메뉴 건너뛰기




Volumn 21, Issue 7, 1996, Pages 831-841

The response of motoneurons to neurotrophins

Author keywords

brain derived neurotrophic factor; motoneuron; motoneuron survival; neurotrophin 3, neurotrophin 4; Spinal cord

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN 4;

EID: 0029794239     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02532307     Document Type: Review
Times cited : (73)

References (125)
  • 1
    • 70449239593 scopus 로고
    • Regression versus peripheral control of differentiation in motor hyperplasia
    • Hamburger, V. 1958. Regression versus peripheral control of differentiation in motor hyperplasia. Am. J. Anat. 102:365-410.
    • (1958) Am. J. Anat. , vol.102 , pp. 365-410
    • Hamburger, V.1
  • 2
    • 0016637156 scopus 로고
    • Cell death in the development of the lateral column of the chick embryo
    • Hamburger, V. 1975. Cell death in the development of the lateral column of the chick embryo. J. Comp. Neurol. 160:535-546.
    • (1975) J. Comp. Neurol. , vol.160 , pp. 535-546
    • Hamburger, V.1
  • 3
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim, R. W. 1991. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14:453-501.
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 4
    • 0021522805 scopus 로고
    • Motoneurons purified by cell sorting respond to two distinct activities in myotube-conditioned medium
    • Calof, A. L., and Reichardt, L. F. 1984. Motoneurons purified by cell sorting respond to two distinct activities in myotube-conditioned medium. Dev. Biol. 106:194-210.
    • (1984) Dev. Biol. , vol.106 , pp. 194-210
    • Calof, A.L.1    Reichardt, L.F.2
  • 5
    • 0023003776 scopus 로고
    • Muscle-derived factors that support survival and promote fiber outgrowth from embryonic chick spinal motor neurons in culture
    • Dohrmann, U., Edgar, D., Sendtner, M. and Thoenen, H. 1986. Muscle-derived factors that support survival and promote fiber outgrowth from embryonic chick spinal motor neurons in culture. Dev. Biol. 118:209-221.
    • (1986) Dev. Biol. , vol.118 , pp. 209-221
    • Dohrmann, U.1    Edgar, D.2    Sendtner, M.3    Thoenen, H.4
  • 6
    • 0022471166 scopus 로고
    • Motoneuron survival factor requirements during development: The change from immature astrocyte dependence to myotubve dependence
    • Eagleson, K. L., and Bennett, M. R. 1986. Motoneuron survival factor requirements during development: The change from immature astrocyte dependence to myotubve dependence. Dev. Brain Res. 28:161-172.
    • (1986) Dev. Brain Res. , vol.28 , pp. 161-172
    • Eagleson, K.L.1    Bennett, M.R.2
  • 7
    • 0022243855 scopus 로고
    • Cell survival characteristics and choline acetyl transferase activity in motoneuron-enriched cultures from chick embryo spinal cord
    • Flanigan, T. P., Dickson, J. G., and Walsh, F. S. 1985. Cell survival characteristics and choline acetyl transferase activity in motoneuron-enriched cultures from chick embryo spinal cord. J. Neurochem. 45:1323-1326.
    • (1985) J. Neurochem. , vol.45 , pp. 1323-1326
    • Flanigan, T.P.1    Dickson, J.G.2    Walsh, F.S.3
  • 8
    • 0024464486 scopus 로고
    • Characterisation of two factors enhancing choline acetyltransferase activity in cultures of purified rat motoneurons
    • Martinou, J. C., Le Van Thai, A., Cassar, G., Roubinet, F., and Weber, M. J. 1989. Characterisation of two factors enhancing choline acetyltransferase activity in cultures of purified rat motoneurons. J. Neurosci. 9:3645-3656.
    • (1989) J. Neurosci. , vol.9 , pp. 3645-3656
    • Martinou, J.C.1    Le Van Thai, A.2    Cassar, G.3    Roubinet, F.4    Weber, M.J.5
  • 9
    • 0023029157 scopus 로고
    • Isolation of embryonic chick motoneurons and their survival in vitro
    • O'Brien, R. J., and Fischbach, G. D. 1986. Isolation of embryonic chick motoneurons and their survival in vitro. J. Neurosci. 6:3265-3274.
    • (1986) J. Neurosci. , vol.6 , pp. 3265-3274
    • O'Brien, R.J.1    Fischbach, G.D.2
  • 10
    • 0019794038 scopus 로고
    • Separation of cell types from embryonic chicken and rat spinal cord: Characterization of motoneuron-enriched fractions
    • Schnaar, R. L., and Schaffner, A. E. 1981. Separation of cell types from embryonic chicken and rat spinal cord: Characterization of motoneuron-enriched fractions. J. Neurosci. 1:204-214.
    • (1981) J. Neurosci. , vol.1 , pp. 204-214
    • Schnaar, R.L.1    Schaffner, A.E.2
  • 11
    • 0022378661 scopus 로고
    • Trophic effects of skeletal muscle extracts on ventral spinal cord neurons in vitro: Separation of a protein with morphologic activity from proteins with cholinergic activity
    • R.G.
    • Smith, R. G., McManaman, J., and Appel, S. H. 1985. Trophic effects of skeletal muscle extracts on ventral spinal cord neurons in vitro: separation of a protein with morphologic activity from proteins with cholinergic activity. J. Cell Biol. 101:1608-1621. R. G.
    • (1985) J. Cell Biol. , vol.101 , pp. 1608-1621
    • Smith, R.G.1    McManaman, J.2    Appel, S.H.3
  • 12
    • 0026550179 scopus 로고
    • Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro
    • Martinou, J. C., Martinou, I., and Kato, A. 1992. Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro. Neuron 8:737-744.
    • (1992) Neuron , vol.8 , pp. 737-744
    • Martinou, J.C.1    Martinou, I.2    Kato, A.3
  • 13
    • 0026010959 scopus 로고
    • Survival in vitro of motoneurons identified or purified by novel antibody-based methods is selectively enhanced by muscle-derived factors
    • Bloch-Gallego, E., Huchet, M., El M'Hamdi, H., Xie, F. -K., Tanaka, H., and Henderson, C. E. 1991. Survival in vitro of motoneurons identified or purified by novel antibody-based methods is selectively enhanced by muscle-derived factors. Development 11:221-232.
    • (1991) Development , vol.11 , pp. 221-232
    • Bloch-Gallego, E.1    Huchet, M.2    El M'Hamdi, H.3    Xie, F.K.4    Tanaka, H.5    Henderson, C.E.6
  • 14
    • 0026630523 scopus 로고
    • Purification of embryonic rat motoneurons by panning on a monoclonal antibody to the low-affinity NGF receptor
    • Camu, W., and Henderson, C. E. 1992. Purification of embryonic rat motoneurons by panning on a monoclonal antibody to the low-affinity NGF receptor. J. Neurosci. Methods 44:59-70.
    • (1992) J. Neurosci. Methods , vol.44 , pp. 59-70
    • Camu, W.1    Henderson, C.E.2
  • 15
    • 0025514410 scopus 로고
    • Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines
    • Arakawa, Y., Sendtner, M., and Thoenen, H. 1990. Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines. J. Neurosci. 10:3507-3515.
    • (1990) J. Neurosci. , vol.10 , pp. 3507-3515
    • Arakawa, Y.1    Sendtner, M.2    Thoenen, H.3
  • 16
    • 0023392238 scopus 로고
    • Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons
    • Unsicker, K., Reichert-Preibsch, H., Schmidt, R., Pettmann, B., Labourdette, G., and Sensenbrenner, M. 1987. Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons. PNAS 84:5459-5463.
    • (1987) PNAS , vol.84 , pp. 5459-5463
    • Unsicker, K.1    Reichert-Preibsch, H.2    Schmidt, R.3    Pettmann, B.4    Labourdette, G.5    Sensenbrenner, M.6
  • 17
    • 0027131764 scopus 로고
    • Members of several gene families influence survival of rat motoneurons in vitro and in vivo
    • Hughes, R. A., Sendtner, M., and Thoenen, H. 1993. Members of several gene families influence survival of rat motoneurons in vitro and in vivo. J. Neurosci. Res. 36(6):663-671.
    • (1993) J. Neurosci. Res. , vol.36 , Issue.6 , pp. 663-671
    • Hughes, R.A.1    Sendtner, M.2    Thoenen, H.3
  • 19
    • 0025983810 scopus 로고
    • Regional distribution, developmental changes and cellular localization of CNTF-mRNA and protein in the rat brain
    • Stöckli, K. A., Lillien, L. E., Näher-Noe, M., Breitfeld, G., Hughes, R. A., Thoenen, H., and Sendtner, M. 1991. Regional distribution, developmental changes and cellular localization of CNTF-mRNA and protein in the rat brain. J. Cell Biol. 115:447-459.
    • (1991) J. Cell Biol. , vol.115 , pp. 447-459
    • Stöckli, K.A.1    Lillien, L.E.2    Näher-Noe, M.3    Breitfeld, G.4    Hughes, R.A.5    Thoenen, H.6    Sendtner, M.7
  • 20
    • 0027403260 scopus 로고
    • The alpha component of the cntf receptor is required for signaling and defines potential cntf targets in the adult and during development
    • Ip, N. Y., McClain, J., Barrezueta, N. X., Aldrich, T. H., Pan, L., Li, Y. P., Wiegand, S. J., Friedman, B., Davis, S., and Yancopoulos, G. D. 1993. The alpha component of the cntf receptor is required for signaling and defines potential cntf targets in the adult and during development. Neuron 10:89-102.
    • (1993) Neuron , vol.10 , pp. 89-102
    • Ip, N.Y.1    McClain, J.2    Barrezueta, N.X.3    Aldrich, T.H.4    Pan, L.5    Li, Y.P.6    Wiegand, S.J.7    Friedman, B.8    Davis, S.9    Yancopoulos, G.D.10
  • 21
    • 0027756168 scopus 로고
    • Trophic support of motoneurons: Physiological, pathophysiological, and therapeutic implications
    • Thoenen, H., Hughes, R. A., and Sendtner, M. 1993. Trophic support of motoneurons: Physiological, pathophysiological, and therapeutic implications. Exp. Neurol. 124:47-55.
    • (1993) Exp. Neurol. , vol.124 , pp. 47-55
    • Thoenen, H.1    Hughes, R.A.2    Sendtner, M.3
  • 23
    • 0025317838 scopus 로고
    • Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family
    • Hohn, A., Leibrock, J., Bailey, K., and Barde, Y.-A. 1990. Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family. Nature 344:339-341.
    • (1990) Nature , vol.344 , pp. 339-341
    • Hohn, A.1    Leibrock, J.2    Bailey, K.3    Barde, Y.-A.4
  • 26
    • 0025312351 scopus 로고
    • Cloning and expression of a cDNA encoding a novel human neurotrophic factor
    • Kaisho, Y., Yoshimura, K., and Nakahama, K. 1990. Cloning and expression of a cDNA encoding a novel human neurotrophic factor. FEBS Lett. 266:187-191.
    • (1990) FEBS Lett. , vol.266 , pp. 187-191
    • Kaisho, Y.1    Yoshimura, K.2    Nakahama, K.3
  • 27
    • 0025907893 scopus 로고
    • Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary
    • Hallböök, F., Ibáñez, C. F., and Persson, H. 1991. Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary. Neuron 6:845-858.
    • (1991) Neuron , vol.6 , pp. 845-858
    • Hallböök, F.1    Ibáñez, C.F.2    Persson, H.3
  • 29
    • 0013067786 scopus 로고
    • The nerve growth factor: Thirty-five years later
    • Levi-Montalcini, R. 1987. The nerve growth factor: thirty-five years later. EMBO J. 6:1145-1154.
    • (1987) EMBO J. , vol.6 , pp. 1145-1154
    • Levi-Montalcini, R.1
  • 30
    • 0024677597 scopus 로고
    • Trophic factors and neuronal survival
    • Barde, Y.-A. 1989. Trophic factors and neuronal survival. Neuron 2:1525-1534.
    • (1989) Neuron , vol.2 , pp. 1525-1534
    • Barde, Y.-A.1
  • 31
    • 0026766860 scopus 로고
    • The nerve growth factor family of receptors
    • Meakin, S. O. and Shooter, E. M. 1992. The nerve growth factor family of receptors. TINS 15:323-331.
    • (1992) TINS , vol.15 , pp. 323-331
    • Meakin, S.O.1    Shooter, E.M.2
  • 32
    • 0026730310 scopus 로고
    • Neurotrophin receptors: A window into neuronal differentiation
    • Chao, M. V. 1992. Neurotrophin receptors: A window into neuronal differentiation. Neuron 9:583-593.
    • (1992) Neuron , vol.9 , pp. 583-593
    • Chao, M.V.1
  • 33
    • 0018367557 scopus 로고
    • Nerve growth factor (NGF) in the rat CNS: Absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra
    • Schwab, M. E., Otten, U., Agid, Y. and Thoenen, H. 1979. Nerve growth factor (NGF) in the rat CNS: absence of specific retrograde axonal transport and tyrosine hydroxylase induction in locus coeruleus and substantia nigra. Brain Res. 168:473-483.
    • (1979) Brain Res. , vol.168 , pp. 473-483
    • Schwab, M.E.1    Otten, U.2    Agid, Y.3    Thoenen, H.4
  • 34
    • 0019967109 scopus 로고
    • Cell death of motoneurons in the chick embryo spinal cord VI Reduction of naturally occurring cell death in the thoracolumbar column of Terni by nerve growth factor
    • Oppenheim, R. W., Maderdrut, J. L., and Wells, D. J. 1982. Cell death of motoneurons in the chick embryo spinal cord VI Reduction of naturally occurring cell death in the thoracolumbar column of Terni by nerve growth factor. J. Comp. Neurol. 210: 174-189.
    • (1982) J. Comp. Neurol. , vol.210 , pp. 174-189
    • Oppenheim, R.W.1    Maderdrut, J.L.2    Wells, D.J.3
  • 35
    • 0010537251 scopus 로고
    • Differentiating effects of murine nerve growth factor in the peripheral and central nervous systems of Xenopus laevis tadpoles
    • Levi-Montalcini, R., and Aloe, L. 1985. Differentiating effects of murine nerve growth factor in the peripheral and central nervous systems of Xenopus laevis tadpoles. PNAS 82:7111-7115.
    • (1985) PNAS , vol.82 , pp. 7111-7115
    • Levi-Montalcini, R.1    Aloe, L.2
  • 36
    • 0022036753 scopus 로고
    • The spatial and temporal pattern of beta NGF receptor expression in the developing chick embryo
    • Raivich, G., Zimmermann, A., and Sutter, A. 1985. The spatial and temporal pattern of beta NGF receptor expression in the developing chick embryo. EMBO J. 4:637-644.
    • (1985) EMBO J. , vol.4 , pp. 637-644
    • Raivich, G.1    Zimmermann, A.2    Sutter, A.3
  • 37
    • 0023942523 scopus 로고
    • Retrograde transport of NGF by early chick embryo spinal cord motoneurons
    • Wayne, D. B., and Heaton, M. B. 1988. Retrograde transport of NGF by early chick embryo spinal cord motoneurons. Dev. Biol. 127:220-223.
    • (1988) Dev. Biol. , vol.127 , pp. 220-223
    • Wayne, D.B.1    Heaton, M.B.2
  • 38
    • 0018390672 scopus 로고
    • Retrograde transport of nerve growth factor in chicken embryo
    • Brunso-Bechtold, J. K., and Hamburger, V. 1979. Retrograde transport of nerve growth factor in chicken embryo. PNAS 76: 1494-1496.
    • (1979) PNAS , vol.76 , pp. 1494-1496
    • Brunso-Bechtold, J.K.1    Hamburger, V.2
  • 39
    • 0024020704 scopus 로고
    • Retrograde transport of nerve growth factor (NGF) in motoneurons of developing rats: Assessment of potential neurotrophic effects
    • Yan, Q., Snider, W. D., Pinzone, J. J., and Johnson, E. M., Jr., 1988. Retrograde transport of nerve growth factor (NGF) in motoneurons of developing rats: assessment of potential neurotrophic effects. Neuron 1:335-343.
    • (1988) Neuron , vol.1 , pp. 335-343
    • Yan, Q.1    Snider, W.D.2    Pinzone, J.J.3    Johnson Jr., E.M.4
  • 40
    • 0016438595 scopus 로고
    • Retrograde axonal transport of nerve growth factor: Specificity and biological importance
    • Stoeckel, K., and H. Thoenen. 1975. Retrograde axonal transport of nerve growth factor: specificity and biological importance. Brain Res. 85:337-341.
    • (1975) Brain Res. , vol.85 , pp. 337-341
    • Stoeckel, K.1    Thoenen, H.2
  • 41
    • 0021152619 scopus 로고
    • A monoclonal antibody modulates the interaction of nerve growth factor with PC12 cells
    • Chandler, C. E., Parsons, L. M., Hosang, M., and Shooter, E. M. 1984. A monoclonal antibody modulates the interaction of nerve growth factor with PC12 cells. J. Biol. Chem. 259:6882-6889.
    • (1984) J. Biol. Chem. , vol.259 , pp. 6882-6889
    • Chandler, C.E.1    Parsons, L.M.2    Hosang, M.3    Shooter, E.M.4
  • 43
    • 0023133256 scopus 로고
    • Gene transfer and molecular cloning of the rat nerve growth factor receptor: A new class of receptors
    • Radeke, M. J., Misko, T. P., Hsu, C., Herzenberg, L. A., and Shooter, E. M. 1987. Gene transfer and molecular cloning of the rat nerve growth factor receptor: a new class of receptors. Nature (London) 325:593-597.
    • (1987) Nature (London) , vol.325 , pp. 593-597
    • Radeke, M.J.1    Misko, T.P.2    Hsu, C.3    Herzenberg, L.A.4    Shooter, E.M.5
  • 44
    • 0023687398 scopus 로고
    • An immunohistochemical study of the nerve growth factor receptor in developing rats
    • Yan, Q. and Johnson, E. M., Jr. 1988. An immunohistochemical study of the nerve growth factor receptor in developing rats. J. Neurosci. 8:3481-3498.
    • (1988) J. Neurosci. , vol.8 , pp. 3481-3498
    • Yan, Q.1    Johnson Jr., E.M.2
  • 45
    • 0024145347 scopus 로고
    • Developmental and regional expression of β-nerve growth factor receptor mRNA in the chick and rat
    • Ernfors, P., Hallböök, F., Ebendal, T., Shooter, E. M., Radeke, M. J., Misko, T. P., and Persson, H. 1988. Developmental and regional expression of β-nerve growth factor receptor mRNA in the chick and rat. Neuron 1:983-996.
    • (1988) Neuron , vol.1 , pp. 983-996
    • Ernfors, P.1    Hallböök, F.2    Ebendal, T.3    Shooter, E.M.4    Radeke, M.J.5    Misko, T.P.6    Persson, H.7
  • 46
    • 0025323817 scopus 로고
    • Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of the neural crest origin in the mouse
    • Martin-Zanca, D., Barbacid, M., and Parada, L. F. 1990. Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of the neural crest origin in the mouse. Genes&Development 4:683-694.
    • (1990) Genes&Development , vol.4 , pp. 683-694
    • Martin-Zanca, D.1    Barbacid, M.2    Parada, L.F.3
  • 48
    • 0026784969 scopus 로고
    • Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: Responses to injury and infusion of NGF
    • Verge, V. M. K., Merlio, J.-P., Grondin, J., Ernfors, P., Persson, H., Riopelle, R. J., Hökfelt, T., and Richardson, P. M. 1992. Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: Responses to injury and infusion of NGF. J. Neurosci. 12:4011-4022.
    • (1992) J. Neurosci. , vol.12 , pp. 4011-4022
    • Verge, V.M.K.1    Merlio, J.-P.2    Grondin, J.3    Ernfors, P.4    Persson, H.5    Riopelle, R.J.6    Hökfelt, T.7    Richardson, P.M.8
  • 49
    • 0027459315 scopus 로고
    • Role and expression of neurotrophins and the trk family of tyrosine kinase receptors in neural growth and rescue after injury
    • Persson, U., and Ibanez, C. F. 1993. Role and expression of neurotrophins and the trk family of tyrosine kinase receptors in neural growth and rescue after injury. Current Opinion in Neurology and Neurosurgery 6:11-18.
    • (1993) Current Opinion in Neurology and Neurosurgery , vol.6 , pp. 11-18
    • Persson, U.1    Ibanez, C.F.2
  • 50
    • 0025754790 scopus 로고
    • Nerve growth factor receptor immunostaining in the spinal cord and peripheral nerves in amyotrophic lateral sclerosis
    • Berl.
    • Kerkhoff, H., Jennekens, F. G. I., Troost, D., and Veldman, H. 1991. Nerve growth factor receptor immunostaining in the spinal cord and peripheral nerves in amyotrophic lateral sclerosis. Acta Neuropathol.(Berl.) 81:649-656.
    • (1991) Acta Neuropathol. , vol.81 , pp. 649-656
    • Kerkhoff, H.1    Jennekens, F.G.I.2    Troost, D.3    Veldman, H.4
  • 51
    • 0026723840 scopus 로고
    • No reexpression of high-affinity nerve growth-factor binding-sites in spinal motor neurons in amyotrophic-lateral-sclerosis
    • Aquilonius, S. M., Askmark, H., Ebendal, T., and Gillberg, P. G. 1992. No reexpression of high-affinity nerve growth-factor binding-sites in spinal motor neurons in amyotrophic-lateral-sclerosis. Europ. Neurol. 32:216-218.
    • (1992) Europ. Neurol. , vol.32 , pp. 216-218
    • Aquilonius, S.M.1    Askmark, H.2    Ebendal, T.3    Gillberg, P.G.4
  • 53
    • 0024679252 scopus 로고
    • Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons
    • Ernfors, P., Henschen, A., Olson, L., and Persson, H. 1989. Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons. Neuron 2:1605-1613.
    • (1989) Neuron , vol.2 , pp. 1605-1613
    • Ernfors, P.1    Henschen, A.2    Olson, L.3    Persson, H.4
  • 54
    • 0022633995 scopus 로고
    • The absence of significant postnatal motoneuron death in the brachial and lumbar spinal cord of the rat
    • Oppenheim, R. W. 1986. The absence of significant postnatal motoneuron death in the brachial and lumbar spinal cord of the rat. J. Comp. Neurol. 246:281-286.
    • (1986) J. Comp. Neurol. , vol.246 , pp. 281-286
    • Oppenheim, R.W.1
  • 55
    • 0025354045 scopus 로고
    • Re-expression of Nerve-Growth Factor Receptor after Axonal Injury Recapitulates a Developmental Event in Motor Neurons: Differential Regulation when Regeneration is Allowed or Prevented
    • Wood, S. J., Pritchard, J., and Sofroniew, M. V. 1990. Re-expression of Nerve-Growth Factor Receptor after Axonal Injury Recapitulates a Developmental Event in Motor Neurons: Differential Regulation when Regeneration is Allowed or Prevented. Eur. J. Neurosci. 2:650-657.
    • (1990) Eur. J. Neurosci. , vol.2 , pp. 650-657
    • Wood, S.J.1    Pritchard, J.2    Sofroniew, M.V.3
  • 56
    • 0025761833 scopus 로고
    • Axotomy induces nerve growth factor receptor immunoreactivity in spinal motor neurons
    • Koliatsos, V. E., Crawford, T. O., and Price, D. L. 1991. Axotomy induces nerve growth factor receptor immunoreactivity in spinal motor neurons. Brain Res. 549:297-304.
    • (1991) Brain Res. , vol.549 , pp. 297-304
    • Koliatsos, V.E.1    Crawford, T.O.2    Price, D.L.3
  • 57
    • 0026028989 scopus 로고
    • A novel group of nerve growth factor receptor-immunoreactive neurons in the ventral horn of the lumbar spinal cord
    • Koliatsos, V. E., Shelton, D. L., Mobley, W. C., and Price, D. L. 1991. A novel group of nerve growth factor receptor-immunoreactive neurons in the ventral horn of the lumbar spinal cord. Brain Res. 541:121-128.
    • (1991) Brain Res. , vol.541 , pp. 121-128
    • Koliatsos, V.E.1    Shelton, D.L.2    Mobley, W.C.3    Price, D.L.4
  • 58
    • 0025320134 scopus 로고
    • The response of cultured trigeminal and spinal cord motoneurons to nerve growth factor
    • Wayne, D. B., and Heaton, M. B. 1990. The response of cultured trigeminal and spinal cord motoneurons to nerve growth factor. Dev. Biol. 138:473-483.
    • (1990) Dev. Biol. , vol.138 , pp. 473-483
    • Wayne, D.B.1    Heaton, M.B.2
  • 59
    • 0020594573 scopus 로고
    • An effect of nerve growth factor on parasympathetic neurite outgrowth
    • Collins, F., and Dawson, A. 1983. An effect of nerve growth factor on parasympathetic neurite outgrowth. PNAS 80:2091-2094.
    • (1983) PNAS , vol.80 , pp. 2091-2094
    • Collins, F.1    Dawson, A.2
  • 60
    • 0022460234 scopus 로고
    • Effects of nerve growth factor on the survival and synaptic function of 1a sensory neurons axotomized in neonatal rats
    • Miyata, Y., Kashihara, Y., Homma, S., and Kuno, M. 1986. Effects of nerve growth factor on the survival and synaptic function of 1a sensory neurons axotomized in neonatal rats. J. Neurosci. 6:2021-2018.
    • (1986) J. Neurosci. , vol.6 , pp. 2021-12018
    • Miyata, Y.1    Kashihara, Y.2    Homma, S.3    Kuno, M.4
  • 61
    • 0027070473 scopus 로고
    • Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
    • Sendtner, M., Holtmann, B., Kolbeck, R., Thoenen, H., and Barde, Y.-A. 1992. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 360:757-758.
    • (1992) Nature , vol.360 , pp. 757-758
    • Sendtner, M.1    Holtmann, B.2    Kolbeck, R.3    Thoenen, H.4    Barde, Y.-A.5
  • 62
    • 0023275887 scopus 로고
    • Nerve growth factor protects adult sensory neurons from cell death and atrophy caused by nerve injury
    • Rich, K. M., Luszcynski, J. R., Osborne, P. A., and Johnson, E. M. 1987. Nerve growth factor protects adult sensory neurons from cell death and atrophy caused by nerve injury. J. Neurocytol. 16:261-268.
    • (1987) J. Neurocytol. , vol.16 , pp. 261-268
    • Rich, K.M.1    Luszcynski, J.R.2    Osborne, P.A.3    Johnson, E.M.4
  • 63
    • 0023256354 scopus 로고
    • Changes of nerve growth factor synthesis in non-neuronal cells in responses to sciatic nerve transection
    • Heumann, R., Korsching, S., Bandtlow, C., and Thoenen, H. 1987. Changes of nerve growth factor synthesis in non-neuronal cells in responses to sciatic nerve transection. J. Cell Biol. 104: 1623-1631.
    • (1987) J. Cell Biol. , vol.104 , pp. 1623-1631
    • Heumann, R.1    Korsching, S.2    Bandtlow, C.3    Thoenen, H.4
  • 64
    • 0023461564 scopus 로고
    • Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: Role of macrophages
    • Heumann, R., Lindholm, D., Bandtlow, C., Meyer, M. Radeke, M. J., Misko, T. P., Shooter, E. M., and Thoenen, H. 1987. Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: Role of macrophages. PNAS 84:8735-8739.
    • (1987) PNAS , vol.84 , pp. 8735-8739
    • Heumann, R.1    Lindholm, D.2    Bandtlow, C.3    Meyer, M.4    Radeke, M.J.5    Misko, T.P.6    Shooter, E.M.7    Thoenen, H.8
  • 65
    • 0026768108 scopus 로고
    • Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: Different mechanisms are responsible for the regulation of BDNF and NGF mRNA
    • Meyer, M., Matsuoka, I., Wetmore, C., Olson, L., and Thoenen, H. 1992. Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: Different mechanisms are responsible for the regulation of BDNF and NGF mRNA. J. Cell Biol. 119:45-54.
    • (1992) J. Cell Biol. , vol.119 , pp. 45-54
    • Meyer, M.1    Matsuoka, I.2    Wetmore, C.3    Olson, L.4    Thoenen, H.5
  • 66
    • 0027481752 scopus 로고
    • Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo
    • Koliatsos, V. E., Clatterbuck, R. E., Winslow, J. W., Cayouette, M. U., and Price, D. L. 1993. Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo. Neuron 10:359-367.
    • (1993) Neuron , vol.10 , pp. 359-367
    • Koliatsos, V.E.1    Clatterbuck, R.E.2    Winslow, J.W.3    Cayouette, M.U.4    Price, D.L.5
  • 67
    • 0025790316 scopus 로고
    • Developmentally regulated expression of NDNF/NT-3 mRNA in rat spinal cord motoneurons and expression of BDNF mRNA in embryonic dorsal root ganglion
    • Ernfors, P., and Persson, H. 1991. Developmentally regulated expression of NDNF/NT-3 mRNA in rat spinal cord motoneurons and expression of BDNF mRNA in embryonic dorsal root ganglion. Europ. J. Neurosci. 3:953-961.
    • (1991) Europ. J. Neurosci. , vol.3 , pp. 953-961
    • Ernfors, P.1    Persson, H.2
  • 68
    • 0025325548 scopus 로고
    • Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy
    • Sendtner, M., Kreutzberg, G. W., and Thoenen, U. 1990. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 345:440-441.
    • (1990) Nature , vol.345 , pp. 440-441
    • Sendtner, M.1    Kreutzberg, G.W.2    Thoenen, U.3
  • 69
    • 0027067035 scopus 로고
    • Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
    • Yan, Q., Elliott, J., and Snider, W. D. 1992. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature 360:753-755.
    • (1992) Nature , vol.360 , pp. 753-755
    • Yan, Q.1    Elliott, J.2    Snider, W.D.3
  • 70
    • 0026703471 scopus 로고
    • The trkB tyrosine protein kinase is a receptor for neurotrophin-4
    • Klein, R., Lamballe, F., Bryant, S., and Barbacid, M. 1992. The trkB tyrosine protein kinase is a receptor for neurotrophin-4. Neuron 8:947-956.
    • (1992) Neuron , vol.8 , pp. 947-956
    • Klein, R.1    Lamballe, F.2    Bryant, S.3    Barbacid, M.4
  • 71
    • 0027161953 scopus 로고
    • trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues
    • Tessarollo, L., Tsoulfas, P., Martin-Zanca, D. Gilbert, D. J., Jenkins, N. A., Copeland, N. G., and Parada, L. F. 1993. trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues. Development 118:463-475.
    • (1993) Development , vol.118 , pp. 463-475
    • Tessarollo, L.1    Tsoulfas, P.2    Martin-Zanca, D.3    Gilbert, D.J.4    Jenkins, N.A.5    Copeland, N.G.6    Parada, L.F.7
  • 72
  • 73
    • 0027270865 scopus 로고
    • trkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificities
    • Lamballe, F., Tapley, P., and Barbacid, M. 1993. trkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificities. EMBO J. 12:3083-3094.
    • (1993) EMBO J. , vol.12 , pp. 3083-3094
    • Lamballe, F.1    Tapley, P.2    Barbacid, M.3
  • 74
    • 0027430692 scopus 로고
    • Molecular cloning and cellular localization of trk C in the chicken embryo
    • Williams, R., Bäckström, A., Ebendal, T., and Hallböök, F. 1993. Molecular cloning and cellular localization of trk C in the chicken embryo. Dev. Brain Res. 75:235-252.
    • (1993) Dev. Brain Res. , vol.75 , pp. 235-252
    • Williams, R.1    Bäckström, A.2    Ebendal, T.3    Hallböök, F.4
  • 75
    • 0026634815 scopus 로고
    • The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons
    • Di Stefano, P. S., Friedman, B., Radziejewski, C., Alexander, C., Boland, P., Schick, C. M., Lindsay, R. M., and Wiegand, S. J. 1992. The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons. Neuron 8:983-993.
    • (1992) Neuron , vol.8 , pp. 983-993
    • Di Stefano, P.S.1    Friedman, B.2    Radziejewski, C.3    Alexander, C.4    Boland, P.5    Schick, C.M.6    Lindsay, R.M.7    Wiegand, S.J.8
  • 76
    • 0027094145 scopus 로고
    • Brain-derived neurotrophic factor resues developing avian motoneurons from cell death
    • Oppenheim, R. W., Qin-Wei, Y., Prevette, D., and Yan, Q. 1992. Brain-derived neurotrophic factor resues developing avian motoneurons from cell death. Nature 360:755-757.
    • (1992) Nature , vol.360 , pp. 755-757
    • Oppenheim, R.W.1    Qin-Wei, Y.2    Prevette, D.3    Yan, Q.4
  • 78
    • 0023855585 scopus 로고
    • Brain-derived neurotrophic factor prevents neuronal death in vivo
    • Hofer, M. M., and Barde, Y. A. 1988. Brain-derived neurotrophic factor prevents neuronal death in vivo. Nature 331:261-262.
    • (1988) Nature , vol.331 , pp. 261-262
    • Hofer, M.M.1    Barde, Y.A.2
  • 81
    • 0025896342 scopus 로고
    • TrkB mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor
    • Glass, D. J., Nye, S. H., Hantzopoulos, P., Macchi, M. J., Squinto, S. P., Goldfarb, M., and Yancopoulos, G. D. 1991. TrkB mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor. Cell 66:405-413.
    • (1991) Cell , vol.66 , pp. 405-413
    • Glass, D.J.1    Nye, S.H.2    Hantzopoulos, P.3    Macchi, M.J.4    Squinto, S.P.5    Goldfarb, M.6    Yancopoulos, G.D.7
  • 83
    • 0027528768 scopus 로고
    • Similarities and differences in the way neurotrophins interact with the trk receptors in neuronal and nonneuronal cells
    • Ip, N. Y., Stitt, T. N., Tapley, P., Klein, R., Glass, D. J., Fandl, J., Greene, L. A., Barbacid, M., and Yancopoulos, G. D. 1993. Similarities and differences in the way neurotrophins interact with the trk receptors in neuronal and nonneuronal cells. Neuron 10:137-149.
    • (1993) Neuron , vol.10 , pp. 137-149
    • Ip, N.Y.1    Stitt, T.N.2    Tapley, P.3    Klein, R.4    Glass, D.J.5    Fandl, J.6    Greene, L.A.7    Barbacid, M.8    Yancopoulos, G.D.9
  • 84
    • 0025321521 scopus 로고
    • Binding of brain-derived neurotrophic factor to the nerve growth factor receptor
    • Rodriguez-Tébar, A., Dechant, G., and Barde, Y.-A. 1990. Binding of brain-derived neurotrophic factor to the nerve growth factor receptor. Neuron 4:487-492.
    • (1990) Neuron , vol.4 , pp. 487-492
    • Rodriguez-Tébar, A.1    Dechant, G.2    Barde, Y.-A.3
  • 85
    • 0026608541 scopus 로고
    • Binding of neurotrophin-3 to its neuronal receptors and interaction with nerve growth factor and brain-derived neurotrophic factor
    • Rodriguez-Tébar, A., Dechant, G., Götz, R., and Barde, Y.-A. 1992. Binding of neurotrophin-3 to its neuronal receptors and interaction with nerve growth factor and brain-derived neurotrophic factor. EMBO J. 11:917-922.
    • (1992) EMBO J. , vol.11 , pp. 917-922
    • Rodriguez-Tébar, A.1    Dechant, G.2    Götz, R.3    Barde, Y.-A.4
  • 87
    • 0026747063 scopus 로고
    • Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral nervous system
    • Lee, K.-F., Li, E., Huber, L. J., Landis, S. C., Sharpe, A. H., Chao, M. V., and Jaenisch, R. 1992. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral nervous system. Cell 69:737-749.
    • (1992) Cell , vol.69 , pp. 737-749
    • Lee, K.-F.1    Li, E.2    Huber, L.J.3    Landis, S.C.4    Sharpe, A.H.5    Chao, M.V.6    Jaenisch, R.7
  • 88
    • 0028264964 scopus 로고
    • Positive and negative effects of neurotrophins on the isthmo-optic nucleus in chick embryos
    • Von Bartheld, C. S., Kinoshita, Y., Prevette, D., Yin, Q.-W., Oppenheim, R. W., and Bothwell, M. 1994. Positive and negative effects of neurotrophins on the isthmo-optic nucleus in chick embryos. Neuron 12:639-654.
    • (1994) Neuron , vol.12 , pp. 639-654
    • Von Bartheld, C.S.1    Kinoshita, Y.2    Prevette, D.3    Yin, Q.-W.4    Oppenheim, R.W.5    Bothwell, M.6
  • 89
    • 0026787533 scopus 로고
    • Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons
    • Schecterson, L. C., and M. Bothwell. 1992. Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons. Neuron 9:449-463.
    • (1992) Neuron , vol.9 , pp. 449-463
    • Schecterson, L.C.1    Bothwell, M.2
  • 90
    • 0026728919 scopus 로고
    • Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival
    • Wright, E. M., Vogel, K. S., and Davies, A. M. 1992. Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival. Neuron 9:139-150.
    • (1992) Neuron , vol.9 , pp. 139-150
    • Wright, E.M.1    Vogel, K.S.2    Davies, A.M.3
  • 92
    • 0025980590 scopus 로고
    • Axonal projections and synaptogenesis by supraspinal descending neurons in the spinal cord of the chick embryo
    • Shiga, T., Künzi, R., and Oppenheim, R. W. 1991. Axonal projections and synaptogenesis by supraspinal descending neurons in the spinal cord of the chick embryo. J. Comp. Neurol. 305: 83-95.
    • (1991) J. Comp. Neurol. , vol.305 , pp. 83-95
    • Shiga, T.1    Künzi, R.2    Oppenheim, R.W.3
  • 93
    • 0025119187 scopus 로고
    • NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression
    • Maisonpierre, P. C., Belluscio, L., Squinto, S., Ip, N. Y., Furth, M. E., Lindsay, R. M., and Yancopoulos, G. D. 1990. NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression. Neuron 5:501-509.
    • (1990) Neuron , vol.5 , pp. 501-509
    • Maisonpierre, P.C.1    Belluscio, L.2    Squinto, S.3    Ip, N.Y.4    Furth, M.E.5    Lindsay, R.M.6    Yancopoulos, G.D.7
  • 94
    • 0027207328 scopus 로고
    • Widespread and developmentally regulated expression of neurotrophin-4 mRNA in rat brain and peripheral tissues
    • Timmusk, T., Belluardo, N., Metsis, M., and Persson, H. 1993. Widespread and developmentally regulated expression of neurotrophin-4 mRNA in rat brain and peripheral tissues. Europ. J. Neurosci. 5:605-613.
    • (1993) Europ. J. Neurosci. , vol.5 , pp. 605-613
    • Timmusk, T.1    Belluardo, N.2    Metsis, M.3    Persson, H.4
  • 95
    • 0029116339 scopus 로고
    • Expression of neurotrophins in skeletal muscle: Quantitative comparison and significance for motoneuron survival and maintenance of function
    • Griesbeck, O., Parsadanian, A. Sh., Sendtner, M., and Thoenen, H. 1995. Expression of neurotrophins in skeletal muscle: Quantitative comparison and significance for motoneuron survival and maintenance of function. J. Neurosci. Res. 42:21-33.
    • (1995) J. Neurosci. Res. , vol.42 , pp. 21-33
    • Griesbeck, O.1    Parsadanian, A.Sh.2    Sendtner, M.3    Thoenen, H.4
  • 96
    • 0027468101 scopus 로고
    • Coexpression of messenger-mas for ngf, bdnf, and nt-3 in the cardiovascular-system of the prenatal and postnatal rat
    • Scarisbrick, I. A., Jones, E. G., and Isackson, P. J. 1993. Coexpression of messenger-mas for ngf, bdnf, and nt-3 in the cardiovascular-system of the prenatal and postnatal rat. J. Neurosci. 13:875-893.
    • (1993) J. Neurosci. , vol.13 , pp. 875-893
    • Scarisbrick, I.A.1    Jones, E.G.2    Isackson, P.J.3
  • 97
    • 0025279814 scopus 로고
    • Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain
    • Hofer, M., Pagliusi, S. R., Hohn, A., Leibrock, J., and Barde, Y.-A. 1990. Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain. EMBO J. 9:2459-2464.
    • (1990) EMBO J. , vol.9 , pp. 2459-2464
    • Hofer, M.1    Pagliusi, S.R.2    Hohn, A.3    Leibrock, J.4    Barde, Y.-A.5
  • 98
    • 0027516028 scopus 로고
    • Cellular localization of brain-derived neurotrophic factor and neurotrophin-3 mRNA in the early chicken embryo
    • Hallböök, F., Ibanez, C. F., Ebendahl, T., and Persson, H. 1993. Cellular localization of brain-derived neurotrophic factor and neurotrophin-3 mRNA in the early chicken embryo. Europ. J. Neurosci. 5:1-14.
    • (1993) Europ. J. Neurosci. , vol.5 , pp. 1-14
    • Hallböök, F.1    Ibanez, C.F.2    Ebendahl, T.3    Persson, H.4
  • 99
    • 0027360908 scopus 로고
    • Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve
    • Funakoshi, H., Frisen, J., Barbany, G., Timmusk, T., Zachrisson, O., Verge, V. M. K., and Persson, H. 1993. Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve. J. Cell. Biol. 123:455-465.
    • (1993) J. Cell. Biol. , vol.123 , pp. 455-465
    • Funakoshi, H.1    Frisen, J.2    Barbany, G.3    Timmusk, T.4    Zachrisson, O.5    Verge, V.M.K.6    Persson, H.7
  • 100
    • 0029024336 scopus 로고
    • Muscle-derived Neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons
    • Funakoshi, H., Belluasdo, N., Arenas, E., Yamamoto, Y., Casabona, A., Persson, H., and Ibanez, C. F. 1995. Muscle-derived Neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. SCIENCE 268:1495-1499.
    • (1995) SCIENCE , vol.268 , pp. 1495-1499
    • Funakoshi, H.1    Belluasdo, N.2    Arenas, E.3    Yamamoto, Y.4    Casabona, A.5    Persson, H.6    Ibanez, C.F.7
  • 101
    • 0027491104 scopus 로고
    • Targeted disruption of the trkB neurotrophin receptor results in nervous system lesions and neonatal death
    • Klein, R., Smeyne, R. J., Wurst, W., Long, L. K., Auerbach, B. A., Joyner, A. L., and Barbacid, M. 1993. Targeted disruption of the trkB neurotrophin receptor results in nervous system lesions and neonatal death. Cell 75:113-122.
    • (1993) Cell , vol.75 , pp. 113-122
    • Klein, R.1    Smeyne, R.J.2    Wurst, W.3    Long, L.K.4    Auerbach, B.A.5    Joyner, A.L.6    Barbacid, M.7
  • 102
    • 0028351190 scopus 로고
    • Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development
    • Jones, K. R., Fariñas, I., Backus, C., and Reichardt, L. F. 1994. Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 76: 989-999.
    • (1994) Cell , vol.76 , pp. 989-999
    • Jones, K.R.1    Fariñas, I.2    Backus, C.3    Reichardt, L.F.4
  • 103
    • 0028274040 scopus 로고
    • Mice lacking brain-derived neurotrophic factor develop with sensory deficits
    • Ernfors, P., Lee, K.-F., and Jaenisch, R. 1994. Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature 368:147-150.
    • (1994) Nature , vol.368 , pp. 147-150
    • Ernfors, P.1    Lee, K.-F.2    Jaenisch, R.3
  • 105
    • 0029014099 scopus 로고
    • Sensory but not motor neuron deficits in mice lacking NT4 and BDNF
    • Liu, X., Ernfors, P., Wu, H., and Jaenisch, R. 1995. Sensory but not motor neuron deficits in mice lacking NT4 and BDNF. Nature 375:238-240.
    • (1995) Nature , vol.375 , pp. 238-240
    • Liu, X.1    Ernfors, P.2    Wu, H.3    Jaenisch, R.4
  • 107
    • 0028291238 scopus 로고
    • Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents
    • Ernfors, P., Lee, K.-F., Kucera, J., and Jaenisch, R. 1994. Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell 77:503-512.
    • (1994) Cell , vol.77 , pp. 503-512
    • Ernfors, P.1    Lee, K.-F.2    Kucera, J.3    Jaenisch, R.4
  • 108
    • 0028322183 scopus 로고
    • Severe sensory and sympathetic deficits in mice lacking neurotrophin-3
    • Farinas, I., Jones, K. R., Backus, C., Wang, X.-Y., and Reichardt, L. F. 1994. Severe sensory and sympathetic deficits in mice lacking neurotrophin-3. Nature 369:658-661.
    • (1994) Nature , vol.369 , pp. 658-661
    • Farinas, I.1    Jones, K.R.2    Backus, C.3    Wang, X.-Y.4    Reichardt, L.F.5
  • 109
    • 0029128530 scopus 로고
    • Reduction in the number of spinal motor neurons in neurotrophin-3-deficient mice
    • Kucera, J., Ernfors, P., and Jaenisch, R. 1995. Reduction in the number of spinal motor neurons in neurotrophin-3-deficient mice. Neurosci. 69:312-330.
    • (1995) Neurosci. , vol.69 , pp. 312-330
    • Kucera, J.1    Ernfors, P.2    Jaenisch, R.3
  • 110
    • 0026683802 scopus 로고
    • Further studies on the distribution of CDF/LIF mRNA
    • Patterson, P. H. and Fann, M.-J. 1992. Further studies on the distribution of CDF/LIF mRNA. In Ciba Found Symposium 167. 125-140.
    • (1992) Ciba Found Symposium 167 , pp. 125-140
    • Patterson, P.H.1    Fann, M.-J.2
  • 111
    • 0026743120 scopus 로고
    • The downregulation of growth-associated proteins in motoneurons at the onset of synapse elimination is controlled by muscle activity and IGF-1
    • Caroni, P. and Becker, M. 1992. The downregulation of growth-associated proteins in motoneurons at the onset of synapse elimination is controlled by muscle activity and IGF-1. J. Neurosci. 12:3849-3861.
    • (1992) J. Neurosci. , vol.12 , pp. 3849-3861
    • Caroni, P.1    Becker, M.2
  • 112
    • 0024338750 scopus 로고
    • Basic fibroblast growth factor in the chick embryo: Immunolocalization to striated muscle cells and their precursors
    • Joseph-Silverstein, J. J., Consigli, S. A., Lyser, K. M., and Ver Fault, C. 1989. Basic fibroblast growth factor in the chick embryo: immunolocalization to striated muscle cells and their precursors. J. Cell Biol. 108:2459-2466.
    • (1989) J. Cell Biol. , vol.108 , pp. 2459-2466
    • Joseph-Silverstein, J.J.1    Consigli, S.A.2    Lyser, K.M.3    Ver Fault, C.4
  • 113
    • 0024463562 scopus 로고
    • Multiple neurotrophic factors from skeletal muscle: Demonstration of effects of basic fibroblast growth factor and comparisons with the 22-kilodalton choline acetyltransferase development factor
    • McManaman, J., Crawford, F., Clark, R., Richker, J., and Fuller, F. 1989. Multiple neurotrophic factors from skeletal muscle: demonstration of effects of basic fibroblast growth factor and comparisons with the 22-kilodalton choline acetyltransferase development factor. J. Neurochem. 53:1763-1771.
    • (1989) J. Neurochem. , vol.53 , pp. 1763-1771
    • McManaman, J.1    Crawford, F.2    Clark, R.3    Richker, J.4    Fuller, F.5
  • 114
    • 0027414519 scopus 로고
    • Evidence that fibroblast growth factor 5 is a major muscle derived survival factor for cultured spinal motoneurons
    • Hughes, R. A., Sendtner, M., Goldfarb, M., Lindholm, D., and Thoenen, H. 1993. Evidence that fibroblast growth factor 5 is a major muscle derived survival factor for cultured spinal motoneurons. Neuron 10:369-377.
    • (1993) Neuron , vol.10 , pp. 369-377
    • Hughes, R.A.1    Sendtner, M.2    Goldfarb, M.3    Lindholm, D.4    Thoenen, H.5
  • 115
    • 0027233526 scopus 로고
    • Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation
    • Escary, J.-L., Perreau, J., Duménil, D., Ezine, S., and Brûlet, P. 1993. Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation. Nature 363:361-364.
    • (1993) Nature , vol.363 , pp. 361-364
    • Escary, J.-L.1    Perreau, J.2    Duménil, D.3    Ezine, S.4    Brûlet, P.5
  • 116
    • 0027722295 scopus 로고
    • Leukemia inhibitory factor mediates an injury response but not a target-directed developmental transmitter switch in sympathetic neurons
    • Rao, M. S., Sun, Y., Escary, J. L., Perreau, J., Tresser, S., Patterson, P. H., Zigmond, R. E., Brulet, P., and Landis, S. C. 1993. Leukemia inhibitory factor mediates an injury response but not a target-directed developmental transmitter switch in sympathetic neurons. Neuron 11:1175-1185.
    • (1993) Neuron , vol.11 , pp. 1175-1185
    • Rao, M.S.1    Sun, Y.2    Escary, J.L.3    Perreau, J.4    Tresser, S.5    Patterson, P.H.6    Zigmond, R.E.7    Brulet, P.8    Landis, S.C.9
  • 118
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor I (lgf-1) and type 1 IGF receptor (lgflr)
    • Liu, J.-P., Baker, J., Perkins, A. S., Robertson, E. J., and Efstratiadis, A. 1993. Mice carrying null mutations of the genes encoding insulin-like growth factor I (lgf-1) and type 1 IGF receptor (lgflr). Cell 75:59-72.
    • (1993) Cell , vol.75 , pp. 59-72
    • Liu, J.-P.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 119
    • 0027484249 scopus 로고
    • Disruption of the CNTF gene results in motor neuron degeneration
    • Masu, Y., Wolf, E., Holtmann, B., Sendtner, M., Brem, G., and Thoenen, H. 1993. Disruption of the CNTF gene results in motor neuron degeneration. Nature 365:27-32.
    • (1993) Nature , vol.365 , pp. 27-32
    • Masu, Y.1    Wolf, E.2    Holtmann, B.3    Sendtner, M.4    Brem, G.5    Thoenen, H.6
  • 120
    • 0029620955 scopus 로고
    • Essential function of LIF-receptor on motor neurons
    • Li, M., Sendtner, M., and Smith, A. 1995. Essential function of LIF-receptor on motor neurons. Nature 378:724-727.
    • (1995) Nature , vol.378 , pp. 724-727
    • Li, M.1    Sendtner, M.2    Smith, A.3
  • 124
    • 0028854836 scopus 로고
    • In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
    • Yan, Q., Matheson, C., and Lopez, O. T. 1995. In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373:341-344.
    • (1995) Nature , vol.373 , pp. 341-344
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3
  • 125
    • 0027281189 scopus 로고
    • Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF
    • Lohof, A. M., Ip, N. Y., and Poo, M. 1993. Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. Nature 363:350-353.
    • (1993) Nature , vol.363 , pp. 350-353
    • Lohof, A.M.1    Ip, N.Y.2    Poo, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.