S.1    Brown, P.H.2    Cullen, B.R.3
  • 74
    • 0026490317 scopus 로고
    • The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence
    • Tiley, L. S., S. J. Madore, M. H. Malim, and B. R. Cullen. 1992. The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence. Genes Dev. 6:2077-2087.
    • (1992) Genes Dev. , vol.6 , pp. 2077-2087
    • Tiley, L.S.1    Madore, S.J.2    Malim, M.H.3    Cullen, B.R.4
  • 75
    • 0024024137 scopus 로고
    • Functional dissection of VP16, the transactivator of herpes simplex virus immediate early gene expression
    • Triezenberg, S. J., R. C. Kingsbury, and S. L. McKnight. 1988. Functional dissection of VP16, the transactivator of herpes simplex virus immediate early gene expression. Genes Dev. 2:718-729.
    • (1988) Genes Dev. , vol.2 , pp. 718-729
    • Triezenberg, S.J.1    Kingsbury, R.C.2    McKnight, S.L.3
  • 77
    • 0025740889 scopus 로고
    • trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain hinds a transcription factor
    • Webster, L. C., and R. P. Ricciardi. 1991. trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain hinds a transcription factor. Mol. Cell. Biol. 11:4287-4296.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4287-4296
    • Webster, L.C.1    Ricciardi, R.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.