Is the increase in renal papillary phospholipid biosynthesis a protective mechanism against injury?

Kidney and Blood Pressure Research

Volumn 19, Issue 1, 1996, Pages 38-45

  Setton Avruj, Clara P ^a   Fernández Tomé, Maria Del Carmen ^a   Negri, Armando ^b   Scerbo, Adriana ^b   Arrizurieta, Elvira ^b   Sterin Speziale, Norma B ^a  

^a Ciudad Autonoma de Buenos Aires   (Argentina)

^b INSTITUTO DE INVESTIGACIONES MÉDICAS ALFREDO LANARI   (Argentina)

Author keywords

Acute renal failure; Mercuric chloride; Renal cortex; Renal medulla; Renal papilla; Thyroxine

Indexed keywords

MERCURIC CHLORIDE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; PHOSPHORUS 32; SPHINGOMYELIN; THYROXINE;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEFENSE MECHANISM; KIDNEY CORTEX; KIDNEY MEDULLA; KIDNEY PAPILLA; MALE; NONHUMAN; PHOSPHOLIPID METABOLISM; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; RAT;

EID: 0029794193     PISSN: 14204096     EISSN: 14230143     Source Type: Journal    
DOI: 10.1159/000174044     Document Type: Article

References (26)

1. Andrews PM, Chung EM: High dietary protein regimes provide singificant protection from mercury nephrotoxicity in rats. Toxicol Appl Pharmacol 1990; 105:288-304.
2. Ganote CE, Reimer KA, Jennings RB: Acute mercuric chloride nephrotoxicity: An electron microscopic and metabolic study. Lab Invest 1974:31:633-647.
3. Toback FG, Havener LJ, Dodd RC, Spargo BH: Phospholipid metabolism during renal regeneration after acute tubular necrosis. AmJ Physiol 1977:232: E216-E222.
4. Toback FG: Amino acid enhancement of renal regeneration after acute tubular necrosis. Kidney bit 1977;12:193-198.
5. Negri AL, Alvarez C, Fernandez MC, Kahane VL, Sterin-Speziale NB, Arrizurieta E: Accelerated recovery from toxic acute renal failure with thyroxine: Stimulation of renal phospholipid biosynthesis. Ren Fail 1994; 16:19-26.
6. Chien KR, Pfau RG, Faber JL: Ischemic myo-cardinal cell injury. Prevention by chlorproma-zine ofan accelerated phospholipid degradation and associated membrane dysfunction. Am J Pathol 1979;97:505-529.
7. Chien KR, Reeves JP, Buja LM, Bontc F, Parkey RW, Willerson JT: Phospholipid alterations in canine ischemic myocardium. Temporal and topographical correlations with Tc-99nt-PPi accumulation and in vitro sarcolemmal Ca permeability defect. Circ Res 1981:48:711-719.
8. Sterin-Speziale NB, Kahane VL, Setton CP, Fernandez MC, Speziale EH: Compartmental study of rat renal phospholipid metabolism. Lipids 1992:27:10-14.
9. Bliglt EG, Dyer WJ: A rapid method of total lipid extraction and purification. Can J Biolchem Physiol 1959;39:911-917.
10. Weiss SJ, Me Kinney JS, Putney JW Jr: Regulation of phosphatidate synthesis by secreta-gogucs in parotid acinar cells. Biochem J 1982: 204:587-592.
11. Bartlett GR: Phosphorus assay in column chromatography. J BiolChem 1959:234:466-468.
12. Wirthensohn G, Lcfrank S, Wirthensohn K, Gudcr WG: Phospholipid metabolism in rat kidney cortical tubules. I. Effect of renal infstrates. Biochim Biophys Acta 1984:795:392-400.
13. Boon AM, Bcrcsford BJ, Mellors A: A tumor promoter enhances the phosphorylation of polyphosphoinositides while decreasing phos-phatidylinositol labelling in lymphocytes. Biochem Biophys Res Commun 1985; 129:431-438.
14. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193:265-275.
15. Green DE, Mitchell F, Blondin GA: Phospholipids as the molecular instruments of ion solute transport in biological membranes. Proc Natl AcadSci USA 1980;77:257-261.
16. Lipsky JJ, Lilntan PS: Neomycin inhibition of adenosine triphosphatase evidence for a neomycin phospholipid interaction. Antimicrob Agents Chcmothcr 1980; 18:532-536.
17. Yeaglc PL: Lipid regulation of cell membrane structure and function. FASEB J 1989:3:1833-1842.
18. Billah MM, Anthes JC: The regulation and cellular functions of phosphatidylcholine hydrolysis. Biochem J 1990;269:281-291.
19. Pfcilschifter JM: Cellular signalling in the kidney: The role of inositol lipids. Renal Physiol Biochem 1989:12:1-31.
20. Ko KWS, Cook HW, Vance DE: Reduction or phosphatidylcholine turnover in a Nb-2 lymphoma cell line after prolactin treatment. J Biol Chem 1986:261:7846-7852.
21. Toback FG: Phosphatidylcholine metabolism during renal growth and regenration. Am J Physiol 1984:246: F249-F259.
22. 2+], transient in the rat early proximal tubule. Biochem Biophys Res Commun 1990;173:606-613.
23. Zalups RK, Cherian MG, Barfuss DW: Mcrcu-ry-metallothionein and the renal accumulation and handling of mercury. Toxicology 1993:83: 61-78.
24. Dorian C, Gattone VH, Klaasen CD: Accumulation and degradation of the protein moiety of cadmium-metallothioncin in the mouse kidney. Toxicol Appl Pharmacol 1992; 117:242-248.
25. Vcstergaard P, Shaikh ZA: The nephrotoxicity of intravenously administered eadmium-metal-lothionein: Effect of dose, mode of administration, and preexisting renal cadmium burden. Toxical Appl Pharmacol 1994;126:240-247.
26. Char HM, Satoh M, Zalups RK, Cherian MG: Exogenous metallothionein and renal toxicity of cadmium and mercury in rats. Toxicology 1992;76:15-26.