Transforming growth factor-α promotes tumor markers secretion from human ovarian cancers in vitro

Cancer

Volumn 78, Issue 5, 1996, Pages 1049-1054

  Kurachi, Hirohisa ^a   Adachi, Hiroshi ^a   Morishige, Ken Ichirou ^a   Adachi, Kazushige ^a   Takeda, Takashi ^a   Homma, Hiroaki ^a   Yamamoto, Toshiya ^a   Miyake, Akira ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

CA125; ovarian cancer; serous cystadenocarcinoma; tissue polypeptide antigen (TPA); transforming growth factor a epidermal growth factor (TGF EGF) receptor autocrine mechanism

Indexed keywords

CA 125 ANTIGEN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; IODINE 125; TISSUE POLYPEPTIDE ANTIGEN; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR MARKER;

ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYSTADENOCARCINOMA; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; OVARY CANCER; PRIORITY JOURNAL; RECEPTOR BINDING;

BINDING SITES; CA-125 ANTIGEN; CYSTADENOCARCINOMA; FEMALE; HUMANS; NEOPLASM STAGING; OVARIAN NEOPLASMS; PEPTIDES; RECEPTOR, EPIDERMAL GROWTH FACTOR; TISSUE POLYPEPTIDE ANTIGEN; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 0029794478     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19960901)78:5<1049::AID-CNCR15>3.0.CO;2-2     Document Type: Article

References (22)

1. Derynck R, Goeddel DV, Ullrich A, Gutterman JU, Williams RD, Bringman TS, et al. Synthesis of messenger RNAs for transforming growth factor α and β and the epidermal growth factor receptor by human tumors. Cancer Res 1987;47:707-12.
2. Valverius EM, Bates SE, Stampfer MR, Clark R, McCormic F, Salomon DS, et al. Transforming growth factor α production and epidermal growth factor receptor expression in normal and oncogens transformed human mammary epithelial cells. Mol Endocrinol 1989;3:203-14.
3. Morishige K, Kurachi H, Amemiya K, Adachi H, Inoue M, Miyake A, et al. Involvement of transforming growth factor α/epidermal growth factor receptor autocrine mechanism in an ovarian cancer cell line in vitro. Cancer Res 1991; 51:5951-5.
4. Kurachi H, Morishige K, Amemiya K, Adachi H, Hirota K, Miyake A, et al. Importance of transforming growth factor α/epidermal growth factor receptor autocrine growth mechanism in an ovarian cancer cell line in vivo. Cancer Res 1991;51:5956-9.
5. Morishige K, Kurachi H, Amemiya K, Fujita Y, Yamamoto T, Miyake A, et al. Evidence for the involvement of transforming growth factor α and epidermal growth factor receptor autocrine growth mechanism in primary human ovarian cancers in vitro. Cancer Res 1991;51:5322-8.
6. Bauknecht T, Kiechle M, Bauer G, Siebers JW. Characterization of growth factors in human ovarian carcinomas. Cancer Res 1986;46:2614-8.
7. Bjorklund B, Bjorklund V. Antigenicity of pooled human malignant and normal tissues by cyto-immunological technique: presence of an insoluble, heatlabile tumor antigen. Int Arch Allergy Immunol 1957;10:153-84.
8. Bast RC, Feeney M, Lazarus H, Nadler LM, Colvin RB, Knapp RC. Reactivity of a monoclonal antibody with human ovarian carcinoma. J Clin Invest 1981;68:1331-7.
9. Bast RE, Klug TL, St. John E. A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer. N Engl J Med 1983;309:883-7.
10. Cuatrecasas P. Affinity chromatography and purification of the insulin receptor of liver cell membranes. Proc Natl Acad Sci USA 1972;69:1277-80.
11. Chen CF, Kurachi H, Fujita Y, Terakawa N, Miyake A, Tanizawa O. Changes in epidermal growth factor receptor and its messenger ribonucleic acid levels in human placenta and isolated trophoblast cells during pregnancy. J Clin Endocrinol Metab 1988;67:1171-7.
12. Imai S, Kiyozuka Y, Maeda H, Noda T, Howard LH. Establishment and characterization of a human ovarian serous cystadenocarcinoma cell line that produces the tumor markers CA 125 and tissue polypeptide antigen. Oncology 1991; 47:177-84.
13. Kurachi H, Morishige K, Adachi H, Adachi K, Tasaka K, Sawada M, et al. Implantation and growth of epidermal growth factor (EGF) receptor expressing human ovarian cancer xenografts in nude mice is dependent on EGF. Cancer 1994; 74:2984-90.
14. Kiyozuka Y, Noda T, Adachi S, Adachi S, Akada S, Ichijo M. Study of the mechanism of tumor marker CA-125 in serum. Acta Obstet Gynecol Jpn 1989;41:1951-8.
15. Knauf S, Urbach GI. Ovarian tumor-associated antigen. In: Herberman RB, editor. Compendium of assays for immunodiagnosis of human cancer. Amsterdam: Elsevir/North-Holland Biomedical Press, 1979:537-9.
16. Kabawat SE, Bast RC, Bhan AK, Welch WR, Knapp RC, Colvin RB. Immunopathologic characterization of a monoclonal antibody that recognizes common surface antigens of human ovarian tumors of serous, endometrioid and clear cell types. Am J Clin Pathol 1983;79:98-104.
17. Kabawat SE, Bast RC, Bhan AK, Welch WR, Knapp RC, Colvin RB. Tissue distribution of a coelomic epithelium related antigen recognized by the monoclonal antibody OC125. Int J Gynecol Pathol 1983;2:275-83.
18. Klug TL, Bast RC, Niloff JM, Knapp RC, Zurawski VR Jr. Monoclonal antibody immunoradiometric assay for an antigenic determinant (CA125) associated with human epithelial ovarian carcinomas. Cancer Res 1984;44:1048-53.
19. Niloff JM, Knapp RC, Schaetzl E, Reynolds C, Bast RC. CA125 antigen levels in obstetric and gynecologic patients. Obstet Gynecol 1984;64:703-7.
20. Imai T, Kurachi H, Adachi K, Adachi H, Yoshimoto Y, Homma H, et al. Changes in epidermal growth factor receptor and the levels of its ligands during menstrual cycle in human endometrium. Biol Reprod 1995;52:928-38.
21. Nelson KG, Takahashi T, Bossert NL, Walmer DK, MacLachlan JA. Epidermal growth factor replaces estrogen in the stimulation of the female genital-tract growth and differentiation. Proc Natl Acad Sci USA 1991;88:21-5.
22. Nelson KG, Takahashi T, Lee DC, Bossert NL, Ross K, Eitzman BE, et al. Transforming growth factor-α is a potential mediator of estrogen action in the mouse uterus. Endocrinology 1992;131:1657-64.