Evidence for an in vivo superantigenic activity in human immunodeficiency virus-infected individuals

Blood

Volumn 88, Issue 6, 1996, Pages 2151-2161

  Garcia, Sylvie ^b   Dadaglio, Gilles ^b   Cilote, Vanina ^b   Chenal, Henry ^b   Bondurand, Alain ^b   Gougeon, Marie Lise ^a  

^a INSTITUT PASTEUR   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; BLOOD; CLONAL ANERGY; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPH NODE CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0029794755     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.6.2151.bloodjournal8862151     Document Type: Article

References (52)

1. Herman A, Kappler JW, Marrack P, Pullen AM: Superantigens: Mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol 9:745, 1991
2. Ohmen JD, Barnes PF, Grisso CL, Bloom BR, Modlin RL: Evidence for a superantigen in human tuberculosis. Immunity 1:35, 1994
3. Abe J, Takeda T, Watanabe Y, Nakao H, Kobayashi N, Leung DY, Kohsaka T: Evidence for superantigen production by Yersinia pseudotuberculosis. J Immunol 151:4183, 1993
4. Bowness P, Moss PA, Tranter H, Bell JI, McMichael AJ: Clostridium perfringens enterotoxin is a superantigen reactive with human T cell receptors V beta 6.9 and V beta 22. J Exp Med 176:893, 1992
5. Denkers EY, Caspar P, Sher A: Toxoplasma gondii possesses a superantigen activity that selectively expands murine T cell receptor V beta 5-bearing CD8+ lymphocytes. J Exp Med 180:985, 1994
6. Lafon M, Lafage M, Martinez-Arends A, Ramirez R, Vuillier F, Charron D, Lotteau V, Scott-Algara D: Evidence for a viral superantigen in humans. Nature 358:507, 1992
7. Dobrescu D, Ursea B, Pope M, Asch AS, Posnett DN: Enhanced HIV-1 replication in Vβ12 T cells due to human Cytomegalovirus in monocytes. Evidence for a putative Herpesvirus superantigen. Cell 82:753, 1995
8. Hugin AW, Vacchio MS, Morse H III: A virus-encoded "superantigen" in a retrovirus-induced immunodeficiency syndrome of mice. Science 252:424, 1991
9. Acha-Orbea H, Shakhov AN, Scarpellino L, Kolb E, Muller V, Vessaz-Shaw A, Fuchs R, Blochlinger K, Rollini P, Billotte J, Sarafidou M, MacDonald HR, Diggelmann H: Clonal deletion of V beta 14-bearing T cells in mice transgenic for mammary tumour virus. Nature 350:207, 1991
10. Janeway C: Immune recognition. MIs: Makes a little sense. Nature 349:459, 1991
11. Haase AT, Jenkins MK, Peng H, Urdahl K: nef-naf nexus? Immunodeficiency 2:130, 1992
12. Imberti L, Sottini A, Bettinardi A, Puoti M, Primi D: Selective depletion in HIV infection of T cells that bear specific T cell receptor V beta sequences. Science 254:860, 1991
13. Dalgleish A, Wilson S, Gompels M, Ludlam C, Gazzard B, Coates A, Habeshaw J: T-cell receptor variable gene products and early HIV-I infection. Lancet 339:824, 1992
14. Boldt-Houle DM, Rinaldo CRJ, Ehrlich GD: Random depletion of T cells that bear specific T cell receptor Vβ sequences in AIDS patients. J Leukoc Biol 54:486, 1993
15. Boyer V, Smith LR, Ferre F, Pezzoli P, Trauger RJ, Jensen FC, Carlo DJ: T cell receptor V beta repertoire in HIV-infection individuals: Lack of evidence for selective V beta deletion. Clin Exp Immunol 92:437, 1993
16. Hodara VL, Jeddi-Tehrani M, Grunewald J, Andersson R, Scarlatti G, Esin S, Holmberg V, Libonatti O, Wigzell H: HIV infection leads to differential expression of T-cell receptor V beta genes in CD4+ and CDS+ T cells. AIDS 7:633, 1993
17. Postnett DN, Kabak S, Hodtsev AS, Glodberg EA, Asch A: TCR-Vβ subsets are not preferentially deleted in AIDS. AIDS 7:625, 1993
18. Bahadoran P, Rieux-Laucat F, Le Deist F, Blanche S, Fischer A, de Villartay JP: Lack of selective V beta deletion in peripheral CD4+ T cells of human immunodeficiency virus-infected infants. Eur J Immunol 23:2041, 1993
19. Rebai N, Pantaleo G, Demarest JF, Ciurli C, Soudeyns H, Adelsberger JW, Vaccarezza M, Walker RE, Sekaly RP, Fauci AS: Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: Evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins. Proc Natl Acad Sci USA 91:1529, 1994
20. Nisini R, Aiuti A, Matricardi PM, Fattorossi A, Ferlini C, Biselli R, Mezzaroma I, Pinter E, D'Amelio R: Lack of evidence for a superantigen in lymphocytes from HIV-discordant monozygotic twins. AIDS 8:443, 1994
21. Soudeyns H, Routy JP, Sekaly RP: Comparative analysis of the T cell receptor V beta repertoire in various lymphoid tissues from HIV-infected patients: Evidence for an HIV-associated superantigen. Leukemia 8:S95, 1994
22. Gulwani-Akolkar B, Posnett DN, Janson CH, Grunewald J, Wigzell H, Akolkar P, Gregersen PK, Silver J: T cell receptor V-segment frequencies in peripheral blood T cells correlate with human leukocyte antigen type. J Exp Med 174:1139, 1991
23. Rammensee HG, Kroschewski R, Frangoulis B: Clonal anergy induced in mature V beta 6+ T lymphocytes on immunizing Mls-lb mice with Mls-la expressing cells. Nature 339:541, 1989
24. Rellahan BL, Jones LA, Kruisbeek AM, Fry AM, Matis LA: In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B. J Exp Med 172:1091, 1990
25. Kawabe Y, Ochi A: Selective anergy of V beta 8+, CD4+ T cells in Staphylococcus enterotoxin B-primed mice. J Exp Med 172:1065, 1990
26. Lee WT, Vitetta ES: Memory T cells are anergic to the superantigen staphylococcal enterotoxin B. J Exp Med 176:575, 1992
27. Dadaglio G, Garcia S, Montagnier L, Gougeon ML: Selective anergy of V beta 8+ T cells in human immunodeficiency virus-infected individuals. J Exp Med 179:413, 1994
28. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
29. Genevee C, Diu A, Nierat J, Caignart A, Dietrich PY, Ferradini L, Roman-Roman S, Triebel F, Hercend T: An experimentally validated panel of subfamily-specific oligonucleotide primers (Val-w29/Vβ1-w24) for the study of human T cell receptor variable V gene segment usage by PCR. Eur J Immunol 22:1261, 1992
30. Cochet M, Pannetier C, Regnault A, Darche S, Leclerc C, Kourilsky P: Molecular detection and in vivo analysis of the specific T cell response to a protein antigen. Eur J Immunol 22:2639, 1992
31. Buyse I, Decorte R, Baens M, Cuppens H, Semana G, Emonds MP, Marynen P, Cassiman JJ: Rapid DNA typing of class II HLA antigens using the polymerase chain reaction and reverse dot blot hybridization. Tissue Antigens 41:1, 1993
32. Abe J, Forrester J, Nakahara T, Lafferty J, Kotzin B, Leung D: Selective stimulation of human T cells with streptococcal erythrogenic toxins A and B. J Immunol 146:3747, 1991
33. Fleischer B, Gerardi-Schahn R, Metzroth B, Carrel S, Gerlach D, Köhler W: An evolutionary conserved mechanism of T cell activation by microbial toxins. Evidence for different affinities of T cell receptor-toxin interaction. J Immunol 146:11, 1991
34. Pannetier C, Even J, Kourilsky P: T-cell repertoire diversity and clonal expansions in normal and clinical samples. Immunol Today 176:176, 1995
35. Even J, Lim A, Puisieux L, Ferradini L, Dietrich PY, Toubert A, Hercend T, Triebel F, Pannetier C, Kourilsky P: T-cell repertoire in healthy and diseased human tissues analysed by T-cell receptor β-chain CDR3 size determination: Evidence for clonal expansions in tumours and inflammatory diseases. Res Immunol 146:65, 1995
36. Cole BC, Atkin CL: The Mycoplasma arthritidis T-cell mitogen, MAM: A model superantigen. Immunol Today 12:271, 1991
37. Grau O, Slizewicz B, Tuppin P, Launay V, Bourgeois E, Sagot N, Moynier M, Lafeuillade A, Bachelez H, Clauvel JP, Blanchard A, Bahraoui E, Montagnier L: Association of Mycoplasma penetrans with human immunodeficiency virus infection. J Infect Dis 172:672, 1995
38. Embretson J, Zupancic M, Ribas JL, Burke A, Racz P, Tenner-Racz K, Haase AT: Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature 362:359, 1993
39. Pantaleo G, Graziosi C, Demarest JF, Butini L, Montroni M, Fox CH, Orenstein JM, Kotler DP, Fauci AS: HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature 362:355, 1993
40. Cottrez F, Auriault C, Capron A, Groux H: Analysis of the V beta specificity of superantigen activation with a rapid and sensitive method using RT PCR and an automatic DNA analyser. J Immunol Methods 172:85, 1994
41. Wen R, Blackman MA, Woodland DL: Variable influence of MHC polymorphism on the recognition of bacterial superantigens by T cells. J Immunol 155:1884, 1995
42. Held W, Waanders GA, MacDonald HR, Acha-Orbea H: MHC class II hierarchy of superantigen presentation predicts efficiency of infection with mouse mammary tumor virus. Int Immunol 6:1403, 1994
43. Mann DL, Carrington M, O'Donnell M, Miller T, Goedert J: HLA phenotype is a factor in determining rate of disease progression and outcome in HIV-1 -infected individuals. AIDS Res Hum Retroviruses 8:1345, 1992
44. Donald JA, Rudman K, Cooper DW, Baumgart KW, Garsia RJ, Gatenby PA, Rickard KA: Progression of HIV-related disease is associated with HLA DQ and DR alleles defined by restriction fragment length polymorphisms. Tissue Antigens 39:241, 1992
45. Fabio G, Smeraldi RS, Gringeri A, Marchini M, Bonara P, Mannucci PM: Susceptibility to HIV infection and AIDS in Italian haemophiliacs is HLA associated. Br J Haematol 75:531, 1990
46. Scorza Smeraldi R, Fabio G, Lazzarin A, Eisera NB, Moroni M, Zanussi C: HLA-associated susceptibility to acquired immunodeficiency syndrome in Italian patients with human-immunodeficiency-virus infection. Lancet 2:1187, 1986
47. Klein MR, Keet IP, D'Amaro J, Bende RJ, Hekman A, Mesman B, Koot M, de Waal LP, Coutinho RA, Miedema F: Associations between HLA frequencies and pathogenic features of human immunodeficiency virus type 1 infection in seroconverters from the Amsterdam cohort of homosexual men. J Infect Dis 169:1244, 1994
48. Papasteriades C, Kaloterakis A, Filiotou A, Economidou J, Nicolis G, Trichopoulos D, Stratigos J: Histocompatibility antigens HLA-A, -B, -DR in Greek patients with Kaposi's sarcoma. Tissue Antigens 24:313, 1984
49. Contu L, Cerimele D, Pintus A, Cottoni F, La Nasa G: HLA and Kaposi's sarcoma in Sardinia. Tissue Antigens 23:240, 1984
50. Laurence J, Hodtsev AS, Posnett DN: Superantigen implicated in dependence of HIV-1 replication in T cells on TCR V beta expression. Nature 358:255, 1992
51. Dobrescu D, Kabak S, Mehta K, Suh CH, Asch A, Cameron DU, Hodtsev AS, Postnett DN: Human immunodeficiency virus 1 reservoir in CD4+ T cells is restricted to certain Vβ subsets. Proc Natl Acad Sci USA 92:5563, 1995
52. Blauvelt A, Clerici M, Lucey DR, Steinberg SM, Yarchoan R, Walker R, Shearer GM, Katz SI: Functional studies of epidermal Langerhans cells and blood monocytes in HIV-infected persons. J Immunol 154:3506, 1995