Pharmacodynamic effects of ciprofloxacin, fleroxacin and lomefloxacin in vivo and in vitro

Chemotherapy

Volumn 42, Issue 5, 1996, Pages 354-362

  Fuentes, F ^a   Martin M M ^a   Izquierdo, J ^a   Gomez Lus M L ^a   Prieto, J ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Ciprofloxacin; Fleroxacin; Lomefloxacin; Postantibiotic effect; Subinhibitory concentrations

Indexed keywords

CIPROFLOXACIN; FLEROXACIN; LOMEFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; KINETICS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PHARMACODYNAMICS; POSTANTIBIOTIC EFFECT; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

EID: 0029793193     PISSN: 00093157     EISSN: 14219794     Source Type: Journal    
DOI: 10.1159/000239467     Document Type: Article

References (33)

1. Bigger JW: The bactericidal action of penicillin on Staphylococcus pyogenes. Ir J Med Sei 1944:227:533-568.
2. McDonald PJ, Craig WA, Kunin CM: Persistent effect of antibiotics on Staphylococcus aureus after exposure for limited periods of time. J Infect Dis 1977;135:217-223.
3. Cars O, Odenholt-Tornqvist I: The post-antibiotic sub-MIC effect in vitro and in vivo. J Antimicrob Che-mother 1993:3l(suppl D): 159-166.
4. Odenholt-Tornqvist I: Studies on the postantibiotic sub-MIC effect of meropencm. J Antimicrob Che-mothcr 1993;31:881-892.
5. Hesen MT, Pitsakis PG, Levison ME: Absence of postantibiotic eifect in experimental Pseudomonas endocarditis treated with imipenem, with or without gentamicin. J Infect Dis 1988;158:542-548.
6. Odenholt I, Holm SE, Cars O: Effects of supra and sub-MIC benzyl-penicillin concentrations on group A ß-haemolytic streptococci during the postantibiotic phase in vivo. J Antimicrob Chemother 1990;26: 193-201.
7. Gudmundsson S, Vogelman B, Craig WA: The in vivo postantibiotic effect of imipcnem and other new antimicrobials. J Antimicrob Che-mother 1986; 18(suppl E):67-73.
8. Renneberg J, Wälder M: Postantibiotic effects of imipenem, norfloxacin and amikacin in vitro and in vivo. Antimicrob Agents Chemother 1989:33:1714-1720.
9. Fliickiger U, Segessenmann C, Gerber U: Integration of pharmacokinetics and pharmacodynamics of imipenem in a human-adapted mouse model. Antimicrob Agents Chemother 1991:35:1905-1910.
10. Rvan D, Cars O: Antibiotic assays in muscle: Are conventional tissue levels misleading as indicators of the antibacterial activity? Scand J Infect Dis 1980:12:307-309.
11. Craig WA, Gudmundsson S: The postantibiotic effect; in Lorian V (cd): Antibiotics in Laboratory Medicine. ed 3. Baltimore. Williams & Wilkins. 1991. pp 403-431.
12. Guan L, Blumenthal RM, Burnham JC: Analysis of macromolccular biosynthesis to define quinolone-induced postantibiotic effect in Escherichia coli. Antimicrob Agents Chemother 1992:36:2118-2124.
13. Courtright JB, Turowski DA, Sonstein SA: Alteration of bacterial DNA structure, gene expression, and plasmic encoded antibiotic resistance following exposure to en-oxacin. J Antimicrob Chemother 1988:21 (suppl B):l-18.
14. Jones RN, Barry AL, Gavan TL, Washington JA II: Susceptibility tests: Microdilution and macrodilution broth procedures: in Lennette EH. Balows A. Hausier WJ, Shado-my HJ (eds): Manual of Clinical Microbiology. Washington. American Society for Microbiology. 1985. pp 972-977.
15. Odenholt-Tornqvist I, Lowdin E, Cars O: Pharmacodynamic effects of subinhibitory concentrations of β-lactams antibiotics in vitro. Antimicrob Agents Chemother 1991: 35:1834-1839.
16. Roosendaal R, Bakker-Woudenberg AJM, van der Berghe, van Raffe M, Michel MF: Continuous versus intermittent administration of ceftazidime in experimental Klebsiella pneumoniae pneumonia in normal and leukopenic rats. Antimicrob Agents Chemother 1986:30:403-408.
17. Vogelman B, Gudmundsson S, Tur-nidge J, Leggett J, Craig WA: In vivo postantibiotic effect in a thigh infection model in neutropenic mice. J Infect Dis 1988:157:287-298.
18. Debbia EA, Pesce A, Schito GC: In vitro assessment of the postantibiotic effect of lomcfloxacin against Gram-positive and Gram-negative pathogens. Am J Med 1992;92:45-47.
19. Guan L, Burnham JC: Postantibiotic effect of CI-960, enoxacin and ciprofloxacin on E. coli: Effect on morphology and haemolysin activity. J Antimicrob Chemother 1992; 29:529-538.
20. Gould IM, Jason AC, Milne K: Postantibiotic effect and bacterial killing by ciprofloxacin and imipenem alone or in combination. Rev Infect Dis 1989:1 1:957-958.
21. Mingucz F, Ramos C, Barrientos S, LoscosA, Prieto J: Postantibiotic effect of ciprofloxacin compared with that of five quinolones. Chemotherapy 1991;37:420-425.
22. Rustige C, Wiedemann B: Antibacterial activity of lomcfloxacin in a pharmacokinetic in vitro model. Antimicrob Agents Chemother 1990;34:1107-1111.
23. Sandfor MD, Jones RN: Postantibiotic effects of E-4868 and OPC-17116. J Antimicrob Chemother 1993:32:916-917.
24. Craig WA: Post-antibiotic effects in experimental infection models: Relationship to in vitro phenomena and to treatment of infection in man. J Antimicrob Chemother 1993:31 (suppl D): 149-158.
25. Ingerman MJ, Pitsakis PG, Rosenberg AF, Levison ME: The importance of pharmacodynamics in determining the dosing interval in therapy for experimental Pseudomonas endocarditis in the rat. J Infect Dis 1986;153:707-714.
26. Minguez F, Izquierdo J, Martin MM, Fuentes F, Prieto J: In vivo postantibiotic effect of isepamicin and other aminoglycosides in a thigh infection model in neutropenic mice. Chemotherapy 1992:38:179-184.
27. Martin MM, Fuentes F, Izquierdo J, Gomcz-Lus ML, Prieto J: In vivo and in vitro study of the postantibiotic effect of meropcnem. J Antimicrob Chemother 1993:32:917-918.
28. Fernandes PB: Mode of action, and in vitro and in vivo activities of fluoroquinolones. J Clin Pharmacol 1988;28:156-168.
29. Sandc MA, Korzeniowski OM, Allegro GM, Brennan RO, Zak O, Scheld WM: Intermittent or continuous therapy of experimental meningitis due to S. pneumoniae in rabbits: Preliminary observations on the postantibiotic effect in vivo. Rev Infect Dis 1981:3:98-109.
30. Oshida T, Onta T, Nakanishi N, Matsishita T, Yamaguchi T: Activity of subminimal inhibitory concentrations of aspoxicillin in prolonging the postantibiotic elTcct against Staphylococcus aureus. J Antimicrob Chemother 1990:26:29-38.
31. Odenholt-Tornqvist I, Lowdin E, Cars O: Postantibiotic sub-MIC effects for vancomycin, roxithromycin. sparfloxacin and amikacin. Antimicrob Agents Chemother 1992: 36:1852-1858.
32. Odenholt-Tornqvist I, Bengtsson S: Postantibiotic effect and postantibiotic effect of subinhibitory concentrations of sparfloxacin on Gram-negative bacteria. Chemotherapy 1994:40:30-36.
33. Zhancl GC, Crampton J, Kim S, Ni-colle LE, Davidson RJ, Hoban DJ: Antimicrobial activity of subinhibitory concentrations of ciprofloxacin against Pseudomonas aeruginosa as determined by the killing curve method and the postantibiotic effect. Chemotherapy 1992:38:388-394.