Effects of centrally administered prostaglandin EP receptor agonists on febrile and adrenocortical responses in the prepubertal pig

Brain Research Bulletin

Volumn 41, Issue 2, 1996, Pages 97-103

  Parrott, R F ^a   Vellucci, S V ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

Cortisol; Fever; Porcine brain; Prolactin; Prostanoid receptors

Indexed keywords

HYDROCORTISONE; PROLACTIN; PROSTAGLANDIN E2; PROSTANOID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORE TEMPERATURE; CORTICOTROPIN RELEASE; DOSE RESPONSE; FEVER; HORMONE RESPONSE; HYDROCORTISONE BLOOD LEVEL; HYPERTHERMIA; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PREPUBERTY; PRIORITY JOURNAL; SWINE; SYNAPTOSOME; THERMOREGULATION;

EID: 0029794719     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(96)00156-6     Document Type: Article

References (22)

1. 1. Coceani, F.; Bishai, I.; Engelberts, D.; House, R. V.; Adamson, S. L. Response of newborn and adult sheep to pyrogens: Relation between fever and brain eicosanoid changes. Brain Res. 700:191-204; 1995.
2. 2. Coleman, R. A.; Smith, W. L.; Narumiya, S. VIII. International union of pharmacology classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes. Pharmacol. Rev. 46:206-229; 1994.
3. 3. Gollman, H. M.; Rudy, T. A. Comparative pyrogenic potency of endogenous prostanoids and of prostanoid-mimetics injected into the anterior hypothalamic/preoptic region of the cat. Brain Res. 449:281-293; 1988.
4. 2 administered intravenously crosses the blood-brain barrier and induces hyperthermia as a central action. Ann. NY Acad. Sci. 559:451-452; 1989.
5. 2α receptors in brain synaptosomes of newborn than of adult pigs. J. Pharmacol. Exp. Ther. 267:1292-1297; 1993.
6. 2α receptor density in brain microvessels of pigs. Br. J. Pharmacol. 112:59-64; 1994.
7. 2 sensitivity of the organosum vasculosum lamina terminalis region and preoptic area in rat brain slices. J. Physiol. (Lond.) 454:197-212; 1992.
8. 2 is involved in physiological sleep-wake regulation in rats. Proc. Natl. Acad. Sci. USA 86:5666-5669; 1989.
9. 9. Morimoto, A.; Murakami, N.; Nakamori, T.; Watanabe, T. Multiple control of fever production in the central nervous system of rabbits. J. Physiol. (Lond.) 397:269-280; 1988.
10. 2-induced hyperthermia in rats. Am. J. Physiol. 267:R289-R294; 1994.
11. 11. Parrott, R. F. Central effects of CCK ligands in pigs making operant responses for food. Pharmacol. Biochem. Behav. 49:463-449; 1994.
12. 12. Parrott, R. F.; Goode, J. A. Effects of intracerebroventricular corticotropin-releasing hormone and intravenous morphine on cortisol, prolactin and growth hormone secretion in sheep. Domest. Anim. Endocrinol. 9:141-149; 1992.
13. 13. Parrott, R. F.; Lloyd, D. M. Restraint, but not frustration, induces prostaglandin-mediated hyperthermia in pigs. Physiol. Behav. 57:1051-1055; 1995.
14. 14. Parrott, R. F.; Vellucci, S. V.; Forsling, M. L.; Goode, J. A. Hyperthermic and endocrine effects of intravenous prostaglandin administration in the pig. Domest. Anim. Endocrinol. 12:197-205; 1995.
15. 15. Parrott, R. F.; Vellucci, S. V.; Goode, J. A.; Lloyd, D. M.; Forsling, M. L. Cyclo-oxygenase mediation of endotoxin-induced fever, anterior and posterior pituitary hormone release, and hypothalamic c-Fos expression in the prepubertal pig. Exp. Physiol. 80:663-674; 1995.
16. 16. Shibata, M.; Leffler, C. W.; Busija, D. W. Recombinant human interleukin 1α dilates pial arterioles and increases cerebrospinal fluid prostanoids in piglets. Am. J. Physiol. 259:L1486-L1491; 1990.
17. 1 induces hyperthermia in macaque species. Can. J. Physiol. Pharmacol. 71:416-424; 1992.
18. 18. Simpson, C. W.; Ruwe, W. D.; Myers, R. D. Prostaglandin and hypothalamic neurotransmitter receptors involved in hyperthermia: A critical evaluation. Neurosci. Biobehav. Rev. 18:1-20; 1994.
19. 3 in the mouse nervous system. Neuroscience 62:919-928; 1994.
20. 2. Brain. Res. 645:165-169; 1994.
21. 21. Williams, J. W.; Rudy, T. A.; Yaksh, T. L.; Viswanathan, C. T. An extensive exploration of the rat brain for sites mediating prostaglandin-induced hyperthermia. Brain Res. 120:251-262; 1977.
22. 2 binding protein from porcine cerebral cortex. J. Neurochem. 46:125-132; 1986.