Distributional change of alpha-tocopherol in the rat lens with age

Ophthalmic Research

Volumn 28, Issue 2, 1997, Pages 136-140

  Nagata, M ^a,c   Kojima, M ^a   Murano, H ^a   Sasaki, K ^a   Obara, Y ^b   Matsuura, K ^c   Takashina, H ^c  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

^b DOKKYO MEDICAL UNIVERSITY   (Japan)

^c SANTEN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Brown Norway rat; d Tocopherol; Gas chromatography mass spectrometry (GC MS); Lens; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL;

AGE; ANIMAL TISSUE; CONFERENCE PAPER; GAS CHROMATOGRAPHY; LENS; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION;

EID: 0029791996     PISSN: 00303747     EISSN: 14230259     Source Type: Journal    
DOI: 10.1159/000267969     Document Type: Article

References (25)

1. Vision Research, a National Plan: The Report of the Cataract Panel (NIH publication 83-2473). Washington. US Department Health Human Services. 1983. vol 2, part 3.
2. Ogino S, Yasukura K: Biochemical studies on cataract. VI. Production of cataratcs in guinea pigs with dini-trophenol. Am J Ophthalmol. 1957; 43:936-946.
3. Kosegarten DC, Maher TJ: Use of guinea pig as model to study galac-tosc-induced cataract formation. J PharmSci 1987;67:1478-1479.
4. Varma SD, Srivastava VK, Richards RD: Photooxidation in lens and cataract formation -Preventive role of Superoxide dismutase, cata-lase and vitamin C. Ophthalmic Res 1982;14:167-175.
5. Nishigori H, Hayashi R, Lee JW, Murayama K, Iwatsuru M: Preventive effect of ascorbic acid against glucocorticoid-induced cataract formation of developing chick embryos. Bxp Eye Res 1985:40: 445-451.
6. Vinson JA, Possanza CJ, Drack AV: The effect of ascorbic acid on galactose-induced cataracts. Nutr Rep Int 1986:33:665-668.
7. Blondin J, Baragi V, Schwartz E. Sadowski J, Taylor A: Delay of UV-induccd eye lens protein damage in guinea pig by dietary ascorbate. J Free Radic Biol Med 1986;2:27S-281.
8. Jacques PF, Hartz SC. Chylack LT, McGandy RB, Sadwski JA: Nutritional status in persons with and without senile cataract -Blood vitamin and mineral levels. Am J Clin Nutr 1988;48:152-158.
9. Nagata M, Tanioka H, Mibu H, Hi-kida M, Akiba M, Yamamoto I: Effect of ascorbic acid 2-O-a-glucoside on hydrocortisone-induccd cataract formation in developing chick embryos. I. Comparison of the preventive effect of ascorbic acid deri-vatcs. J Ocul Pharmacol 1993:9:59-68.
10. Nagata M, Hikida M, Mibu H, Muto N, Yamamoto I: Effect of ascorbic acid 2-O-a-glucoside on hydrocortisone-induced cataract formation in developing chick embryos. II. Influence on glutathione and lipid peroxide contents in the lens. J Ocul Pharmacol 1994; 10: 537-542.
11. Robertson JM, Donncr AP, Trevithick JR: Vitamin E intake and risk of cataracts in humans. Ann NY Acad Sci 1989;570:372-382.
12. Creighton MO, Trevithick JR: Cortical cataract formation prevented by vitamin E and glutathione. Exp Eye Res 1979;29:689-693.
13. Varma SD, Beachy NA, Richards RD: Photoperoxidation of lens lipids -Prevention by vitamin E. Pho-tochem Photobiol 1982:36:623-636.
14. Creighton MO, Ross WM, Stewart-DcHaan PJ, Sanwal M, Trevithick JR: Modeling conical cataractogen-esis. VII. Effects of vitamin E treatment on galactose-induced cataracts. Exp Eye Res 1985:40:213-222.
15. Tappel AL: Vitamin E and selenium protection from in vivo lipid peroxidation. Ann NY Acad Sci 1980: 3555:18-31.
16. Bessems GJH, Man BM, Hoenders HJ, Wollensak J: Alpha-tocophcrol in the normal and nuclear-catarac-tous human lens. Lens Res 1984-1985:2:233-242.
17. Hirai T, Majima Y, Ohta Y, Ishigu-ro I: Antioxidative role of vitamin E in rabbit lens. J Eye 1985;2:1174-1177.
18. Muller A, Moller B, Dragomirescu V, Hockwin O: Profiles of enzyme activities in bovine lenses; in Hockwin O (ed): Drug-Induced Ocular Side Effects and Ocular Toxicology. Concepts Toxicol. Basel. Karger 1987, vol 4, pp 343-349.
19. Kojima M: Enzymatic distribution patterns of rat lenses and the changes that occur during naphthalene caract development. Ophthalmic Res 1992;24:73-82.
20. Kneel P, Heliovaara M, Rissanen A, Aromaa A, Aaran RK: Scrum antioxidant vitamins and risk of cataract. BMJ 1992;305:1392-1394.
21. Costagliola C, Iuliano G, Menzione M, Nesti A, Simonelli F, Rinalidi E: Systemic human diseases as oxidative risk factors in cataractogcncsis. Ophthalmic Res 1988:20:308-316.
22. Vatassery GT, Johnson GJ, Kre-zowski AM: Changes in vitamin E concentrations in human plasma and platelets with age. J Am Coll Nutr 1983:4:369-375.
23. Dillon J, Mehlman B, Ponticorvo L. Spector A: The stage of neutral lipids in normal and cataractous human lenses. Exp Eye Res 1983;37: 91-98.
24. Von Heyningen R: Biochemistry of the lens: in Perkins ES. Hill DW (eds): Scientific Foundations of Ophthalmology. London, Heinc-mann. 1976.
25. Liebler DC, Kling DS, Reed DJ: Antioxidant protection of phospholipid bilaycr by a-tocopherol. J Biol Chcrn 1986;261:12114-12119.