Regional differences in nitric oxide-dependent vascular responses to somatostatin

Physiological Research

Volumn 45, Issue 4, 1996, Pages 291-296

  Dezsi L ^a,b   Szentivanyi Jr M ^a   Dornyei G ^a   Lowenstein L ^a   Farago M ^a   Tulassay, T ^b   Monos, E ^a  

^a Experimental Research Department   (Hungary)

^b SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

Author keywords

endothelium mediated vasodilatation; mesenteric vessels; peptide hormone; saphenous vessels

Indexed keywords

N(G) NITROARGININE; NITRIC OXIDE; SOMATOSTATIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DOSE RESPONSE; NONHUMAN; REGULATORY MECHANISM; SUPERIOR MESENTERIC ARTERY; VASODILATATION;

ACETYLCHOLINE; ANIMALS; CATS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; MESENTERIC ARTERIES; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NOREPINEPHRINE; RATS; SAPHENOUS VEIN; SOMATOSTATIN; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 0029792345     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. BOLTON T.B., CLAPP L.H.: Endothelial-dependent relaxant actions of carbachol and substance P in arterial smooth muscle. Br. J. Pharmacol. 87: 713-723, 1986.
2. CHERRY P.D., FURCHGOTT R.F., ZAWADZKI J.V., JOTHIANANDAN D.: Role of endothelial cells in relaxation of isolated arteries by bradykinin. Proc. Natl. Acad. Sci. U.S.A 79: 2106-2110, 1982.
3. DAVIES J.M., WILLAMS K.I.: Endothelial-dependent relaxant effect of vasoactive intestinal polypeptide and arachidonic acid in rat aortic strips. Prostaglandins 27: 195-202, 1984.
4. DÉZSI L., HAMAR J.: Effect of intraarterial somatostatin infusion on SMA blood flow. Acta Physiol. Hung. 71: 91-97, 1988.
5. FRANCO-CERECEDA A., RUDEHILL A.: Capsaicin-induced vasodilatation of human coronary arteries in vitro is mediated by calcitonin gene-related peptide rather than substance P or neurokinin A. Acta Physiol. Scand. 136: 575-580, 1989.
6. KONTUREK S.J., TASLER J., JAWOREK J., PAWLIK W., WALUS K.N., SCHUSDZIARRA A.V., MEYERS C.A., COY D.H., SCHALLY A.V.: Gastrointestinal secretory, motor, circulatory, and metabolic effects of prosomatostatin. Proc. Natl. Acad. Sci. U.S.A. 78: 1967-1971, 1981.
7. KRAVETZ D., BOSCH J., ARDERIU M.T., PIZCUETA M.P., CASAMITJANA R., RIVERA F., RODES J.: Effects of somatostatin on splanchnic hemodynamics and plasma glucagon in portal hypertensive rats. Am. J. Physiol. 254: G322-G328, 1988.
8. KRULICH I, DHARIWAL A.P. S., McCANN S.M.: Stimulatory and inhibitory effect of purified hypothalamic extracts on growth hormone release from rat pituitary in vivo. Endocrinology 83: 783-790, 1968.
9. LONG J.B., RIGAMONTI D.D., DOSAKA K., KRAIMER J.M., MARTINEZ-ARIZALA A: Somatostatin causes vasoconstriction, reduces blood flow and increases vascular permeability in the rat central nervous system. J. Pharmacol. Exp. Ther. 260: 1425-1432, 1992.
10. LUU T.N., CHESTER A.H., O'NEIL G.S., TADJKARIMI S., YACOUB M.H.: Effects of vasoactive neuropeptides on human saphenous vein. Br. Heart J. 67: 474-477, 1992.
11. MÄNNL H.F.K., FARTHMANN E.H.: Verminderung der Magendurchblutung durch Somatostatin. In: Somatostatin. Klinische und Experimentelle Ergebnisse. H. BÜNTE (ed). Falk Foundation, Freiburg, 1982, pp. 25-34.
12. MONOS E., CONTNEY S.J., COWLEY A.W. Jr., STEKIEL WJ.: Electrical and mechanical responses of rat saphenous vein to short-term pressure load. Am. J. Physiol. 256: H47-H55, 1989.
13. MONOS E., CONTNEY S.J., DORNYEI G., COWLEY A.W. Jr., BOSNJAK Z., STEKIEL W.J.: Hyperpolarisation of in situ rat saphenous vein in response to axial stretch. Am. J. Physiol. 265: H857-H861, 1993.
14. SAMUELSON U.E., JERNBECK J.: Calcitonin gene-related peptide relaxes porcine arteries via one endothelium-dependent and one endothelium-independent mechanism. Acta Physiol. Scand. 141: 281-282, 1991.
15. SCHALLY A.V., COY B.H., MEYERS CA.: Hypothalamic regulatory hormones. Annu. Rev. Biochem. 47: 89-128, 1978.
16. SZABÓ C., BÉRCZI V., SCHNEIDER F., KOVÁCH A.G.B., MONOS E.: Role of endothelium in the response of the vein wall to magnesium withdrawal. Pflügers Arch. 420: 140-145, 1992.
17. TJEN A LOOI S., EKMAN R., LIPPTON H., CARY J., KEITH I.: CGRP and somatostatin modulate chronic pulmonary hypertension. Am. J. Physiol. 263: H681-H690, 1992.
18. TÖRNEBRANDT K., NOBIN A., OWMAN C.H.: Contractile and dilatory action of neuropeptides on isolated human mesenteric blood vessels. Peptides 8: 251-256, 1987.