Impaired immunosuppressive response to ultraviolet radiation in interleukin-10-deficient mice

Journal of Investigative Dermatology

Volumn 107, Issue 4, 1996, Pages 553-557

  Beissert, Stefan ^a,c   Hosoi, Junichi ^a   Kühn, Ralf ^b   Rajewsky, Klaus ^b   Müller, Werner ^b   Granstein, Richard D ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Contact hypersensitivity; Delayed type hypersensitivity; Immunology

Indexed keywords

HAPTEN; INTERLEUKIN 10;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTACT ALLERGY; CONTROLLED STUDY; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; ULTRAVIOLET B RADIATION;

EID: 0029794198     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12582809     Document Type: Article

References (29)

1. Baadsgaard O, Fox DA, Cooper KD: Human epidermal cells from ultraviolet light-exposed skin preferentially activate autoreactive CD4+2H4+ suppressor-inducer lymphocytes and CD8+ suppressor/cytotoxic lymphocytes. J Immunol 140:1738-1744, 1988
2. Beissert S, Hosoi J, Grabbe S, Asahina A, Granstein RD: IL-10 inhibits tumor antigen presentation by epidermal antigen-presenting cells. J Immunol 154:1280-1286, 1995
3. Berg DJ, Leach MW, Kühn R, Rajewsky K, Müller W, Davidson NJ, Rennick D: Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses. J Exp Med 182:99-108, 1995
4. Chen Q, Daniel V, Maher DW, Hersey P: Production of IL-10 by melanoma cells: examination of its role in immunosuppression mediated by melanoma. Int J Cancer 56:755-760, 1994
5. Cooper KD, Fox P, Neises G, Katz SI: Effects of ultraviolet radiation on human epidermal cell alloantigen presentation: initial depression of Langerhans cell-dependent function is followed by the appearance of T6-DR+ cells that enhance epidermal alloantigen presentation. J Immunol 134:129-137, 1985
6. De Fabo EC, Noonan FP: Mechanism of immune suppression by ultraviolet irradiation in vivo. I. Evidence for the existence of a unique photoreceptor in the skin and its role in photoimmunology. J Exp Med 157:84-98, 1983
7. Devary Y, Gottlieb RA, Smeal T, Karin M: The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell 71:1081-1091, 1992
8. Devary Y, Rosette C, DiDonato JA, Karin M: NFκB activation by ultraviolet light not dependent on a nuclear signal. Science 261:1442-1445, 1993
9. Engelberg D, Klein C, Martinetto H, Struhl K, Karin M: The UV response involving the Ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals. Cell 77:381-390, 1994
10. Enk AH, Katz SI: Identification and induction of keratinocyte-derived IL-10. J Immunol 149:92-95, 1992
11. Everett MA, Yeargers E, Sayre RM, Olson RL: Penetration of epidermis by ultraviolet rays. Photochem Photobiol 5:533-542, 1965
12. Fisher MS, Kripke ML: Suppressor T lymphocytes control the development of primary skin tumors in ultraviolet-irradiated mice. Science 216:1133-1134, 1982
13. Grabbe S, Bruvers S, Granstein RD: Interleukin 1α but not transforming growth factor β inhibits tumor antigen presentation by epidermal antigen-presenting cells. J Invest Dermatol 102:67-73, 1994
14. Grabbe S, Granstein RD: Mechanisms of ultraviolet radiation carcinogenesis. Chem Immunol 58:291-313, 1994
15. Kim J, Modlin RL, Moy RL, Dubinett SM, McHugh T, Nickoloff BJ, Uyemura K: IL-10 production in cutaneous basal and squamous cell carcinomas. J Immunol 155:2240-2247, 1995
16. Kim TY, Kripke ML, Ullrich S.E: Immunsuppressive factors released from UV-irradiated epidermal cells: selective defects on the generation of contact and delayed hypersensitivty after exposure to UVA and UVB radiation. J Invest Dermatol 94:26-32, 1990
17. Köck A, Schwarz T, Kirnbauer R, Urbanski A, Perry P, Ansel JC, Luger TA: Human keratinocytes are a source for tumor necrosis factor: evidence for synthesis and release upon stimulation with endotoxin and ultraviolet light. J Exp Med 172:1609-1614, 1990
18. Kripke ML: Effects of irradiation on tumor immunity. J Nat Cancer Inst 82:1392-1396, 1990
19. Kühn R, Lohler J, Rennick D, Rajewsky K, Müller W: Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75:263-274, 1993
20. Moledijk A, van Gurp RJHLM, Donselaar IG, Benner R: Suppression of delayed-type hypersensitivity to histocompatibility antigens by ultraviolet radiation. Immunol 62:299-305, 1987
21. Radler-Pohl A, Sachsenmaier C, Gebel S, Auer H-P, Bruder JT, Rapp U, Angel P, Rahmsdorf HJ, Herrlich P: UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase. EMBO J 12:1005-1012, 1993
22. Rivas JM, Ullrich SE: Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes. J Immunol 149:3865-3871, 1992
23. Rivas JM, Ullrich SE: The role of IL-4, IL-10, and TNF-α in the immune suppression induced by ultraviolet radiation. J Leuk Biol 56:769-775, 1994
24. Schwarz A, Grabbe S, Riemann H, Aragane Y, Simon M, Manon S, Andrade S, Luger T A, Zlotnik A, Schwarz T: In vivo effects of interleukin-10 on contact hypersensitivity and delayed-type hypersensitivity reactions. J Invest Dermatol 103:211-216, 1994
25. Tan EM, Stoughton RB: Ultraviolet light induced damage to desoxyribonucleic acid in human skin. J Invest Dermatol 52:537-542, 1969
26. Ullrich SE: Suppression of the immune response to alloantigeneic histocampatibility antigens by a single exposure to ultraviolet radiation. Transplantation 42:287-291, 1986
27. Wolf P, Yarosh DB, Kripke M: Effects of sunscreens and a DNA exicion repair enzyme on ultraviolet radiation-induced inflammation, immune suppression, and cyclobutane pyrimidine dimer formation in mice. J Invest Dermatol 101:523-527, 1993
28. Yoshikawa T, Rae V, Bruins-Slot W, Van den Berg J-W, Taylor JR, Streilein JW: Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in humans. J Invest Dermatol 95:530-536, 1990
29. Yoshikawa T, Streilein JW: Tumor necrosis factor-alpha and ultraviolet B light have similar effects on contact hypersensitivity in mice. Reg Immunol 3:139-144, 1990