메뉴 건너뛰기




Volumn 74, Issue 9, 1996, Pages 489-495

Myocardial β-adrenergic receptor signaling in vivo: Insights from transgene mice

Author keywords

G protein coupled receptor kinase; Myocardial contractility; Transgenic mice; Adrenergic receptor kinase; P Adrenergic receptor

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; HEART RECEPTOR; PROTEIN KINASE; RECEPTOR PROTEIN;

EID: 0029793560     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00204974     Document Type: Review
Times cited : (33)

References (32)
  • 1
    • 0028908910 scopus 로고
    • Plasma norepinephrine and mortality
    • Cohn JN (1995) Plasma norepinephrine and mortality. Clin Cardiol 18 [Suppl]:I9-I12
    • (1995) Clin Cardiol , vol.18 , Issue.SUPPL.
    • Cohn, J.N.1
  • 4
    • 0027819354 scopus 로고
    • Beta-adrenoceptors in cardiac disease
    • Brodde OE (1993) Beta-adrenoceptors in cardiac disease. Pharmac Ther 60:405-430
    • (1993) Pharmac Ther , vol.60 , pp. 405-430
    • Brodde, O.E.1
  • 6
    • 0024397065 scopus 로고
    • Phosphorylation sites on two domains of the beta 2-adrenergic receptor are involved in distinct pathways of receptor desensitization
    • Hausdorff WP, Bouvier M, O'Dowd BF, Irons GP, Caron MG, Lefkowitz RJ (1989) Phosphorylation sites on two domains of the beta 2-adrenergic receptor are involved in distinct pathways of receptor desensitization. J Biol Chem 264:12657-12665
    • (1989) J Biol Chem , vol.264 , pp. 12657-12665
    • Hausdorff, W.P.1    Bouvier, M.2    O'Dowd, B.F.3    Irons, G.P.4    Caron, M.G.5    Lefkowitz, R.J.6
  • 7
    • 0027375964 scopus 로고
    • Molecular mechanisms of membrane receptor desensitization
    • Lohse MJ (1993) Molecular mechanisms of membrane receptor desensitization. Bioch Bioph Acta 1179:171-188
    • (1993) Bioch Bioph Acta , vol.1179 , pp. 171-188
    • Lohse, M.J.1
  • 8
    • 0027194487 scopus 로고
    • G protein-coupled receptor kinases
    • Lefkowitz RJ (1993) G protein-coupled receptor kinases Cell 74:409-412
    • (1993) Cell , vol.74 , pp. 409-412
    • Lefkowitz, R.J.1
  • 9
    • 0027368165 scopus 로고
    • Structure and mechanism of the G protein-coupled receptor kinases
    • Inglese J, Freedman NJ, Koch WJ, and Lefkowitz RJ (1993) Structure and mechanism of the G protein-coupled receptor kinases. J Biol Chem 268:23735-23738
    • (1993) J Biol Chem , vol.268 , pp. 23735-23738
    • Inglese, J.1    Freedman, N.J.2    Koch, W.J.3    Lefkowitz, R.J.4
  • 11
    • 0027481032 scopus 로고
    • The binding site for the βγ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase
    • Koch WJ, Inglese J, Stone WC, Lefkowitz RJ (1993) The binding site for the βγ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase. J Biol Chem 268:8256-8260
    • (1993) J Biol Chem , vol.268 , pp. 8256-8260
    • Koch, W.J.1    Inglese, J.2    Stone, W.C.3    Lefkowitz, R.J.4
  • 12
    • 0028300574 scopus 로고
    • Identification, purification and characterization of GRK5, a member of the family of G protein receptor kinases
    • Premont RT, Koch WJ, Inglese J, Lefkowitz RJ (1994) Identification, purification and characterization of GRK5, a member of the family of G protein receptor kinases. J Biol Chem 269:6832-6841
    • (1994) J Biol Chem , vol.269 , pp. 6832-6841
    • Premont, R.T.1    Koch, W.J.2    Inglese, J.3    Lefkowitz, R.J.4
  • 13
    • 0027495684 scopus 로고
    • New roles for G-protein βγ-dimers in transmembrane signalling
    • Clapham DE, Neer EJ (1993) New roles for G-protein βγ-dimers in transmembrane signalling. Nature 365:403-406
    • (1993) Nature , vol.365 , pp. 403-406
    • Clapham, D.E.1    Neer, E.J.2
  • 15
    • 0028912946 scopus 로고
    • Mechanisms of adenosine-mediated actions on cellular and clinical cardiac electrophysiology
    • Shen W, Kurachi Y (1995) Mechanisms of adenosine-mediated actions on cellular and clinical cardiac electrophysiology. Mayo Clin Proc 70:274-291
    • (1995) Mayo Clin Proc , vol.70 , pp. 274-291
    • Shen, W.1    Kurachi, Y.2
  • 17
  • 18
    • 0026047210 scopus 로고
    • Experimental issues in assessment of G protein function in cardiac disease
    • Feldman AM (1991) Experimental issues in assessment of G protein function in cardiac disease. Circulation 84:1852-1861
    • (1991) Circulation , vol.84 , pp. 1852-1861
    • Feldman, A.M.1
  • 20
    • 0029010634 scopus 로고
    • Alterations of β-adrenoreceptor-G-protein-regulated adenylyl cyclase in heart failure
    • Bohm M (1995) Alterations of β-adrenoreceptor-G-protein-regulated adenylyl cyclase in heart failure. Mol Cell Biochem 147:147-160
    • (1995) Mol Cell Biochem , vol.147 , pp. 147-160
    • Bohm, M.1
  • 21
    • 0027497584 scopus 로고
    • Altered expression of β-adrenergic receptors in the failing human heart
    • Ungerer M, Bohm M, Elce JS, Erdman E, Lohse MJ (1993) Altered expression of β-adrenergic receptors in the failing human heart. Circulation 87:454-463
    • (1993) Circulation , vol.87 , pp. 454-463
    • Ungerer, M.1    Bohm, M.2    Elce, J.S.3    Erdman, E.4    Lohse, M.J.5
  • 22
    • 0028985998 scopus 로고
    • Reduced β-adrenergic receptor activation decreases G-protein expression and β-adrenergic receptor kinase activity in porcine heart
    • Ping P, Gelzer-Bell R, Roth DA, Kiel D, Insel PA, and Hammond HK (1995) Reduced β-adrenergic receptor activation decreases G-protein expression and β-adrenergic receptor kinase activity in porcine heart. J Clin Invest 95:1271-1280
    • (1995) J Clin Invest , vol.95 , pp. 1271-1280
    • Ping, P.1    Gelzer-Bell, R.2    Roth, D.A.3    Kiel, D.4    Insel, P.A.5    Hammond, H.K.6
  • 26
    • 0029061324 scopus 로고
    • Reciprocally altered cardiac-function in transgenic mice overexpressing the β-adrenergic receptor kinase or a βARK inhibitor
    • Koch WJ, Rockman HA, Samama P, Hamilton R, Bond RA, Milano CA, Lefkowitz RJ (1995) Reciprocally altered cardiac-function in transgenic mice overexpressing the β-adrenergic receptor kinase or a βARK inhibitor. Science 268:1350-1353
    • (1995) Science , vol.268 , pp. 1350-1353
    • Koch, W.J.1    Rockman, H.A.2    Samama, P.3    Hamilton, R.4    Bond, R.A.5    Milano, C.A.6    Lefkowitz, R.J.7
  • 31
    • 0025873338 scopus 로고
    • Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy
    • Rockman HA, Ross RS, Harris AN, Knowlton KU, Steinhelper ME, Field L, Ross J Jr, Chien KR (1991) Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proc Natl Acad Sci USA 88:8277-8281
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8277-8281
    • Rockman, H.A.1    Ross, R.S.2    Harris, A.N.3    Knowlton, K.U.4    Steinhelper, M.E.5    Field, L.6    Ross Jr., J.7    Chien, K.R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.