Establishment of an animal model for myoglobinuria by use of a myotoxin from Pseudechis australis (King Brown Snake) venom in mice

Laboratory Animal Science

Volumn 46, Issue 4, 1996, Pages 393-398

  Ponraj, Durairaj ^a   Gopalakrishnakone, Ponnambalam ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

MYOGLOBIN; SNAKE VENOM;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; MOUSE; MUSCLE NECROSIS; MYOGLOBINURIA; NEPHROTOXICITY; NONHUMAN; PROTEIN LOCALIZATION; RHABDOMYOLYSIS; SOLEUS MUSCLE;

ANIMALS; CELL MEMBRANE; DISEASE MODELS, ANIMAL; IMMUNOENZYME TECHNIQUES; KIDNEY; KIDNEY DISEASES; KIDNEY TUBULES; MALE; MICE; MICROSCOPY, ELECTRON; MUSCLE, SKELETAL; MUSCULAR DISEASES; MYOGLOBIN; MYOGLOBINURIA; NECROSIS; RHABDOMYOLYSIS; SARCOPLASMIC RETICULUM; SNAKE VENOMS;

EID: 0029792786     PISSN: 00236764     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Kawai, H., Y. Nishida, K. Masuda, et al. 1987. Localization of myoglobin in human muscle cells by immunoelectron microscopy. Muscle Nerve 10:144-149.
2. Rowland, L. P. 1984. Myoglobinuria. Can. J. Neurol. Sci. 11:1-13.
3. Gopalakrishnakone, P., M. C. E. Gwee, and S. Z. J. Chen. 1994. Myoglobinuria caused by venoms and toxins, p. 53. Abstr. 11th World Congress on Animal, Plant and Microbial Toxins, Tel Aviv, Israel.
4. Mebs, D., and Y. Samejima. 1980. Purification, from Australian elapids venoms, and properties of phospholipase A which cause myoglobinuria in mice. Toxicon 18:161-168.
5. Chen, S. Z. J., P. Gopalakrishnakone, and M. C. E. Gwee. 1994. Pharmacological effects and pathological changes induced by the venom of Pseudechis australis in isolated skeletal muscle preparation. Toxicon 32:303-315.
6. Leonarde, T. M., E. H. Howsen, and I. Spence. 1979. A lethal myotoxin isolated from the venom of the Australian king brown snake. Toxicon 17:544-555.
7. Rowlands, J. B., F. L. Mastaglia, B. A. Kakulas, et al. 1969. Clinical and pathological aspects of a fatal case of mulga (Pseudechis australis) snake bite. Med. J. Aus. 1:226-230.
8. Herrera, G. A. 1994. Myoglobin and the kidney: an overview. Ultrastruct. Pathol. 18:113-117.
9. Herrera, E. A. T. 1994. Myoglobinuric acute renal failure associated with cocaine use. Ultrastruct. Pathol. 18:127-131.
10. Gabow, P. A., W. D. Kaehny, and S. P. Kelleher. 1982. The spectrum of rhabdomyolysis. Medicine 61:141-152.
11. Honda, N. 1983. Acute renal failure and rhabdomyolysis. Kidney Int. 23:888-898.
12. Ownby, C. L. 1990. Locally acting agents myotoxins, hemorrhagic toxins and dermonecrotic factors, p. 601-654. In W. T. Shier and D. Mebs (ed.), Handbook of toxinology. Marcel Dekker, Inc., New York.
13. Harris, J. B., and M. J. Cullen. 1990. Muscle necrosis caused by snake venoms and toxins. Electron Microscopy Rev. 3:183-211.
14. Korenyi-Both, A. 1983. Pattern of necrosis and autoimmune disease of skeletal muscle, p. 45-56, 397. In A. Korenyi-Both (ed.), Muscle pathology in neuromuscular disease. Charles C Thomas, Publisher, Springfield, Ill.
15. Herrera, G. A. 1994. Low molecular weight proteins and the kidney: physiologic and pathologic considerations. Ultrastruct. Pathol. 18:89-98.
16. Ponraj, D., and P. Gopalakrishnakone. 1995. Morphological changes induced by a generalized myotoxin (myoglobinuria-inducing toxin) from the venom of Pseudechis australis (king brown snake) in skeletal muscle and kidney of mice. Toxicon 33:1453-1467.