Differential activity and lack of synergy of lung surfactant proteins SP-B and SP-C in interactions with phospholipids

Journal of Lipid Research

Volumn 37, Issue 8, 1996, Pages 1749-1760

  Wang, Zhengdong ^a   Gurel, Okyanus ^a   Baatz, John E ^d   Notter, Robert H ^a,b,c  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

^c University of Rochester   (United States)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

apoproteins; DPPC; lung surfactant; phospholipids; PPL; SP B; SP C; synergy

Indexed keywords

APOPROTEIN; DIPALMITOYLPHOSPHATIDYLCHOLINE; LUNG SURFACTANT; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLGLYCEROL; PHOSPHOLIPID; SERUM ALBUMIN;

ADSORPTION; ANIMAL TISSUE; ARTICLE; CATTLE; CONTROLLED STUDY; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; SURFACE PROPERTY; SURFACE TENSION;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; ADSORPTION; ANIMALS; CATTLE; OSCILLOMETRY; PHOSPHOLIPIDS; PRESSURE; PROTEOLIPIDS; PULMONARY SURFACTANTS; SERUM ALBUMIN, BOVINE; SURFACE PROPERTIES; TIME FACTORS;

EID: 0029792174     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Goerke, J., and J. A. Clements. 1986. Alveolar surface tension and lung surfactant. In Handbook of Physiology. Section 3. The Respiratory System. American Physiological Society, Bethesda, MD. 247-261.
2. Notter, R. H. 1989. Physical chemistry and physiological activity of pulmonary surfactant. In Surfactant Replacement Therapy. D. L. Shapiro and R. H. Notter, editors. A. R. Liss, Inc., New York. 19-70.
3. Weaver, T. E., and J. A. Whitsett. 1991. Function and regulation of expression of pulmonary surfactant-associated proteins. Biochem. J. 273: 249-264.
4. Keough, K. M. W. 1992. Physical chemistry of pulmonary surfactant in the terminal air spaces. In Pulmonary Surfactant: From Molecular Biology to Clinical Practice. B. Robertson, L. M. G. van Golde, and J. J. Batenburg, editors. Elsevier, Amsterdam. 109-164.
5. Johansson, J., T. Curstedt, and B. Robertson. 1994. Proteins of the surfactant system. Eur. Respir. J. 7: 372-391.
6. Yu, S-H., and F. Possmayer. 1988. Comparative studies on the biophysical activities of the low-molecular-weight hydrophobic proteins purified from bovine pulmonary surfactant. Biochim. Biophys. Acta. 961: 337-350.
7. Takahashi, A., A. J. Waring, J. Amirkhanian, B. Fan, and H. W. Taeusch. 1990. Structure-function relationships of bovine pulmonary surfactant proteins: SP-B and SP-C. Biochim. Biophys. Acta. 1044: 43-49.
8. Yu, S-H., and F. Possmayer. 1990. Role of bovine pulmonary surfactant-associated proteins in the surface-active property of phospholipid mixtures. Biochim. Biophys. Acta. 1046: 233-241.
9. Oosterlaken-Dijksterhis, M. A., H. P. Haagsman, L. M. G. van Golde, and R. A. Demel. 1991. Interaction of lipid vesicles with monomolecular layers containing lung surfactant proteins SP-B and SP-C. Biochemistry. 30: 8276-8281.
10. Venkitaraman, A. R., J. E. Baatz, J. A. Whitsett, S. B. Hall, and R. H. Notter. 1991. Biophysical inhibition of synthetic phospholipid-lung surfactant apoprotein admixtures by plasma proteins. Chem. Phys. Lipids. 57: 49-57.
11. Taneva, S., and K. M. W. Keough. 1994. Pulmonary surfactant proteins SP-B and SP-C in spread monolayers at the air-water interface. III. proteins SP-B plus SP-C with phospholipids in spread monolayers. Biophys. J. 66: 1158-1166.
12. American Heritage Dictionary, 2nd College Edition. 1985. Houghton Mifflin Co., Boston, MA.
13. Venkitaraman, A. R., S. B. Hall, J. A. Whitsett, and R. H. Notter. 1990. Enhancement of biophysical activity of lung surfactant extracts and phospholipid-apoprotein mixtures by surfactant protein A. Chem. Phys. Lipids. 56: 185-194.
14. Hall, S. B., Z. Wang, and R. H. Notter. 1994. Separation of subfractions of the hydrophobic components of calf lung surfactant. J. Lipid Res. 55: 1386-1394.
15. Wang, Z., S. B. Hall, and R. H. Notter. 1995. Dynamic surface activity of films of lung surfactant phospholipids, hydrophobic proteins, and neutral lipids. J. Lipid Res. 36: 1283-1293.
16. Touchstone, J., J. Chen, and K. Beaver. 1980. Improved separation of phospholipids by thin-layer chromatography. Lipids. 15: 61-62.
17. Bligh, E. G., and W. J. Dyer. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37: 911-917.
18. Notter, R. H., R. D. Taubold, and J. N. Finkelstein. 1983. Comparative adsorption of natural lung surfactant, extracted phospholipids and artificial phospholipid mixtures to the air-liquid interface. Chem. Phys. Lipids. 33: 67-80.
19. Whitsett, J. A., B. L. Ohning, G. Ross, J. Meuth, T. Weaver, B. A. Holm, D. L. Shapiro, and R. H. Notter. 1986. Hydrophobic surfactant-associated protein in whole lung surfactant and its importance for biophysical activity in lung surfactant extracts used for replacement therapy. Pediatr. Res. 20: 460-467.
20. Wang, Z., S. B. Hall, and R. H. Notter. 1996. Roles of different hydrophobic constituents in the adsorption of pulmonary surfactant. J. Lipid Res. 37: 790-798.
21. Kaplan, R. S., and P. L. Pedersen. 1985. Sensitive protein assay in the presence of high levels of lipids. Anal. Biochem. 150: 97-104.
22. Schägger, H., and G. von Jagow. 1987. Tricine-sodium dodecyl sulfate gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166: 368-379.
23. Bartlett, G. R. 1959. Phosphorous assay in column chromatography. J. Biol. Chem. 234: 466-468.
24. Tabak, S. A., and R. H. Notter. 1977. A modified technique for dynamic surface pressure and relaxation measurements at the air-water interface. Rev. Sci. Instrum. 48: 1196-1201.
25. Turcotte, J. G., A. M. Sacco, J. M. Steim, S. A. Tabak, and R. H. Notter. 1977. Chemical synthesis and surface properties of an analog of the pulmonary surfactant dipalmitoyl phosphatidylcholine. Biochim. Biophys. Acta. 488: 235-248.
26. Notter, R. H., S. Holcomb, and R. D. Mavis. 1980. Dynamic surface properties of phosphatidylglycerol-dipalmitoyl phosphatidylcholine mixed films. Chem. Phys. Lipids. 27: 305-319.
27. Notter, R. H., S. A. Tabak, and R. D. Mavis. 1980. Surface properties of phosphatidylglycerol-dipalmitoyl phosphatidylcholine mixed films. J. Lipid Res. 21: 10-22.
28. Enhorning, G. 1977. Pulsating bubble technique for evaluation of pulmonary surfactant. J. Appl. Physiol. 43: 198-203.
29. Ames, B. N. 1966. Assay of inorganic phosphate, total phosphate, and phosphatases. Methods Enzymol. 8: 115-118.
30. Hall, S. B., M. S. Bermel, Y-T. Ko, H. J. Palmer, G. A. Enhorning, and R. H. Notter. 1993. Approximations in the measurement of surface tension on the oscillating bubble surfactometer. J. Appl. Physiol. 75: 468-477.
31. Notter, R. H., D. P. Penney, J. N. Finkelstein, and D. L. Shapiro. 1986. Adsorption of natural lung surfactant and phospholipid extracts related to tubular myelin formation. Pediatr. Res. 20: 97-101.
32. Curstedt, T., J. Johansson, P. Persson, A. Eklund, B. Robertson, B. Löwenadler, and H. Jörnvall. 1990. Hydrophobic surfactant-associated polypeptides: SP-C is a lipopeptide with two palmitoylated cysteine residues, whereas SP-B lacks covalently linked fatty acyl groups. Proc. Natl. Acad. Sci. USA. 87: 2985-2989.
33. deMello, D. E., L. M. Nogee, S. Heyman, H. F. Krous, M. Hussain, T. A. Merritt, W. Hsueh, J. E. Haas, K. Heidelberger, R. Schumacher, and H. R. Colten. 1994. Molecular and phenotypic variability in the congenital alveolar proteinosis syndrome associated with inherited surfactant protein B deficiency. J. Pediatr. 125: 43-50.
34. Williams, M. C., S. Hawgood, and R. L. Hamilton. 1991. Changes in lipid structure produced by surfactant proteins SP-A, SP-B, and SP-C. Am. J. Respir. Cell Mol. Biol. 5: 41-50.
35. Mizuno, K., M. Ikegami, C-M. Chen, T. Ueda, and A. H. Jobe. 1995. Surfactant protein-B supplementation improves in vivo function of a modified natural surfactant. Pediatr. Res. 37: 271-276.
36. Horowitz, A. D. 1995. Exclusion of SP-C, but not SP-B, by gel phase palmitoyl lipids. Chem. Phys. Lipids. 76: 27-39.
37. Curstedt, T., H. Jörnvall, B. Robertson, T. Bergman, and P. Berggren. 1987. Two hydrophobic low-molecular-mass protein fractions of pulmonary surfactant: Characterization and biophysical activity. Eur. J. Biochem. 168: 255-262.
38. Oosterlaken-Dijksterhuis, M. A., H. P. Haagsman, L. M. G. van Golde, and R. A. Demel. 1991. Characterization of lipid insertion into monomolecular layers mediated by lung surfactant proteins SP-B and SP-C. Biochemistry. 30: 10965-10971.
39. Seeger, W., A. Günther, and C. Thede. 1992. Differential sensitivity to fibrinogen inhibition of SP-C- vs. SP-B-based surfactants. Am. J. Physiol. 261: L286-L291.
40. Johansson, J., H. Jörnvall, A. Eklund, N. Christensen, B. Robertson, and T. Curstedt. 1988. Hydrophobic 3.7 kDa surfactant polypeptide: structural characterization of the human and bovine forms. FEBS Lett. 232: 61-64.
41. Glasser, S. W., T. R. Korfhagen, T. E. Weaver, T. Pilot-Matias, J. L. Fox, and J. A. Whitsett. 1987. cDNA and deduces amino acid sequence of human pulmonary surfactant-associated proteolipid SPL (Phe). Proc. Natl. Acad. Sci. USA. 84: 4007-4011.
42. Baatz, J. E., K. L. Smyth, J. A. Whitsett, C. Baxter, and D. R. Absolom. 1992. Structure and functions of a dimeric form of surfactant protein SP-C: a Fourier transform infra-red and surfactometry study. Chem. Phys. Lipids. 63: 91-104.
43. Vandenbussche, G., A. Clercx, T. Curstedt, J. Johansson, H. Jörnvall, and J. M. Ruysschaert. 1992. Structure and orientation of the surfactant-associated protein SP-C in a lipid bilayer. Eur. J. Biochem. 203: 201-209.
44. Morrow, M. R., J. Pérez-Gil, G. A. Simatos, C. Boland, J. Stewart, D. Absolom, V. Sarin, and K. M. W. Keough. 1993. Pulmonary surfactant-associated protein SP-B has little effect on acyl chains in dipalmitoylphosphatidylcholine dispersions. Biochemistry. 32: 4397-4402.
45. Vandenbussche, G., A. Clercx, M. Clercx, T. Curstedt, J. Johansson, H. Jörnvall, and J. M. Ruysschaert. 1992. Secondary structure and orientation of the surfactant protein SP-B in a lipid environment. A Fourier transform infrared spectroscopy study. Biochemistry. 31: 9169-9176.
46. Baatz, J. E., B. Elledge, and J. A. Whitsett. 1990. Surfactant protein SP-B induces ordering at the surface of model membrane bilayers. Biochemistry. 29: 6714-6720.
47. Pérez-Gil, J., C. Casals, and D. Marsh. 1995. Interactions of hydrophobic lung surfactant proteins SP-B and SP-C with dipalmitoylphosphatidylcholine and dipalmitoyl phosphatidylglycerol bilayers studies by electron spin resonance spectroscopy. Biochemistry. 34: 3964-3791.
48. Cochran, C. G., and S. D. Revak. 1991. Pulmonary surfactant protein B (SP-B): structure-function relationships. Science. 254: 566-568.
49. Simatos, G. A., K. B. Forward, M. R. Morrow, and K. M. W. Keough. 1990. Interaction between perdeuterated dimyristoylphosphatidylcholine and low molecular weight pulmonary surfactant protein SP-C. Biochemistry. 29: 5807-5814.
50. Horowitz, A. D., B. Elledge, J. A. Whitsett, and J. E. Baatz. 1992. Effects of lung surfactant proteolipid SP-C on the organization of model membrane lipids: a fluorescence study. Biochim. Biophys. Acta. 1107: 44-54.
51. Baatz, J. E., V. Sarin, D. R. Absolom, C. Baxter, and J. A. Whitsett. 1991. Effects of surfactant-associated protein SP-B synthetic analogues on the structure and surface activity of model membrane bilayers. Chem. Phys. Lipids. 60: 163-178.
52. Hawco, M. W., P. J. Davis, and K. M. W. Keough. 1981. Lipid fluidity in lung surfactant: monolayers of saturated and unsaturated lecithins. J. Appl. Physiol. 51: 509-515.
53. Liu, H., R. Z. Lu, J. G. Turcotte, and R. H. Notter. 1994. Dynamic interfacial properties of surface-excess films of phospholipids and phosphonolipid analogs. I. Effect of pH. J. Colloid Interface. Sci. 167: 378-390.
54. Liu, H., J. G. Turcotte, and R. H. Notter. 1994. Dynamic interfacial properties of surface-excess films of phospholipids and phosphonolipid analogs. II. Effect of chain linkage and headgroup structure. J. Colloid Interface. Sci. 167: 391-400.