Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery

European Journal of Anaesthesiology

Volumn 13, Issue 5, 1996, Pages 485-491

  Chen, P P ^a   Chui, P T ^a   Gin, T ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Pharmacology, ondansetron, metoclopramide; Vomiting, nausea, antiemetics

Indexed keywords

ATRACURIUM; ISOFLURANE; METHADONE; METOCLOPRAMIDE; NITROUS OXIDE; ONDANSETRON; OPIATE; OXYGEN; THIOPENTAL;

ABDOMINAL SURGERY; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; INCIDENCE; INTRAVENOUS DRUG ADMINISTRATION; NAUSEA; PERITONEUM; POSTOPERATIVE COMPLICATION; RANDOMIZED CONTROLLED TRIAL; RESPIRATION DEPRESSION; VOMITING;

EID: 0029793871     PISSN: 02650215     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003643-199609000-00012     Document Type: Article

References (23)

1. Bodner M, White PF. Antiemetic efficacy of ondansetron after outpatient laparoscopy. Anesth Analg 1991; 73: 250-254.
2. Scuderi P, Wetchler B, Sung YF et al. Treatment of post-operative nausea and vomiting after outpatient surgery with the 5-HT3 antagonist ondansetron. Anesthesiology 1993; 78: 15-20.
3. McKenzie R, Kovac A, O'Connor T et al. Comparison of ondansetron vs placebo in the prevention of post-operative nausea and vomiting in women undergoing ambulatory gynecologic surgery. Anesthesiology 1993; 78: 21-28.
4. Suen TKL, Gin T, Chen PP, Rowbottom YM, Critchley LAH, Ray AK. Ondansetron 4 mg for the prevention of nausea and vomiting after minor laparoscopic gynaecological surgery. Anaesth Intensive Care 1994; 22: 142-146.
5. Alon E, Himmelseher S. Ondansetron in the treatment of postoperative vomiting: A randomized double-blind comparison with droperidol and metoclopramide. Anesth Analg 1992; 75: 561-565.
6. Raphael JH, Norton AC. Antiemetic efficacy of prophylactic ondansetron in laparoscopic surgery: Randomized, double-blind comparison with metoclopramide. Br J Anaesth 1993; 71: 845-848.
7. Alon E, Lenzlinger PM, Pasch T. Ondansetron 4 mg vs droperidol 1.25 mg in the prophylaxis of postoperative nausea and vomiting after alfentanil-supplemented inhalational anaesthesia. Br J Anaesth 1993; 70(Suppl): A12.
8. Gan TJ, Collis R, Hetreed M. Double-blind comparison of ondansetron, droperidol and saline in the prevention of nausea and vomiting. Br J Anaesth 1994; 72: 544-547.
9. Geiger C, Kick O, Bohrer H, Motsch J, Martin E. Comparison of ondansetron, metoclopramide and droperidol for the prophylaxis of emetic symptoms after gynaecological laparascopic procedures. Br J Anaesth 1993; 70(Suppl): A14.
10. Roberson CR, Walker RT. Comparative value of ondansetron and metoclopramide in the prevention of post-op nausea and vomiting. Anesth Analg 1993; 76: S350.
11. Malins AF, Field JM, Nesling PM, Cooper GM. Nausea and vomiting after gynaecological laparascopy: comparison of premedication with oral ondansetron, metoclopramide and placebo. Br J Anaesth 1994; 72: 231-233.
12. Watcha M, White PF. Postoperative nausea and vomiting. Its etiology, treatment and prevention. Anesthesiology 1992; 77: 162-184.
13. Chui PT, Gin T. A double-blind randomised trial comparing postoperative analgesia after perioperative loading doses of methadone or morphine. Anaesth Intensive Care 1992; 20: 46-51.
14. Gourlay GK, Willis RJ, Lamberty J. A double-blind comparison of the efficacy of methadone and morphine in postoperative pain control. Anesthesiology 1986; 64: 322-327.
15. Kenny GNC, Oates DL, Leeser J et al. Efficacy of orally administered ondansetron in the prevention of post-operative nausea and vomiting: A dose ranging study. Br J Anaesth 1992; 68: 466-470.
16. Madej TH, Simpson KH. Comparison of the use of domperidone, droperidol and metoclopramide in the prevention of nausea and vomiting following major gynaecological surgery. Br J Anaesth 1986; 58: 884-887.
17. Haigh CG, Kaplan LA, Durham JM, Dupeyron JP, Harmer M, Kenny GNC. Nausea and vomiting after gynaecological surgery: A meta-analysis of factors affecting their incidence. Br J Anaesth 1993; 71: 517-522.
18. Harrington RA, Hamilton CW, Brogden RN, Linkewich JA, Romankiewicz JA, Heel RC. Metoclopramide: An updated review of its pharmacological properties and clinical use. Drugs 1983; 25: 451-494.
19. 3 antagonists in postoperative nausea and vomiting. Br J Anaesth 1992; 69(Suppl.1): 63S-68S.
20. Rowbotham DJ. Current management of postoperative nausea and vomiting. Br J Anaesth 1992; 69(Suppl.1): 46S-59S.
21. Ummenhofer W, Frei FJ, Urwyler A, Kern C, Drewe J. Effects of ondansetron in the prevention of postoperative nausea and vomiting in children. Anesthesiology 1993; 81: 804-810.
22. Furst SR, Rodarte A. Prophylactic antiemetic treatment with ondansetron in children undergoing tonsillectomy. Anesthesiology 1994; 81: 799-803.
23. Koch KL, Xu L, Bingaman S et al. Effects of ondansetron on morphine-induced nausea, vasopressin and gastric myoelectrical activity in healthy human. Gastroenterology 1993; 104(Suppl.): A535.