Proliferation in the auditory receptor epithelium mediated by a cyclic AMP-dependent signaling pathway

Nature Medicine

Volumn 2, Issue 10, 1996, Pages 1136-1139

  Navaratnam, Dhasakumar S ^a   Su, Henry S ^a   Scott, Sean Patrick ^a   Oberholtzer, J Carl ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GENTAMICIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL REGENERATION; CHICKEN; COCHLEA; CONTROLLED STUDY; HAIR CELL; HEARING LOSS; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL;

1-METHYL-3-ISOBUTYLXANTHINE; 8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; CARBAZOLES; CHICKENS; COCHLEA; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA REPLICATION; ENZYME ACTIVATION; ENZYME INHIBITORS; FORSKOLIN; GENTAMICINS; HAIR CELLS; HEARING LOSS, SENSORINEURAL; INDOLES; ISOQUINOLINES; ORGAN CULTURE TECHNIQUES; PYRROLES; REGENERATION; SIGNAL TRANSDUCTION; SULFONAMIDES;

ANIMALIA; AVES; BACTERIA (MICROORGANISMS); GALLUS GALLUS;

EID: 0029794227     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1096-1136     Document Type: Article

References (25)

1. Nadol, J.B., Jr. Hearing loss. N. Engl. J. Med. 329, 1092-1102 (1993).
2. Convin, J.T. & Cotanche, D.A. Regeneration of sensory hair cells after acoustic trauma. Science 240, 1772-1774 (1988).
3. Ryals, B.M. & Rubel, E.W. Hair cell regeneration after acoustic trauma in adult Coturnix quail. Science 240, 1774-1776 (1988).
4. Lippe, W.R., Westbrook, E.W. & Ryals, B.M. Hair cell regeneration in the chicken cochlea following aminoglycoside toxicity. Hear. Res. 56, 203-210 (1991).
5. Cotanche, D.A. et al. Hair cell regeneration in the bird cochlea following noise damage or ototoxic drug damage. Anat. Embryol. (Berl). 189, 1-18 (1994).
6. Girod, D.A., Duckert, L.G. & Rubel, E.W. Possible precursors of regenerated hair cells in the avian cochlea following acoustic trauma. Hear. Res. 42, 175-194 (1989).
7. Corwin, J.T. et al. Hair cell regeneration: The identities of progenitor cells, potential triggers and instructive cues. Ciba Found. Symp. 160, 103-20 (1991).
8. Raphael, Y. Evidence for supporting cell mitosis in response to acoustic trauma in the avian inner ear. J. Neurocytol. 21, 663-671 (1992).
9. Hashino, E. et al. Hair cell regeneration in the adult budgerigar after kanamycin ototoxicity. Hear. Res. 59, 46-58 (1992).
10. Hashino, E. & Salvi, R.J. Changing spatial patterns of DNA replication in the noise-damaged chick cochlea. J. Cell Sci. 105, 23-31 (1993).
11. Stone, J.S. & Cotanche, D.A. Identification of the timing of S phase and the patterns of cell proliferation during hair cell regeneration in the chick cochlea. J. Comp. Neurol. 341, 50-67 (1994).
12. Bhave, S.A. et al. Cell cycle progression in gentamicin-damaged avian cochleas. J. Neurosci. 15, 4618-4628 (1995).
13. McFadden, E.A. & Saunders, J.C. Recovery of auditory function following intense sound exposure in the neonatal chick. Hear. Res. 41, 205-215 (1989).
14. Tucci, D.L. & Rubel, E.W. Physiologic status of regenerated hair cells in the avian inner ear following aminoglycoside ototoxicity. Otolaryngol. Head Neck Surg. 103, 443-450 (1990).
15. Jorgensen, J.M. & Mathiesen, C. The avian inner ear: Continuous production of hair cells in vestibular sensory organs, but not in the auditory papilla. Naturwissenschaften 75, 319-320 (1988).
16. Lambert, P.R. Inner ear hair cell regeneration in a mammal: Identification of a triggering factor. Laryngoscope 104, 701-718 (1994).
17. Yamashita, H. & Oesterle, E.C. Induction of cell proliferation in mammalian inner-ear sensory epithelia by transforming growth factor alpha and epidermal growth factor. Proc. Natl. Acad. Sci. USA 92, 3152-3155 (1995).
18. Dumont, J.E., Jauniaux, J.C. & Roger, P.P. The cyclic AMP-mediated stimulation of cell proliferation. Trends Biochem. Sci. 14, 67-71 (1989).
19. Marx, J. Two major signal pathways linked. Science 262, 988, 990 (1993).
20. Oesterle, E.C. et al. Hair-cell regeneration in organ cultures of the postnatal chicken inner ear. Hear. Res. 70, 85-108 (1993).
21. Forge, A. & Richardson, G. Freeze fracture analysis of apical membranes in cochlear cultures: Differences between basal and apical-coil outer hair cells and effects of neomycin. J. Neurocytol. 22, 854-867 (1993).
22. Bartolami, S., Goodyear, R. & Richardson, G. Appearance and distribution of the 275 kD hair-cell antigen during development of the avian inner ear. J. Comp. Neurol. 314, 777-788 (1991).
23. Oberholtzer, J.C. et al. The 28-kDa calbindin-D is a major calcium-binding protein in the basilar papilla of the chick. Proc. Natl. Acad. Sci. USA 85, 3387-3390 (1988).
24. Dartt, D.A. et al. Cyclic nucleotide-dependent enzyme secretion in the rat lacrimal gland. J. Physiol. (Lond.) 352, 375-384 (1984).
25. Hentrich, F., Gothert, M. & Greschuchna, D. Involvement of cAMP in modulation of noradrenaline release in the human pulmonary artery. Naunyn Schmiedebergs Arch. Pharmacol. 330, 245-247 (1985).