Acyclovir prophylaxis in late pregnancy to prevent neonatal herpes: A cost-effectiveness analysis

Obstetrics and Gynecology

Volumn 88, Issue 4, 1996, Pages 603-610

  Randolph, Adrienne G ^a,b   Hartshorn, Rachel M ^a,b   Washington, A Eugene ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR;

ARTICLE; CESAREAN SECTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DRUG COST; FEMALE; GENITAL HERPES; HERPES SIMPLEX VIRUS 2; HIGH RISK PREGNANCY; HUMAN; INFECTION CONTROL; MAJOR CLINICAL STUDY; META ANALYSIS; MULTICENTER STUDY; NEWBORN INFECTION; ORAL DRUG ADMINISTRATION; PREGNANCY COMPLICATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECURRENT INFECTION; TREATMENT OUTCOME;

EID: 0029792833     PISSN: 00297844     EISSN: 1873233X     Source Type: Journal    
DOI: 10.1016/0029-7844(96)00261-X     Document Type: Article

References (40)

1. Gibbs RS, Mead PB. Preventing neonatal herpes—Current strategies. N Engl J Med 1992;326: 946-7.
2. YVhitlev R, Arvin A, Prober C, Corey L, Burchett S, Plotkin S, et al. Predictors of morbidity and mortality in neonates with herpes simplex virus infections. N Engl J Med 1991;324:450-4.
3. Sullender WM, Yasukawa LL, Schwartz M, Pereira L, Hensleigh PA, Prober CG, et al. Type specific antibodies to herpes simplex virus type 2 (HSV-2) glycoprotein G in pregnant women, infants exposed to maternal HSV-2 infection at delivery, and infants with neonatal herpes. J Infect Dis 1988;157:164-71.
4. Prober CG, Arvin AM. Genital herpes and the pregnant woman. Curr Clin Top Infect Dis 1989;10: 1-26.
5. Binkin NJ, Koplan JP. The high cost and low efficacy of weekly viral cultures for pregnant women with recurrent genital herpes: A reappraisal. Med Decis Making 1989;9: 225-30.
6. Chuang T. Neonatal herpes: Incidence, prevention and consequences. Am J Prev Med 1988;4: 47-53.
7. Scott LL. Perinatal herpes: Current status and future management strategies. Adv Obstet Gynecol 1996;3: 47-74.
8. Brown ZA, Vontver LA, Benedetti J, Critchlow CW, Sells CJ, Berry S, et al. Effects on infants of a first episode of genital herpes during pregnancy. N Engl J Med 1987;317: 1246-51.
9. Nahmias AJ, Keyserling HH, Kerrick GM. Herpes simplex. In: Remington JS, Klein JO, eds. Infectious diseases of the fetus and newborn infant. 2nd ed. Philadelphia: WB Saunders, 1983:636-78.
10. YVhitlev RJ, Corey L, Arvin A, Lakeman FD, Sumaya CV, Wright PF, et al. Changing presentation of herpes simplex virus infection in neonates. J Infect Dis 1988;158: 109-16.
11. Stone KM, Brooks CA, Guinan ME, Alexander ER. National surveillance for neonatal herpes simplex virus infections. Sex Transm Dis 1989;16: 152-6.
12. Arvin AM, Hensleigh PA, Prober CG, Au DS, Yasukawa LL, VVittek AE, et al. Failure of antepartum maternal cultures to predict the infant’s risk of exposure to herpes simplex virus at delivery. N Engl J Med 1986;315: 796-800.
13. American College of Obstetricians and Gynecologists Task Force on Herpes. Perinatal herpes simplex virus infections. ACOG technical bulletin no. 122. Washington, DC: American College of Obstetricians and Gynecologists. 1988.
14. Libman MD, Dascal A, Kramer MS, Mendelson J. Strategies for the prevention of neonatal infection with herpes simplex virus: A decision analysis. Rev Infect Dis 1991;13: 1093-104.
15. Randolph AG, Washington AE, Prober CG. Cesarean delivery for women presenting with genital herpes lesions: Efficacy, risks, and cost. JAMA 1993;270: 77-82.
16. Scott LL, Sanchez PJ, Jackson GL, Zerav F, Wendel GD. Acyclovir suppression to prevent cesarean delivery after first-episode genital herpes. Obstet Gynecol 1996;87: 69-73.
17. Pauker SG, Kassirer JP. Decision analysis. N Engl J Med 1987;3l6: 250-258.
18. Catalano PM, Merrit AO, Mead PB. Incidence of genital herpes simplex virus at the time of delivery in women with known risk factors. Am J Obstet Gynecol 1991;164: 1303-1306.
19. Wittek AE, Yeager AS, Au DS, Hensleigh PA. Asymptomatic shedding of herpes simplex virus from the cervix and lesion site during pregnancy. Am J Dis Child 1984;138: 439-442.
20. Carver JA, Arnoldi SH, Abel DM, Olson LC, Hall RT. Asymptomatic neonatal contamination with herpes simplex virus. J Perinatol 1988;8:14-6.
21. Cone RW, Hobson AC, Brown Z, Ashley R, Berry S, Winter C, et al. Frequent detection of genital herpes simplex virus DNA by polymerase chain reaction among pregnant women. JAMA 1994;272: 792-6.
22. Straus SE, Seidlin M, Takiff HE, Roonev IF, Felser JM, Smith HA, et al. Effect of oral acyclovir treatment on symptomatic and asymptomatic virus shedding in recurrent genital herpes. Sex Transm Dis 1989;16:107-113.
23. Rate of cesarean delivery—United States, 1991. MMWR 1993:42: 285-9.
24. Whitley R, Arvin A, Prober C, Burchett S, Corev L, Powell D, et al. A controlled trial comparing vidarabine with acvclovir in neonatal herpes simplex virus infection. N Engl J Med 1991;324:444-9.
25. Dascal A, Chan-Thim J, Morahan M, Portnov J, Mendelson J. Diagnosis of herpes simplex virus infection in a clinical setting by a direct antigen immunohistologic studv. J Clin Microbiol 1989;27: 700-4.
26. Red Book: Pharmacy’s fundamental reference. Montvale, New Jersev: Medical Economics Data Productions Co., 1994.
27. 7 current procedural terminology, 1994. Chicago: American Medical Association, 1994.
28. Department of Health and Human Serv ices. Physician fee schedule update for calendar vear 1994. Federal Register, vol. 58, 1993.
29. Mushinski M. Average charges for uncomplicated cesarean and vaginal deliveries, United States, 1993. Stat Bull Metrop Insur Co 1994;75:27-36.
30. Pettiti DB, Cefalo RC, Shapiro S, Whalley P. In-hospital maternal mortality in the United States: Time trends and relation to the method of delivery. Obstet Gynecol 1982;59: 6-12.
31. Waitzman NJ, Romano PS, Scheffler RM. Estimates of the economic costs of birth defects. Inquiry 1994;31: 188-305.
32. Balfour HH, Rotbart HA, Feldman S, Dunkle LM, Feder HM, Prober CG, et al. Acyclovir treatment of varicella in otherwise healthy adolescents. J Pediatr 1992;120:627-33.
33. Frenkel LM, Brown ZA, Bryson YJ, Corey L, Unadkat JD, Hen- sleigh PA, et al. Pharmacokinetics of acyclovir in the term human pregnancy and neonate. Am J Obstet Gynecol 1991;164: 569-576.
34. Sullender WM, Miller JL, Yasukawa LL, Bradley JS, Black SB, Yeager AS, et al. Humoral and cell-mediated immunity in neonates with herpes simplex virus infection. J Infect Dis 1987;155:28-37.
35. Bernstein DI, Lovett MA, Bryson YJ. The effects of acyclovir on antibody response to herpes simplex virus in primary genital herpetic infections. J Infect Dis 1984;150: 7-13.
36. Prober CG, Corey L, Brown ZA, Hensleigh PA, Frenkel LM, Brvson YJ, et al. The management of pregnancies complicated by genital infections with herpes simplex virus. Clin Infect Dis 1992;15:1031-8.
37. Moore HL, Szczech GM, Rodwell DE, Kapp RW, deMiranda P, Tucker WE, et al. Preclinical toxicology studies with acyclovir: Teratologic, reproductive and neonatal tests. Fundam Appl Toxicol 1983;3:560-8.
38. Klug S, Lewandowski C, Blankenbur G, Merker HJ, Neubert D. Effect of acyclovir of mammalian embryonic development in culture. Arch Toxicol 1985;58: 89-96.
39. Eldridge RR, Andrews EB, White A. Acyclovir pregnancy registry: International interim report, 1 June 1984 through 31 December 1994. Burroughs Wellcome Co, 1995.
40. Carnev O, Ross E, Ikkos G, Mindel A. The effect of suppressive oral acvclovir on the psychological morbidity associated with recurrent genital herpes. Genitourin Med 1993;69: 457-9.