메뉴 건너뛰기




Volumn 160-161, Issue , 1996, Pages 167-177

Uncoupling of mitochondrial oxidative phosphorylation alters lipid peroxidation-derived free radical production but not recovery of postischemic rat hearts and post-hypoxic endothelial cells

Author keywords

Endothelial cell reoxygenation; ESR spin trapping; Lipid radicals; Mitochondrial uncoupling; Myocardial reperfusion; Oxygen consumption

Indexed keywords

2,4 DINITROPHENOL; FREE RADICAL; N TERT BUTYL ALPHA PHENYLNITRONE;

EID: 0029791638     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00240047     Document Type: Article
Times cited : (18)

References (39)
  • 1
    • 0028089119 scopus 로고
    • Relative time-profiles for free radical trapping, coronary flow, enzyme leakage, arrhythmias and function during myocardial reperfusion
    • Blasig IE, Shuter S, Garlick P, Slater TF: Relative time-profiles for free radical trapping, coronary flow, enzyme leakage, arrhythmias and function during myocardial reperfusion. Free Rad Biol Med 16: 35-41, 1994
    • (1994) Free Rad Biol Med , vol.16 , pp. 35-41
    • Blasig, I.E.1    Shuter, S.2    Garlick, P.3    Slater, T.F.4
  • 2
    • 0027241908 scopus 로고
    • Generation of free radicals in Langendorff and working hearts during normoxia, hypoxia, and reoxygenation
    • Damerau W, Ibel J, Thürich T, Assadnazari A, Zimmer G: Generation of free radicals in Langendorff and working hearts during normoxia, hypoxia, and reoxygenation. Basic Res Cardiol 88: 141-119, 1993
    • (1993) Basic Res Cardiol , vol.88 , pp. 141-119
    • Damerau, W.1    Ibel, J.2    Thürich, T.3    Assadnazari, A.4    Zimmer, G.5
  • 3
    • 0025065449 scopus 로고
    • Luminol enhanced chemiluminescence of the perfused rat heart during ischemia and reperfusion
    • Kumar C, Okuda M, Ikai I, Chance B: Luminol enhanced chemiluminescence of the perfused rat heart during ischemia and reperfusion. FEBS Lett 272: 121-124, 1990
    • (1990) FEBS Lett , vol.272 , pp. 121-124
    • Kumar, C.1    Okuda, M.2    Ikai, I.3    Chance, B.4
  • 4
    • 0026475003 scopus 로고
    • Antioxidant properties of active and inactive isomers of nicardipin in cardiac membranes, endothelial cells, and perfused rat hearts
    • Mak IT, Kramer JH, Weglicki WB: Antioxidant properties of active and inactive isomers of nicardipin in cardiac membranes, endothelial cells, and perfused rat hearts. Coronary Artery Disease 3: 1095-1103, 1992
    • (1992) Coronary Artery Disease , vol.3 , pp. 1095-1103
    • Mak, I.T.1    Kramer, J.H.2    Weglicki, W.B.3
  • 5
    • 0026321147 scopus 로고
    • Is oxidative stress primarily involved in reperfusion injury of the ischemic heart?
    • Nohl H, Stolze K, Napetschnig S, Ishikawa T: Is oxidative stress primarily involved in reperfusion injury of the ischemic heart? Free Rad Biol Med 11: 581-588, 1991
    • (1991) Free Rad Biol Med , vol.11 , pp. 581-588
    • Nohl, H.1    Stolze, K.2    Napetschnig, S.3    Ishikawa, T.4
  • 6
    • 0025043862 scopus 로고
    • Ascorbyl free radical as a reliable indicator of free radical-mediated myocardial ischemic and postischemic injury. A real-time continuous flow ESR study
    • Pietri S, Culcasi M, Stella L, Cozzone PJ: Ascorbyl free radical as a reliable indicator of free radical-mediated myocardial ischemic and postischemic injury. A real-time continuous flow ESR study. Eur J Biochem 193: 845-854, 1990
    • (1990) Eur J Biochem , vol.193 , pp. 845-854
    • Pietri, S.1    Culcasi, M.2    Stella, L.3    Cozzone, P.J.4
  • 7
    • 0025195491 scopus 로고
    • Use of salicylate as a probe for ·OH formation in isolated ischemic rat hearts
    • Powell RS, Hall D: Use of salicylate as a probe for ·OH formation in isolated ischemic rat hearts. Free Rad Biol Med 9: 133-141, 1990
    • (1990) Free Rad Biol Med , vol.9 , pp. 133-141
    • Powell, R.S.1    Hall, D.2
  • 8
    • 0024455053 scopus 로고
    • Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion: Evidence that myocardial 'stunning' is manifestation of reperfusion injury
    • Bolli R, Jeroudi MO, Patel BS, Aruoma Oi, Halliwell B, Lai EK, McCay PB: Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion: Evidence that myocardial 'stunning' is manifestation of reperfusion injury. Circ Res 65: 607-622, 1989
    • (1989) Circ Res , vol.65 , pp. 607-622
    • Bolli, R.1    Jeroudi, M.O.2    Patel, B.S.3    Aruoma, Oi.4    Halliwell, B.5    Lai, E.K.6    McCay, P.B.7
  • 9
    • 0026644609 scopus 로고
    • Production of reactive oxygen by mitochondria from normoxic and hypoxic rat heart tissue
    • Paraidathanthiu T, DeGroot H, Kehrer JP: Production of reactive oxygen by mitochondria from normoxic and hypoxic rat heart tissue. Free Rad Biol Med 13: 289-297, 1992
    • (1992) Free Rad Biol Med , vol.13 , pp. 289-297
    • Paraidathanthiu, T.1    DeGroot, H.2    Kehrer, J.P.3
  • 10
    • 0024489069 scopus 로고
    • Quantitative estimation of the rate of superoxide radical generation in mitochondrial membranes by ESR-technique
    • Rashba YE, Vartanyan LS, Bayder LM, Krinitskaya LA: Quantitative estimation of the rate of superoxide radical generation in mitochondrial membranes by ESR-technique. Biofizika USSR 34: 57-62, 1989
    • (1989) Biofizika USSR , vol.34 , pp. 57-62
    • Rashba, Y.E.1    Vartanyan, L.S.2    Bayder, L.M.3    Krinitskaya, L.A.4
  • 11
    • 0024561513 scopus 로고
    • Ischemia-induced changes in myocardial paramagnetic metabolites: Implications for intracellular oxy-radical generation
    • Baker JE, Kalyanaraman B: Ischemia-induced changes in myocardial paramagnetic metabolites: Implications for intracellular oxy-radical generation. FEBS Lett 244: 311-314, 1989
    • (1989) FEBS Lett , vol.244 , pp. 311-314
    • Baker, J.E.1    Kalyanaraman, B.2
  • 13
    • 0024461666 scopus 로고
    • Effects of oxyradicals on oxymyoglobin. Deoxygenation, haem removal and iron release
    • Prasad MR, Engelman RM, Jones RM, Das DK: Effects of oxyradicals on oxymyoglobin. Deoxygenation, haem removal and iron release. Biochem J 263: 731-736, 1989
    • (1989) Biochem J , vol.263 , pp. 731-736
    • Prasad, M.R.1    Engelman, R.M.2    Jones, R.M.3    Das, D.K.4
  • 15
    • 0025194447 scopus 로고
    • 2- spin trapping on cardiac submitochondrial particles isolated from ischemic and non-ischemic myocardium
    • 2- spin trapping on cardiac submitochondrial particles isolated from ischemic and non-ischemic myocardium. J Mol Cell Cardiol 22: 893-899, 1990
    • (1990) J Mol Cell Cardiol , vol.22 , pp. 893-899
    • Ueta, H.1    Ogura, R.2    Sugiyama, M.3    Kagiyama, A.4    Shin, G.5
  • 17
    • 27044438674 scopus 로고
    • Detection of free radical production during myocardial reperfusion injury using electron spin resonance spin trapping
    • C. Rice-Evans and T. Dormandy (eds). Richelieu Press, London
    • Davies MJ, Garlick PB, Slater TF, Hearse DJ: Detection of free radical production during myocardial reperfusion injury using electron spin resonance spin trapping. In: C. Rice-Evans and T. Dormandy (eds). Free radicals: Chemistry, pathology and medicine. Richelieu Press, London, 1988, pp 303-319
    • (1988) Free Radicals: Chemistry, Pathology and Medicine , pp. 303-319
    • Davies, M.J.1    Garlick, P.B.2    Slater, T.F.3    Hearse, D.J.4
  • 18
    • 27044444955 scopus 로고
    • Association of endogenously produced OH radicals with anoxia reoxygenation injury in isolated rat myocytes
    • Abstract
    • Atiq Khalid M, Samara ZO, Ashraf M: Association of endogenously produced OH radicals with anoxia reoxygenation injury in isolated rat myocytes. FASEB J 5(5): A1282 (Abstract), 1991
    • (1991) FASEB J , vol.5 , Issue.5
    • Atiq Khalid, M.1    Samara, Z.O.2    Ashraf, M.3
  • 20
    • 0028364561 scopus 로고
    • Lipid peroxidation-derived free radical production and postischemic myocardial reperfusion injury
    • Kramer JH, Misik V, Weglicki WB: Lipid peroxidation-derived free radical production and postischemic myocardial reperfusion injury. Ann N Y Acad Sci 723: 180-196, 1994
    • (1994) Ann N Y Acad Sci , vol.723 , pp. 180-196
    • Kramer, J.H.1    Misik, V.2    Weglicki, W.B.3
  • 21
    • 0025916541 scopus 로고
    • Propranolol preserves ultrastructure in adult cardiocytes exposed to anoxia/reoxygenation: A morphometric analysis
    • Freedman AM, Kramer JH, Mak IT, Cassidy MM, Weglicki WB: Propranolol preserves ultrastructure in adult cardiocytes exposed to anoxia/reoxygenation: A morphometric analysis. Free Rad Biol Med 11: 197-206, 1991
    • (1991) Free Rad Biol Med , vol.11 , pp. 197-206
    • Freedman, A.M.1    Kramer, J.H.2    Mak, I.T.3    Cassidy, M.M.4    Weglicki, W.B.5
  • 22
    • 0026343732 scopus 로고
    • Propranolol reduces anoxia/reoxygenation-mediated injury of adult myocytes through an anti-radical mechanism
    • Kramer JH, Mak IT, Freedman AM, Weglicki WB: Propranolol reduces anoxia/reoxygenation-mediated injury of adult myocytes through an anti-radical mechanism. J Mol Cell Cardiol 23: 1231-1244, 1991
    • (1991) J Mol Cell Cardiol , vol.23 , pp. 1231-1244
    • Kramer, J.H.1    Mak, I.T.2    Freedman, A.M.3    Weglicki, W.B.4
  • 23
    • 0026664867 scopus 로고
    • Magnesium deficiency in vitro enhances free radical-induced intracellular oxidation and cytotoxicity in endothelial cells
    • Dickens BF, Weglicki WB, Li Y-S, Mak IT: Magnesium deficiency in vitro enhances free radical-induced intracellular oxidation and cytotoxicity in endothelial cells. FEBS Lett 311: 187-191, 1992
    • (1992) FEBS Lett , vol.311 , pp. 187-191
    • Dickens, B.F.1    Weglicki, W.B.2    Li, Y.-S.3    Mak, I.T.4
  • 24
    • 0028942649 scopus 로고
    • Phospholipid hydroperoxides are precursors of lipid alkoxyl radicals produced from anoxia/reoxygenated endothelial cells
    • Kramer JH, Dickens BF, Misik V, Weglicki WB: Phospholipid hydroperoxides are precursors of lipid alkoxyl radicals produced from anoxia/reoxygenated endothelial cells. J Mol Cell Cardiol 27: 371-381, 1995
    • (1995) J Mol Cell Cardiol , vol.27 , pp. 371-381
    • Kramer, J.H.1    Dickens, B.F.2    Misik, V.3    Weglicki, W.B.4
  • 25
    • 27044443507 scopus 로고
    • Improvement of heart function by the spin trap alpha-phenyl-t-butyl nitrone possibly caused by its nitroxyl radical adduct
    • K.J.A. Davies (ed.) Pergamon Press, New York
    • Blasig IE, Schönheit K: Improvement of heart function by the spin trap alpha-phenyl-t-butyl nitrone possibly caused by its nitroxyl radical adduct. In. K.J.A. Davies (ed.) Oxidative damage and repair: Chemical, biological and medical aspects. Pergamon Press, New York, 1992, pp 421-425
    • (1992) Oxidative Damage and Repair: Chemical, Biological and Medical Aspects , pp. 421-425
    • Blasig, I.E.1    Schönheit, K.2
  • 26
    • 0027459499 scopus 로고
    • Effects of the spin trap alpha-phenyl N-tert-butyl nitrone on myocardial function and flow: A dose-response study in the open chest dog and in the isolated rat heart
    • Li X-Y, Sun J-Z, Bradamante S, Piccinini F, Bolli R: Effects of the spin trap alpha-phenyl N-tert-butyl nitrone on myocardial function and flow: a dose-response study in the open chest dog and in the isolated rat heart. Free Rad Biol Med 14: 277-285, 1993
    • (1993) Free Rad Biol Med , vol.14 , pp. 277-285
    • Li, X.-Y.1    Sun, J.-Z.2    Bradamante, S.3    Piccinini, F.4    Bolli, R.5
  • 27
    • 0027473299 scopus 로고
    • Vasodilatory and toxic effects of spin traps on aerobic cardiac function
    • Konorev EA, Baker JE, Joseph J, Kalyanaraman B: Vasodilatory and toxic effects of spin traps on aerobic cardiac function. Free Rad Biol Med 14: 127-137, 1993
    • (1993) Free Rad Biol Med , vol.14 , pp. 127-137
    • Konorev, E.A.1    Baker, J.E.2    Joseph, J.3    Kalyanaraman, B.4
  • 28
    • 0029019896 scopus 로고
    • Cardioprotective potency of the radical scavenger S-2-(3 aminopropionylamino) ethylphosphorothioic acid in the post-ischemic rat heart
    • Pissarek M, Jänichen F, Blasig IB, Haseloff RF, Keller T, Tapp E, Krause E-G: Cardioprotective potency of the radical scavenger S-2-(3 aminopropionylamino) ethylphosphorothioic acid in the post-ischemic rat heart. Mol Cell Biochem 145: 121-129, 1995
    • (1995) Mol Cell Biochem , vol.145 , pp. 121-129
    • Pissarek, M.1    Jänichen, F.2    Blasig, I.B.3    Haseloff, R.F.4    Keller, T.5    Tapp, E.6    Krause, E.-G.7
  • 29
    • 0023177080 scopus 로고
    • Free radicals and reperfusion-induced arrhythmias: Protection by spin trap agent PBN in the rat heart
    • Hearse DJ, Tosaki A: Free radicals and reperfusion-induced arrhythmias: protection by spin trap agent PBN in the rat heart. Circ Res 60: 375-383, 1987
    • (1987) Circ Res , vol.60 , pp. 375-383
    • Hearse, D.J.1    Tosaki, A.2
  • 30
    • 0027054967 scopus 로고
    • Does the antiarrhythmic effect of DMPO originate from its oxygen radical trapping property or the structure of the molecule itself?
    • Tosaki A, Haseloff RF, Hellegouarch A, Schonheit K, Martin VV, Das DK, Blasig IE: Does the antiarrhythmic effect of DMPO originate from its oxygen radical trapping property or the structure of the molecule itself? Basic Res Cardiol 87: 536-547, 1992
    • (1992) Basic Res Cardiol , vol.87 , pp. 536-547
    • Tosaki, A.1    Haseloff, R.F.2    Hellegouarch, A.3    Schonheit, K.4    Martin, V.V.5    Das, D.K.6    Blasig, I.E.7
  • 31
    • 0011394401 scopus 로고
    • Nitrone spin trap compounds. Mode of cardioprotective action
    • Biasig IE, Volodarski LB, Tosaki: A. Nitrone spin trap compounds. Mode of cardioprotective action. Pharm Pharmacol Lett 3: 135-138, 1993
    • (1993) Pharm Pharmacol Lett , vol.3 , pp. 135-138
    • Biasig, I.E.1    Volodarski, L.B.2    Tosaki, A.3
  • 32
    • 0026645589 scopus 로고
    • Protective activity of the spin trap tert-butyl-alpha-phenyl nitrone (PBN) in reperfused rat heart
    • Bradamante S, Monti E, Paracchini L, Lazzarini E, Piccini F: Protective activity of the spin trap tert-butyl-alpha-phenyl nitrone (PBN) in reperfused rat heart. J Mol Cell Cardiol 24: 375-386,1992
    • (1992) J Mol Cell Cardiol , vol.24 , pp. 375-386
    • Bradamante, S.1    Monti, E.2    Paracchini, L.3    Lazzarini, E.4    Piccini, F.5
  • 33
    • 0007439615 scopus 로고
    • Subcellular distribution of two spin trapping agents in rat heart: Possible explanation for their different protective effects against doxorubicin-induced cardiotoxicity
    • Cova D, De Angelis L, Monti E, Piccinini F: Subcellular distribution of two spin trapping agents in rat heart: Possible explanation for their different protective effects against doxorubicin-induced cardiotoxicity Free Rad Res Commun 15: 353-360, 1991
    • (1991) Free Rad Res Commun , vol.15 , pp. 353-360
    • Cova, D.1    De Angelis, L.2    Monti, E.3    Piccinini, F.4
  • 34
    • 84916650576 scopus 로고
    • 2 formation and energy conservation
    • L. Flohe (ed.) Thieme-Verlag, Stuttgart
    • 2 formation and energy conservation. In. L. Flohe (ed.) Glutathione. Thieme-Verlag, Stuttgart, 1974, pp 228-236
    • (1974) Glutathione , pp. 228-236
    • Loschen, G.1    Azzi, A.2    Flohe, L.3
  • 35
    • 0025268283 scopus 로고
    • Inverse relationship between ESR spin trapping of oxyradicals and degree of functional recovery during myocardial reperfusion in isolated working rat heart
    • Biasig IE, Ebert B, Hennig C, Pali T, Tosaki A: Inverse relationship between ESR spin trapping of oxyradicals and degree of functional recovery during myocardial reperfusion in isolated working rat heart. Cardiovasc Res 24: 263-270, 1990
    • (1990) Cardiovasc Res , vol.24 , pp. 263-270
    • Biasig, I.E.1    Ebert, B.2    Hennig, C.3    Pali, T.4    Tosaki, A.5
  • 36
    • 0024456309 scopus 로고
    • Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues
    • Kloner RA, Przyklenk K, Whittaker P: Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues. Circulation 80: 1115-1127, 1989
    • (1989) Circulation , vol.80 , pp. 1115-1127
    • Kloner, R.A.1    Przyklenk, K.2    Whittaker, P.3
  • 37
    • 0000104045 scopus 로고
    • Measurement of endothelial cell free radical generation: Evidence for a central mechanism of free radical injury in postischemic tissues
    • Zweier JL, Kuppusamy P Lutty GA: Measurement of endothelial cell free radical generation: Evidence for a central mechanism of free radical injury in postischemic tissues. Proc Natl Acad Sci USA 85: 4046-4050, 1988
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4046-4050
    • Zweier, J.L.1    Kuppusamy, P.2    Lutty, G.A.3
  • 38
    • 27044432797 scopus 로고
    • Rapid alkoxyl radical production during endothelial cell hypoxia/reoxygenation
    • Abstract
    • Dickens BF, Weglicki WB, Li Y-S, Kramer JH: Rapid alkoxyl radical production during endothelial cell hypoxia/reoxygenation. FASEB J 5(5): A1283 (Abstract), 1991
    • (1991) FASEB J , vol.5 , Issue.5
    • Dickens, B.F.1    Weglicki, W.B.2    Li, Y.-S.3    Kramer, J.H.4
  • 39
    • 0025331588 scopus 로고
    • ESR spin trapping and NMR spectroscopy of the same heart shows correlation between energy depression and radical formation during post-ischemic reperfusion
    • Blasig IE, Steinschneider AY, Lakomkin VL, Ledenev AN, Korchazkina OV, Ruuge EK: ESR spin trapping and NMR spectroscopy of the same heart shows correlation between energy depression and radical formation during post-ischemic reperfusion. FEBS Lett 267: 29-32, 1990
    • (1990) FEBS Lett , vol.267 , pp. 29-32
    • Blasig, I.E.1    Steinschneider, A.Y.2    Lakomkin, V.L.3    Ledenev, A.N.4    Korchazkina, O.V.5    Ruuge, E.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.